Kisspeptin and lactational anestrus: Current understanding and future prospects. | Kisspeptin and lactational anestrus: Current understanding and future prospects. Uenoyama Y, Inoue N, Tsukamura H. | 09/6/2023 |
Epigenetic modification of Kiss1 gene expression in the AVPV is essential for female reproductive aging. | Epigenetic modification of Kiss1 gene expression in the AVPV is essential for female reproductive aging. Dai R, Xu W, Chen W, Cui L, Li L, Zhou J, Jin X, Wang Y, Wang L, Sun Y. | 12/3/2022 |
Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity. | Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity. Olaniyi KS, Areloegbe SE, Oyeleke MB. | 11/12/2022 |
Intrauterine LPS inhibited arcuate Kiss1 expression, LH pulses, and ovarian function in rats. | Intrauterine LPS inhibited arcuate Kiss1 expression, LH pulses, and ovarian function in rats. Magata F, Toda L, Sato M, Sakono T, Chambers JK, Uchida K, Tsukamura H, Matsuda F. | 10/15/2022 |
Sex-specific hypothalamic expression of kisspeptin, gonadotropin releasing hormone, and kisspeptin receptor in progressive demyelination model. | Sex-specific hypothalamic expression of kisspeptin, gonadotropin releasing hormone, and kisspeptin receptor in progressive demyelination model. Muñoz de la Torre LP, Trujillo Hernández A, Eguibar JR, Cortés C, Morales-Ledesma L. | 07/16/2022 |
Hyperandrogenism induces proportional changes in the expression of Kiss-1, Tac2, and DynA in hypothalamic KNDy neurons. | Hyperandrogenism induces proportional changes in the expression of Kiss-1, Tac2, and DynA in hypothalamic KNDy neurons. Okada H, Kanasaki H, Tumurbaatar T, Tumurgan Z, Oride A, Kyo S., Free PMC Article | 07/2/2022 |
Maternal hypothyroidism reduces the expression of the kisspeptin/Kiss1r system in the maternal-fetal interface of rats. | Maternal hypothyroidism reduces the expression of the kisspeptin/Kiss1r system in the maternal-fetal interface of rats. Santos BR, Dos Anjos Cordeiro JM, Santos LC, de Oliveira LS, Mendonça LD, Santos EO, de Macedo IO, Szawka RE, Serakides R, Silva JF. | 06/18/2022 |
Gene expression pattern of Kisspeptin and RFamide-related peptide (Rfrp) in the male Damaraland mole-rat hypothalamus. | Gene expression pattern of Kisspeptin and RFamide-related peptide (Rfrp) in the male Damaraland mole-rat hypothalamus. Voigt C, Bennett NC. | 04/2/2022 |
Mutual Interactions Between GnRH and Kisspeptin in GnRH- and Kiss-1-Expressing Immortalized Hypothalamic Cell Models. | Mutual Interactions Between GnRH and Kisspeptin in GnRH- and Kiss-1-Expressing Immortalized Hypothalamic Cell Models. Kanasaki H, Tumurbaatar T, Tumurgan Z, Oride A, Okada H, Kyo S. | 03/12/2022 |
Involvement of kisspeptin in androgen-induced hypothalamic endoplasmic reticulum stress and its rescuing effect in PCOS rats. | Involvement of kisspeptin in androgen-induced hypothalamic endoplasmic reticulum stress and its rescuing effect in PCOS rats. Yuan C, Huang WQ, Guo JH, Liu XY, Yang JZ, Chen JJ, Wu Y, Ruan YC, Liu JY, Cui YG, Diao FY, Chan HC. | 01/1/2022 |
ERbeta regulated ovarian kisspeptin plays an important role in oocyte maturation. | ERβ regulated ovarian kisspeptin plays an important role in oocyte maturation. Chakravarthi VP, Ghosh S, Housami SM, Wang H, Roby KF, Wolfe MW, Kinsey WH, Rumi MAK., Free PMC Article | 11/27/2021 |
Effects of Ovarian Transplant on Anti-Mullerian Hormone, Kisspeptin-1, and Kisspeptin-1 Receptor Levels in Rats. | Effects of Ovarian Transplant on Anti-Müllerian Hormone, Kisspeptin-1, and Kisspeptin-1 Receptor Levels in Rats. Risvanli A, Ocal H, Timurkaan N, Ipek P, Cevik A, Seker I. | 11/6/2021 |
The abnormal expression of kisspeptin regulates pro-inflammatory cytokines, cell viability and apoptosis of macrophages in hyperandrogenism induced by testosterone. | The abnormal expression of kisspeptin regulates pro-inflammatory cytokines, cell viability and apoptosis of macrophages in hyperandrogenism induced by testosterone. Li X, Li L, Ouyang D, Zhu Y, Yuan T. | 10/23/2021 |
Polycomb represses a gene network controlling puberty via modulation of histone demethylase Kdm6b expression. | Polycomb represses a gene network controlling puberty via modulation of histone demethylase Kdm6b expression. Wright H, Aylwin CF, Toro CA, Ojeda SR, Lomniczi A., Free PMC Article | 10/2/2021 |
MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway. | MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway. Li X, Xiao J, Li K, Zhou Y. | 07/3/2021 |
Investigation of Kisspeptin Role in Experimental Kidney Ischemia/Reperfusion Injury. | Investigation of Kisspeptin Role in Experimental Kidney Ischemia/Reperfusion Injury. Kudaibergenova A, Aydogdu N, Kandemir N, Aydin MA. | 02/27/2021 |
MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons. | MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons. Abreu AP, Toro CA, Song YB, Navarro VM, Bosch MA, Eren A, Liang JN, Carroll RS, Latronico AC, Rønnekleiv OK, Aylwin CF, Lomniczi A, Ojeda S, Kaiser UB., Free PMC Article | 02/6/2021 |
food restriction-related negative energy balance causes pubertal failure with suppression of arcuate nucleus Kiss1 and Pdyn expression and then subsequent gonadotropin secretion and ovarian function, while the positive energetic cues trigger puberty onset via an increase in Kiss1 and Pdyn expression and thus gonadotropin secretion and follicular development in female rats | Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats. Majarune S, Nima P, Sugimoto A, Nagae M, Inoue N, Tsukamura H, Uenoyama Y., Free PMC Article | 05/2/2020 |
Central injection of orexin A reduced hypothalamic kisspeptin expression. | Central Orexin A Affects Reproductive Axis by Modulation of Hypothalamic Kisspeptin/Neurokinin B/Dynorphin Secreting Neurons in the Male Wistar Rats. Hosseini A, Khazali H. | 10/19/2019 |
Central administration of KP-10 activates nesfatin-1- and OXT neurons, and may play an important role in the suppression of feeding in male rats. | Centrally administered kisspeptin suppresses feeding via nesfatin-1 and oxytocin in male rats. Saito R, Tanaka K, Nishimura H, Nishimura K, Sonoda S, Ueno H, Motojima Y, Yoshimura M, Maruyama T, Yamamoto Y, Kusuhara K, Ueta Y. | 08/31/2019 |
At the onset of puberty, the densities of kisspeptin and neurokinin B IR cells were significantly higher in the high-fat diet group than in the control group | The effect of diet control on puberty onset and immunoreactivity of kisspeptin and neurokinin B in female rats. Kim E, Chung MJ, Chung Y, Jun Y. | 05/4/2019 |
Metabolic regulation of female puberty is accomplished via hypothalamic AMPK-Kiss1 signaling. | Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling. Roa J, Barroso A, Ruiz-Pino F, Vázquez MJ, Seoane-Collazo P, Martínez-Sanchez N, García-Galiano D, Ilhan T, Pineda R, León S, Manfredi-Lozano M, Heras V, Poutanen M, Castellano JM, Gaytan F, Diéguez C, Pinilla L, López M, Tena-Sempere M., Free PMC Article | 05/4/2019 |
The hypothalamic mRNA level of kisspeptin 1 (Kiss1), which is a positive regulator of gonadotropin-releasing hormone/gonadotropins, was reduced by fasting. | Prenatal undernutrition attenuates fasting-induced reproductive dysfunction in pre-pubertal male rats. Iwasa T, Matsuzaki T, Yano K, Mayila Y, Irahara M. | 03/16/2019 |
These results provide important mechanistic insights into the protective effects of Kisspeptin against heat-induced oxidative stress. | Metabonomics Approach to Assessing the Modulatory Effects of Kisspeptin-10 on Liver Injury Induced by Heat Stress in Rats. Hou Y, Wang X, Ping J, Lei Z, Gao Y, Ma Z, Jia C, Zhang Z, Li X, Jin M, Li X, Suo C, Zhang Y, Su J., Free PMC Article | 03/2/2019 |
These results identify SIRT1-mediated inhibition of Kiss1 as key epigenetic mechanism by which nutritional cues and obesity influence mammalian puberty. | SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression. Vazquez MJ, Toro CA, Castellano JM, Ruiz-Pino F, Roa J, Beiroa D, Heras V, Velasco I, Dieguez C, Pinilla L, Gaytan F, Nogueiras R, Bosch MA, Rønnekleiv OK, Lomniczi A, Ojeda SR, Tena-Sempere M., Free PMC Article | 01/12/2019 |