| GPR35 acts a dual role and therapeutic target in inflammation. | GPR35 acts a dual role and therapeutic target in inflammation.
Wu Y, Zhang P, Fan H, Zhang C, Yu P, Liang X, Chen Y., Free PMC Article | 12/5/2023 |
| Increased GPR35 expression in human colorectal and pancreatic cancer samples: A preliminary clinical validation of a new biomarker. | Increased GPR35 expression in human colorectal and pancreatic cancer samples: A preliminary clinical validation of a new biomarker.
Mackiewicz T, Włodarczyk J, Zielińska M, Włodarczyk M, Durczyński A, Hogendorf P, Dziki Ł, Fichna J. | 07/31/2023 |
| Recent advances in GPR35 pharmacology; 5-HIAA serotonin metabolite becomes a ligand. | Recent advances in GPR35 pharmacology; 5-HIAA serotonin metabolite becomes a ligand.
Im DS. | 07/13/2023 |
| Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression. | Involvement of CXCL17 and GPR35 in Gastric Cancer Initiation and Progression.
Li Y, Liu A, Liu S, Yan L, Yuan Y, Xu Q., Free PMC Article | 01/14/2023 |
| Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists. | Mitochondrial remodeling and ischemic protection by G protein-coupled receptor 35 agonists.
Wyant GA, Yu W, Doulamis IP, Nomoto RS, Saeed MY, Duignan T, McCully JD, Kaelin WG Jr., Free PMC Article | 08/27/2022 |
| The GPR35 expression pattern is associated with overall survival in male patients with colorectal cancer. | The GPR35 expression pattern is associated with overall survival in male patients with colorectal cancer.
Mackiewicz T, Jacenik D, Talar M, Fichna J. | 08/13/2022 |
| Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma. | Expression and clinical significance of CXCL17 and GPR35 in endometrial carcinoma.
Hao J, Gao X, Wang YP, Liu Q, Zhu H, Zhao SJ, Qin QH, Meng J, Li LL, Lin SC, Song Z, Li H. | 04/23/2022 |
| GPR35 in Intestinal Diseases: From Risk Gene to Function. | GPR35 in Intestinal Diseases: From Risk Gene to Function.
Kaya B, Melhem H, Niess JH., Free PMC Article | 12/25/2021 |
| GPR35 regulates osteogenesis via the Wnt/GSK3beta/beta-catenin signaling pathway. | GPR35 regulates osteogenesis via the Wnt/GSK3β/β-catenin signaling pathway.
Zhang Y, Shi T, He Y. | 07/24/2021 |
| Inflammatory bowel disease susceptible gene GPR35 promotes bowel inflammation in mice. | Inflammatory bowel disease susceptible gene GPR35 promotes bowel inflammation in mice.
Yansen Z, Lingang Z, Dali L, Mingyao L. | 03/27/2021 |
| Activation of the G-protein coupled receptor GPR35 by human milk oligosaccharides through different pathways. | Activation of the G-protein coupled receptor GPR35 by human milk oligosaccharides through different pathways.
Foata F, Sprenger N, Rochat F, Damak S., Free PMC Article | 01/9/2021 |
| high level expression of G protein-coupled receptor 35 V2/3 mRNA in regional lymph nodes of colon cancer patients is a sign of poor prognosis. | Utility of G protein-coupled receptor 35 expression for predicting outcome in colon cancer.
Ali H, AbdelMageed M, Olsson L, Israelsson A, Lindmark G, Hammarström ML, Hammarström S, Sitohy B. | 07/13/2019 |
| The histology of colon sections from GPR35(-/-) mice with dextran sulfate sodium-induced colitis showed extensive pathological changes including submucosal edema, diffuse ulcerations, and evidence of complete loss of crypts compared to wild-type mice with DSS-induced colitis. | Disruption of GPR35 Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice.
Farooq SM, Hou Y, Li H, O'Meara M, Wang Y, Li C, Wang JM., Free PMC Article | 04/20/2019 |
| Immunoreactivity for GPR35 was detected in normal corneas, keratoconus and Fuchs' dystrophy, mainly in the corneal epithelium and endothelium. In corneas with Fuchs' dystrophy, less intensive immunoreactivity for GPR35 in endothelium was revealed. | The presence and distribution of G protein-coupled receptor 35 (GPR35) in the human cornea - Evidences from in silico gene expression analysis and immunodetection.
Matysik-Woźniak A, Wnorowski A, Turski WA, Jóźwiak K, Jünemann A, Rejdak R. | 04/20/2019 |
| We performed a label-free kinome short hairpin RNA screen and identified a putative signaling network of GPR35 in HT-29 cells, some of which was validated using gene expression, biochemical and cellular assays. The results showed that GPR35 induced hypoxia-inducible factor 1alpha, and was involved in synaptic transmission, sensory perception, the immune system, and morphogenetic processes. | Chemical genomic analysis of GPR35 signaling.
Hu HH, Deng H, Ling S, Sun H, Kenakin T, Liang X, Fang Y. | 03/17/2018 |
| Using exome array data, we identified GPR35 as a novel susceptibility gene associated with chronic AIC in pediatric cancer patients | Exome array analysis identifies GPR35 as a novel susceptibility gene for anthracycline-induced cardiotoxicity in childhood cancer.
Ruiz-Pinto S, Pita G, Patiño-García A, Alonso J, Pérez-Martínez A, Cartón AJ, Gutiérrez-Larraya F, Alonso MR, Barnes DR, Dennis J, Michailidou K, Gómez-Santos C, Thompson DJ, Easton DF, Benítez J, González-Neira A. | 03/3/2018 |
| GPR35 interacts with CXCL17 in breast cancer cells. | The role and clinical significance of the CXCL17-CXCR8 (GPR35) axis in breast cancer.
Guo YJ, Zhou YJ, Yang XL, Shao ZM, Ou ZL. | 10/28/2017 |
| Small molecules that stimulate or block GPR35 activity can modulate vascular proliferation and migration. | G-Protein-Coupled Receptor 35 Mediates Human Saphenous Vein Vascular Smooth Muscle Cell Migration and Endothelial Cell Proliferation.
McCallum JE, Mackenzie AE, Divorty N, Clarke C, Delles C, Milligan G, Nicklin SA., Free PMC Article | 09/9/2017 |
| This article shows that GPR35 is the receptor of CXCL17. | Cutting edge: GPR35/CXCR8 is the receptor of the mucosal chemokine CXCL17.
Maravillas-Montero JL, Burkhardt AM, Hevezi PA, Carnevale CD, Smit MJ, Zlotnik A., Free PMC Article | 02/27/2016 |
| Single-nucleotide polymorphism in GPR35 gene is associated with Crohn's disease. | Immunochip analysis identification of 6 additional susceptibility loci for Crohn's disease in Koreans.
Yang SK, Hong M, Choi H, Zhao W, Jung Y, Haritunians T, Ye BD, Kim KJ, Park SH, Lee I, Kim WH, Cheon JH, Kim YH, Jang BI, Kim HS, Choi JH, Koo JS, Lee JH, Jung SA, Shin HD, Kang D, Youn HS, Taylor KD, Rotter JI, Liu J, McGovern DP, Song K., Free PMC Article | 09/26/2015 |
| results clearly show that R4.60, R(164), R(167), and R6.58 play crucial roles in the agonist initiated activation of GPR35. | Crucial positively charged residues for ligand activation of the GPR35 receptor.
Zhao P, Lane TR, Gao HG, Hurst DP, Kotsikorou E, Le L, Brailoiu E, Reggio PH, Abood ME., Free PMC Article | 04/12/2014 |
| GPR35 shows associations in both ulcerative colitis (UC) and primary sclerosing cholangitis (PSC), whereas TCF4 represents a PSC risk locus not associated with UC. Both loci may represent previously unexplored aspects of PSC pathogenesis. | Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4.
Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK, Wijmenga C, Ponsioen CY, Mathew CG, Rutgeerts P, Vermeire S, Schrumpf E, Hov JR, Manns MP, Boberg KM, Schreiber S, Franke A, Karlsen TH. | 02/15/2014 |
| This review presents a summary of what is known about the G-protein coupled receptors GPR35 and GPR55 and their potential characterization as lysophospholipid or cannabinoid receptors, respectively--{REVIEW} | GPR55 and GPR35 and their relationship to cannabinoid and lysophospholipid receptors.
Zhao P, Abood ME. | 04/20/2013 |
| screening assays used to identification of small MW agonists; some compounds are species-specific agonists; agonists/ligands include zaprinast, cromolyn & dicumarol | Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.
Jenkins L, Brea J, Smith NJ, Hudson BD, Reilly G, Bryant NJ, Castro M, Loza MI, Milligan G. | 01/8/2011 |
| human iNKT cells express GPR35 functionally active in reducing IL-4 release. | Expression of functional GPR35 in human iNKT cells.
Fallarini S, Magliulo L, Paoletti T, de Lalla C, Lombardi G. | 09/13/2010 |