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    Nrep neuronal regeneration related protein [ Mus musculus (house mouse) ]

    Gene ID: 27528, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    P311 regulates distal lung development via its interaction with several binding proteins.

    P311 regulates distal lung development via its interaction with several binding proteins.
    Liu Y, Zhou X, Hu N, Wang C, Zhao L.

    08/14/2021
    Butyrate alleviates diabetic kidney disease by mediating the miR-7a-5p/P311/TGF-beta1 pathway.

    Butyrate alleviates diabetic kidney disease by mediating the miR-7a-5p/P311/TGF-β1 pathway.
    Du Y, Yang YT, Tang G, Jia JS, Zhu N, Yuan WJ.

    03/6/2021
    Neuronal regeneration related protein (P311) overexpression enhanced adipogenic differentiation of 3T3-L1 cells.

    P311, a novel intrinsically disordered protein, regulates adipocyte development.
    Nunez S, Young C, Adebayo O, Muppuru KM, Badri KR., Free PMC Article

    07/4/2020
    The essential function of P311 in TGF-beta-mediated lung fibrosis.P311 regulates TGF-beta1, TGF-beta2 and TGF-beta3 translation in the lung fibrosis.

    P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-β1, -β2, and -β3 Translation.
    Duan FF, Barron G, Meliton A, Mutlu GM, Dulin NO, Schuger L., Free PMC Article

    12/28/2019
    P311 is a novel TGFbeta1/Smad signaling-mediated regulator of transdifferentiation in epidermal stem cells during cutaneous wound healing.

    P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression.
    Li H, Yao Z, He W, Gao H, Bai Y, Yang S, Zhang L, Zhan R, Tan J, Zhou J, Takata M, Wu J, Luo G., Free PMC Article

    11/11/2017
    P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation.

    P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation.
    Yao Z, Li H, He W, Yang S, Zhang X, Zhan R, Xu R, Tan J, Zhou J, Wu J, Luo G.

    09/23/2017
    These studies demonstrate that P311 is required for the production of normal cutaneous scars

    Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-β1 to -β3 Translation.
    Cheng T, Yue M, Aslam MN, Wang X, Shekhawat G, Varani J, Schuger L., Free PMC Article

    05/20/2017
    P311 plays a key role in renal fibrosis via TGFbeta1/Smad signaling, which could be a novel target for the management of renal fibrosis.

    P311 promotes renal fibrosis via TGFβ1/Smad signaling.
    Yao Z, Yang S, He W, Li L, Xu R, Zhang X, Li H, Zhan R, Sun W, Tan J, Zhou J, Luo G, Wu J., Free PMC Article

    10/22/2016
    P311 is central to reactive oxygen species-mediated hepatic stellate cell migration induced by different chemokines.

    P311 modulates hepatic stellate cells migration.
    Guimarães EL, Stradiot L, Mannaerts I, Schroyen B, van Grunsven LA.

    12/19/2015
    P311 is the first protein identified to modulate TGF-beta translation and the first pan-regulator of TGF-beta expression.

    Blood pressure homeostasis is maintained by a P311-TGF-β axis.
    Badri KR, Yue M, Carretero OA, Aramgam SL, Cao J, Sharkady S, Kim GH, Taylor GA, Byron KL, Schuger L., Free PMC Article

    11/30/2013
    P311 may promote the migration of ESCs both in micewith superficial partial-thickness burns and in an injured cell model in vitro, and it may play an important role in wound healing.

    [Effects of P 311 on the migration of epidermal stem cells in mice with superficial partial-thickness burn and injured cell model in vitro].
    Sun W, Yao ZH, Zhan RX, Zhang XR, Cui YY, Tan JL, Yang SS, Hu XH, Zhou JY, Wu J, Luo GX.

    06/22/2013
    these data establish P311 as playing an important role in learning and memory processes and emotional responses

    Behavioral characterization of P311 knockout mice.
    Taylor GA, Rodriguiz RM, Greene RI, Daniell X, Henry SC, Crooks KR, Kotloski R, Tessarollo L, Phillips LE, Wetsel WC., Free PMC Article

    01/21/2010
    A novel role for P311 in an alternative pathway of lipid-droplet accumulation that is induced by the regeneration-inducing molecule retinoic acid.

    P311 functions in an alternative pathway of lipid accumulation that is induced by retinoic acid.
    Leung JK, Cases S, Vu TH., Free PMC Article

    01/21/2010
    formalin-induced avoidance behavior, which reflects pain-related negative emotion, was significantly attenuated in P311-/- mice

    Involvement of P311 in the affective, but not in the sensory component of pain.
    Sun YG, Gao YJ, Zhao ZQ, Huang B, Yin J, Taylor GA, Chen ZF., Free PMC Article

    01/21/2010
    role for P311 in inducing TGF-beta1-independent myofibroblast transformation

    P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype.
    Pan D, Zhe X, Jakkaraju S, Taylor GA, Schuger L., Free PMC Article

    01/21/2010
    P311 expression is tightly regulated during the critical periods of alveolar formation, and that under pathologic conditions, its relative absence may contribute to failure of alveolar regeneration and lead to the development of human emphysema.

    Identification of P311 as a potential gene regulating alveolar generation.
    Zhao L, Leung JK, Yamamoto H, Goswami S, Kheradmand F, Vu TH., Free PMC Article

    01/21/2010
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