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    Prdx2 peroxiredoxin 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29338, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.

    Intracerebral Hemorrhage-Induced Brain Injury in Rats: the Role of Extracellular Peroxiredoxin 2.
    Bian L, Zhang J, Wang M, Keep RF, Xi G, Hua Y., Free PMC Article

    07/24/2021
    Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-kappaB) Signaling Pathway.

    Peroxiredoxin2 (Prdx2) Reduces Oxidative Stress and Apoptosis of Myocardial Cells Induced by Acute Myocardial Infarction by Inhibiting the TLR4/Nuclear Factor kappa B (NF-κB) Signaling Pathway.
    Li H, Yang H, Wang D, Zhang L, Ma T., Free PMC Article

    05/22/2021
    Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage.

    Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage.
    Tan X, Chen J, Keep RF, Xi G, Hua Y., Free PMC Article

    09/26/2020
    Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats.

    Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats.
    Mahal Z, Fujikawa K, Matsuo H, Zahid HM, Koike M, Misumi M, Kaneko T, Mashimo T, Ohara H, Nabika T.

    09/19/2020
    a critical role for Trx1 and Prdx2 in the cardiac hypertrophy of H9c2 cells and in the transition from compensated hypertrophy to de-compensated hypertrophy in H9c2 cells.

    Alterations in NO/ROS ratio and expression of Trx1 and Prdx2 in isoproterenol-induced cardiac hypertrophy.
    Su H, Pistolozzi M, Shi X, Sun X, Tan W.

    05/19/2018
    Prdx2 may prevent H2O2 accumulation in Leydig cells, and may be important in oxidative stressinduced apoptosis and decreased testosterone production.

    Role of peroxiredoxin 2 in H2O2‑induced oxidative stress of primary Leydig cells.
    Duan T, Fan K, Chen S, Yao Q, Zeng R, Hong Z, Peng L, Shao Y, Yao B.

    03/25/2017
    Prdx 2 expression in perinatal rat brain remained largely unchanged.

    Expression of peroxiredoxin 1, 2, and 6 in the rat brain during perinatal development and in response to dexamethasone.
    Shim SY, Kim HS, Kim EK, Choi JH.

    06/30/2012
    Peroxiredoxin 2 is an important modulator of angiotensin II-induced podocyte injury.

    Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis.
    Hsu HH, Hoffmann S, Di Marco GS, Endlich N, Peter-Katalinić J, Weide T, Pavenstädt H., Free PMC Article

    02/11/2012
    ATP and exogenous H2O2 stimulated Prx II shifting from oxidized form to reduced form. RBA-2 astrocytes expressed Prx II that might also serve as a protective mechanism to control the concentration of reactive oxygen species.

    Elucidation of ATP-stimulated stress protein expression of RBA-2 type-2 astrocytes: ATP potentiate HSP60 and Cu/Zn SOD expression and stimulates pI shift of peroxiredoxin II.
    Chen HB, Chan YT, Hung AC, Tsai YC, Sun SH.

    10/5/2011
    Prx2 is implied in the regulation of hydrogen peroxide production in the bone marrow during aging.

    Proteomic analysis of interstitial fluid in bone marrow identified that peroxiredoxin 2 regulates H(2)O(2) level of bone marrow during aging.
    Wang W, Gou L, Xie G, Tong A, He F, Lu Z, Yao Y, Liu K, Li J, Tang M, Chen L, Yang J, Hu H, Wei YQ.

    12/11/2010
    peroxiredoxin II may be a unique antioxidant in the cardiac system and may represent a potential target for cardiac protection from oxidative stress-induced injury.

    Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis.
    Zhao W, Fan GC, Zhang ZG, Bandyopadhyay A, Zhou X, Kranias EG., Free PMC Article

    01/21/2010
    Data indicate that peroxiredoxin 2 is probably involved in the neurotrophic effect of PACAP and suggest that this protein may have a therapeutic potential for the treatment of some neurodegenerative diseases.

    Peroxiredoxin 2 is involved in the neuroprotective effects of PACAP in cultured cerebellar granule neurons.
    Botia B, Seyer D, Ravni A, Bénard M, Falluel-Morel A, Cosette P, Jouenne T, Fournier A, Vaudry H, Gonzalez BJ, Vaudry D.

    01/21/2010
    This enzyme is expressed in islets and in insulinoma and may play a role in protecting pancreatic cells against reactive oxygen species.

    Expression of a thioredoxin peroxidase in insulin-producing cells.
    Boschero AC, Stoppiglia LF, Collares-Buzato CB, Bosqueiro JR, Delghingaro-Augusto V, Leite A, Carvalho CP, Netto LE, Carneiro EM.

    01/21/2010
    Exposure to diesel exhaust particles elevated transcription of thioredoxin peroxidase 2 gene in rat alveolar macrophages.

    cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles.
    Koike E, Hirano S, Shimojo N, Kobayashi T.

    01/21/2010
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