| Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus. | Bisphenol-A inhibits mitochondrial biogenesis via impairment of GFER mediated mitochondrial protein import in the rat brain hippocampus.
Goyal S, Tiwari S, Seth B, Tandon A, Shankar J, Sinha M, Singh SJ, Priya S, Chaturvedi RK. | 01/29/2022 |
| our results demonstrate that Growth Factor Erv1-Like gene knock-down, i.e., the lack of Augmenter of Liver Regeneration, modifies the expression of genes involved in cell apoptosis and inhibits early phase of DNA synthesis. | Transient GFER knockdown in vivo impairs liver regeneration after partial hepatectomy.
Francavilla A, Pesetti B, Barone M, Morgano A, Bovenga F, Napoli A, Resta L, Russo F, Linsalata M, Minoia M, Bianco G, Tafaro A, Polimeno L. | 04/4/2015 |
| improves hepatocyte survival and promoted liver recovery after transplantation for acute liver failure | Augmenter of liver regeneration improves therapeutic effect of hepatocyte homotransplantation in acute liver failure rats.
Wang N, Wang Z, Sun H, Shi X, Zhang Y, Liu Q. | 09/14/2013 |
| ALR may serve as a potential diagnostic marker of hepatocellular stress and/or acute inflammatory conditions. | Augmenter of liver regeneration (ALR) is a novel biomarker of hepatocellular stress/inflammation: in vitro, in vivo and in silico studies.
Vodovotz Y, Prelich J, Lagoa C, Barclay D, Zamora R, Murase N, Gandhi CR., Free PMC Article | 05/11/2013 |
| ALR level in serum may indicate hepatocyte proliferation or liver regeneration. High ALR level in serum in early stage of acute-on-chrinic liver failure may mean a good prognosis. | Augmenter of liver regeneration may be a candidate for prognosis of HBV related acute-on-chronic liver failure as a regenerative marker.
Hongbo S, Yu C, Ming K, Honglin S, Ping HY, Ping DZ. | 12/22/2012 |
| Loss of augmenter of liver regeneration is associated with renal dysfunction in ischaemia/reperfusion injury. | Augmenter of liver regeneration protects kidneys from ischaemia/reperfusion injury in rats.
Liao XH, Zhang L, Liu Q, Sun H, Peng CM, Guo H. | 01/1/2011 |
| effectively accelerates kidney recovery after acute renal failure induced by gentamicin; the protective effect is associated with enhanced proliferation of renal tubular cells | Expression of augmenter of liver regeneration in rats with gentamicin-induced acute renal failure and its protective effect on kidney.
Liao XH, Zhang L, Tang XP, Liu Q, Sun H. | 04/12/2010 |
| Demonstrate specific G-protein coupled binding of ALR and its function in Kupffer cells and suggest that mediators produced by ALR-stimulated Kupffer cells may elicit physiologically important effects on hepatocytes. | Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells.
Gandhi CR, Murase N, Starzl TE., Free PMC Article | 01/21/2010 |
| Demonstrate that Alrp improves SH-SY5Y cells survival in H(2)O(2)-induced apoptosis. | Protective effect of augmenter of liver regeneration on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells.
Polimeno L, Pesetti B, Lisowsky T, Iannone F, Resta L, Giorgio F, Mallamaci R, Buttiglione M, Santovito D, Vitiello F, Mancini ME, Francavilla A. | 01/21/2010 |
| review of the molecular biology of ALR [review] | Insights on augmenter of liver regeneration cloning and function.
Gatzidou E, Kouraklis G, Theocharis S., Free PMC Article | 01/21/2010 |
| Data show that augmenter of liver regeneration factor (ALR) can promote hepatocyte proliferation induced by Kupffer cells, suggesting that Kupffer cells play a dual role in liver regeneration. | Augmenter of liver regeneration promotes hepatocyte proliferation induced by Kupffer cells.
Wang CP, Zhou L, Su SH, Chen Y, Lu YY, Wang F, Jia HJ, Feng YY, Yang YP., Free PMC Article | 01/21/2010 |
| crystal structure of ALR has been determined to 1.8 A, and possible physiological roles of ALR are examined | The crystal structure of augmenter of liver regeneration: A mammalian FAD-dependent sulfhydryl oxidase.
Wu CK, Dailey TA, Dailey HA, Wang BC, Rose JP., Free PMC Article | 01/21/2010 |