| Amphiphysin-IgG autoimmune sciatic neuropathy and facial neuropathy related to primary central nervous system lymphoma: A case report. | Amphiphysin-IgG autoimmune sciatic neuropathy and facial neuropathy related to primary central nervous system lymphoma: A case report.
Yao X, Zhang C, Zhang Y, Geng J, Bai S, Hao Y, Guan Y. | 10/4/2023 |
| Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction. | Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.
Zhang X, Zou L, Meng L, Xiong M, Pan L, Chen G, Zheng Y, Xiong J, Wang Z, Duong DM, Zhang Z, Cao X, Wang T, Tang L, Ye K, Zhang Z., Free PMC Article | 10/23/2021 |
| AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway. | AMPH1 functions as a tumour suppressor in ovarian cancer via the inactivation of PI3K/AKT pathway.
Chen Y, Cao W, Wang L, Zhong T., Free PMC Article | 05/1/2021 |
| the anti-oncogenic function of AMPH-1 in lung cancer in vitro and in vivo, is reported. | AMPH-1 is a tumor suppressor of lung cancer by inhibiting Ras-Raf-MEK-ERK signal pathway.
Yang H, Wan Z, Huang C, Yin H, Song D. | 05/4/2019 |
| The data show that the dynamin-amphiphysin helices are rearranged to form clusters upon GTP hydrolysis and membrane constriction occurs at protein-uncoated regions flanking the clusters. | Dynamic clustering of dynamin-amphiphysin helices regulates membrane constriction and fission coupled with GTP hydrolysis.
Takeda T, Kozai T, Yang H, Ishikuro D, Seyama K, Kumagai Y, Abe T, Yamada H, Uchihashi T, Ando T, Takei K., Free PMC Article | 09/1/2018 |
| We show that AMPH-1/BIN1 binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 in both species. We propose that BIN1 has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies. | Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton.
D'Alessandro M, Hnia K, Gache V, Koch C, Gavriilidis C, Rodriguez D, Nicot AS, Romero NB, Schwab Y, Gomes E, Labouesse M, Laporte J. | 02/13/2016 |
| It is a nerve protein and its autoantibody causes paraneoplastic neurological syndromes. | [Anti-amphiphysin antibody-positive paraneoplastic neurological syndrome with a longitudinally extensive spinal cord lesion of the dorsal column].
Neshige S, Hara N, Takeshima S, Iwaki H, Shimoe Y, Takamatsu K, Kuriyama M. | 04/18/2015 |
| AMPH1 protein level is reduced in transgenic mouse brain proteins. in the brainstem of nontransgenic and terminally ill JNPL3 transgenic mice. | Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration.
De Jesús-Cortés HJ, Nogueras-Ortiz CJ, Gearing M, Arnold SE, Vega IE., Free PMC Article | 07/20/2013 |
| We propose that antibody-mediated amphiphysin deficiency may account for anxiety behavior in stiff person syndrome | Human IgG directed against amphiphysin induces anxiety behavior in a rat model after intrathecal passive transfer.
Geis C, Grünewald B, Weishaupt A, Wultsch T, Toyka KV, Reif A, Sommer C. | 12/8/2012 |
| A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S. | 04/26/2012 |
| structure-based approach to prediction of peptide-binding behavior of SH3 domain of amphiphysin-1: statistical modeling | Toward quantitative characterization of the binding profile between the human amphiphysin-1 SH3 domain and its peptide ligands.
He P, Wu W, Wang HD, Yang K, Liao KL, Zhang W. | 08/2/2010 |
| investigation of binding affinities of decapeptide ligands with amphiphysin SH3 domain using QSAR models | Applying chemometrics approaches to model and predict the binding affinities between the human amphiphysin SH3 domain and its peptide ligands.
Liu L, He D, Yang S, Xu Y. | 07/5/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Analyses of Gaussian distribution models showed that diversified properties contribute to the interactions between the SH3 domain and of amphiphysin and peptides. | Modeling and prediction of binding affinities between the human amphiphysin SH3 domain and its peptide ligands using genetic algorithm-Gaussian processes.
Zhou P, Tian F, Chen X, Shang Z. | 01/21/2010 |
| This study demonstrates that the analysis of the molecular interaction energy components between peptides and the SH3 domain can successfully characterize the binding interface. | Characterization of domain-peptide interaction interface: a case study on the amphiphysin-1 SH3 domain.
Hou T, Zhang W, Case DA, Wang W. | 01/21/2010 |
| Female patient with amphiphysin autoantibodies and siff leg syndrome due to small cell cancer of the lung. | Antiamphiphysin-positive stiff-person syndrome associated with small cell lung cancer.
Nguyen-Huu BK, Urban PP, Schreckenberger M, Dieterich M, Werhahn KJ. | 01/21/2010 |
| Amphiphysin I (Amph I) is a minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase substrate. Amph I phosphorylation changes the recruitment of endophilin at the endocytic sites. | Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome.
Murakami N, Xie W, Lu RC, Chen-Hwang MC, Wieraszko A, Hwang YW. | 01/21/2010 |