GATA6 promotes fibrotic repair of tracheal injury through NLRP3 inflammasome-mediated epithelial pyroptosis. | GATA6 promotes fibrotic repair of tracheal injury through NLRP3 inflammasome-mediated epithelial pyroptosis. Li A, Gu L, He C, Li Y, Peng M, Liao J, Xiao R, Xu L, Guo S. | 09/27/2023 |
GATA6 Inhibits Neuronal Autophagy and Ferroptosis in Cerebral ischemia-reperfusion Injury Through a miR-193b/ATG7 axis-dependent Mechanism. | GATA6 Inhibits Neuronal Autophagy and Ferroptosis in Cerebral ischemia-reperfusion Injury Through a miR-193b/ATG7 axis-dependent Mechanism. Fan W, Rong J, Shi W, Liu W, Wang J, Tan J, Yu B, Tong J. | 06/16/2023 |
GATA4/6 regulate DHH transcription in rat adrenocortical autografts. | GATA4/6 regulate DHH transcription in rat adrenocortical autografts. Yoshida T, Takizawa N, Matsuda T, Yamada H, Kitada M, Tanaka S., Free PMC Article | 11/21/2020 |
GATA6 and StAR steroidogeneic genes are hypomethylated at specific CpG sites in prenatally androgenized rats | Hypomethylation of specific CpG sites in the promoter region of steroidogeneic genes (GATA6 and StAR) in prenatally androgenized rats. Salehi Jahromi M, Hill JW, Ramezani Tehrani F, Zadeh-Vakili A. | 09/22/2018 |
Elevated expression of steroidogenesis pathway genes; CYP17, GATA6 and StAR in prenatally androgenized rats. | Elevated expression of steroidogenesis pathway genes; CYP17, GATA6 and StAR in prenatally androgenized rats. Jahromi MS, Tehrani FR, Noroozzadeh M, Zarkesh M, Ghasemi A, Zadeh-Vakili A. | 01/28/2017 |
Sulforaphane can inhibit transcription factors GATA4/6 as well as p-JNK1/2 and p-ERK1/2 MAPK signaling pathways in the cardiomyocytes. | Sulforaphane suppresses cardiac hypertrophy by inhibiting GATA4/GATA6 expression and MAPK signaling pathways. Kee HJ, Kim GR, Kim IK, Jeong MH. | 10/10/2015 |
These results establish SHP as a novel antihypertrophic regulator that acts by interfering with GATA6 signaling. | Small heterodimer partner blocks cardiac hypertrophy by interfering with GATA6 signaling. Nam YS, Kim Y, Joung H, Kwon DH, Choe N, Min HK, Kim YS, Kim HS, Kim DK, Cho YK, Kim YH, Nam KI, Choi HC, Park DH, Suk K, Lee IK, Ahn Y, Lee CH, Choi HS, Eom GH, Kook H. | 05/23/2015 |
In this study, they examined whether or not the JNK signaling pathway participates in the cAMP-dependent proteolysis of GATA-6 since a JNK inhibitor, SP600125, inhibited the proteolysis. | cAMP-dependent proteolysis of GATA-6 is linked to JNK-signaling pathway. Ushijima H, Maeda M. | 10/27/2012 |
Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats. | Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats. Liu B, Wang XQ, Yu L, Zhou TF, Wang XM, Liu HM., Free PMC Article | 01/21/2010 |
GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1. | GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1. Zhou B, Francis TA, Yang H, Tseng W, Zhong Q, Frenkel B, Morrisey EE, Ann DK, Minoo P, Crandall ED, Borok Z., Free PMC Article | 01/21/2010 |
GATA6 and Evi-1 are highly expressed early during cardiogenesis of ES cells, suggesting that they may regulate expression of the calreticulin gene during cardiac development. | Regulation of the calreticulin gene by GATA6 and Evi-1 transcription factors. Qiu Y, Lynch J, Guo L, Yatsula B, Perkins AS, Michalak M. | 01/21/2010 |