| Fetuin-B Overexpression Promotes Inflammation in Diabetic Retinopathy Through Activating Microglia and the NF-kappaB Signaling Pathway. | Fetuin-B Overexpression Promotes Inflammation in Diabetic Retinopathy Through Activating Microglia and the NF-κB Signaling Pathway.
Zhang W, Yao J, Chen C, Wang J, Zhou A. | 02/1/2024 |
| Hepatokine Fetuin B expression is regulated by leptin-STAT3 signalling and associated with leptin in obesity. | Hepatokine Fetuin B expression is regulated by leptin-STAT3 signalling and associated with leptin in obesity.
Wang D, Wu M, Zhang X, Li L, Lin M, Shi X, Zhao Y, Huang C, Li X., Free PMC Article | 08/6/2022 |
| Association of Fetuin-B with Subclinical Atherosclerosis in Obese Chinese Adults. | Association of Fetuin-B with Subclinical Atherosclerosis in Obese Chinese Adults.
Li Z, He C, Liu Y, Wang D, Lin M, Liu C, Shi X, Chen Z, Li X, Yang S, Li W., Free PMC Article | 04/24/2021 |
| Fetuin-B regulates vascular plaque rupture via TGF-beta receptor-mediated Smad pathway in vascular smooth muscle cells. | Fetuin-B regulates vascular plaque rupture via TGF-β receptor-mediated Smad pathway in vascular smooth muscle cells.
Jung SH, Lee D, Jin H, Lee HM, Ko HM, Lee KJ, Kim SJ, Ryu Y, Choi WS, Kim B, Won KJ. | 04/17/2021 |
| Fetuin B overexpression suppresses proliferation, migration, and invasion in prostate cancer by inhibiting the PI3K/AKT signaling pathway. | Fetuin B overexpression suppresses proliferation, migration, and invasion in prostate cancer by inhibiting the PI3K/AKT signaling pathway.
Zhan K, Liu R, Tong H, Gao S, Yang G, Hossain A, Li T, He W. | 02/20/2021 |
| The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases. | The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases.
Guevara T, Körschgen H, Cuppari A, Schmitz C, Kuske M, Yiallouros I, Floehr J, Jahnen-Dechent W, Stöcker W, Gomis-Rüth FX., Free PMC Article | 10/31/2020 |
| Serum fetuin-B level is an independent marker for nonalcoholic fatty liver disease in patients with type 2 diabetes. | Serum fetuin-B level is an independent marker for nonalcoholic fatty liver disease in patients with type 2 diabetes.
El-Ashmawy HM, Ahmed AM. | 09/12/2020 |
| Serum fetuin-B level is correlated with fertilization rate in conventional IVF and it may be used as a predictive marker of fertilization in IVF treatment. | Serum and follicular fluid fetuin-B levels are correlated with fertilization rates in conventional IVF cycles.
Fang L, Hu X, Cui L, Lv P, Ma X, Ye Y., Free PMC Article | 12/14/2019 |
| High Fetuin B expression is associated with vitamin D deficiency and pediatric obesity. | Fetuin B links vitamin D deficiency and pediatric obesity: Direct negative regulation by vitamin D.
Walker GE, Follenzi A, Bruscaggin V, Manfredi M, Bellone S, Marengo E, Maiuri L, Prodam F, Bona G., Free PMC Article | 08/24/2019 |
| Fetuin-B links nonalcoholic fatty liver disease (NAFLD) to type 2 diabetes (T2D) via inducing insulin resistance, and NAFLD contributes to the pathogenesis of T2D via multiple mechanisms. | Fetuin-B links nonalcoholic fatty liver disease to type 2 diabetes via inducing insulin resistance: Association and path analyses.
Li Z, Lin M, Liu C, Wang D, Shi X, Chen Z, Liu Y, Yang S, Li X. | 08/3/2019 |
| Fetuin B serum concentrations are not significantly different between patients with lipodystrophy (LD) and non-LD controls. | Serum concentrations of fetuin B in lipodystrophic patients.
Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll M, Fasshauer M. | 05/4/2019 |
| Patients with type 2 diabetes have significantly higher concentrations of plasma fetuin-B compared with normal glucose tolerance subjects and plasma fetuin-B is strongly associated with glucose and lipid metabolism, chronic inflammation and first-phase glucose-stimulated insulin secretion and insulin resistance. | Plasma fetuin-B concentrations are associated with insulin resistance and first-phase glucose-stimulated insulin secretion in individuals with different degrees of glucose tolerance.
Qu H, Qiu Y, Wang Y, Liao Y, Zheng Y, Zheng H. | 03/9/2019 |
| Fetuin-A can alter insulin signaling and that fetuin-B may regulate glucose homeostasis via so far unknown effects, possibly on glucose effectiveness. | The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans.
Peter A, Kovarova M, Staiger H, Machann J, Schick F, Königsrainer A, Königsrainer I, Schleicher E, Fritsche A, Häring HU, Stefan N. | 02/23/2019 |
| Carrying the minor G allele for FETUB rs4686434 was significantly associated with decreased intrahepatic triglyceride content and may affect hepatic triglyceride accumulation in individuals at high risk of non-alcoholic fatty liver disease. | The rs4686434 variant in the fetuin B (FETUB) locus is associated with intrahepatic triglyceride content in obese Chinese adults.
Li Z, Lin M, Liu C, Chen Z, Wang D, Shi X, Yang S, Li XJ. | 02/2/2019 |
| High Serum fetuin-B expression is associated with insulin resistance. | Serum fetuin-B is positively associated with intrahepatic triglyceride content and increases the risk of insulin resistance in obese Chinese adults: A cross-sectional study.
Wang D, Liu Y, Liu S, Lin L, Liu C, Shi X, Chen Z, Lin M, Yang S, Li Z, Li X. | 10/20/2018 |
| fetuin B may serve as a potential biomarker for coronary artery disease | Increased serum levels of fetuin B in patients with coronary artery disease.
Zhu K, Wang Y, Shu P, Zhou Q, Zhu J, Zhou W, Du C, Xu C, Liu X, Tang L. | 08/4/2018 |
| Increased serum fetuin-B level was significantly associated with higher risk of insulin resistance. Common genetic variants of FETUB SNPs (rs4686434, rs6785067, and rs3733159) were significantly associated with serum fetuin-B concentrations but were not associated with insulin resistance. | Common genetic variants in the FETUB locus, genetically predicted fetuin-B levels, and risk of insulin resistance in obese Chinese adults.
Li Z, Liu C, Shi X, Chen Z, Wang D, Li L, Tu Y, Lin M, Liu S, Yang S, Li X., Free PMC Article | 02/17/2018 |
| serum level of fetuin B in the control subjects was lower than it in nonalcoholic fatty liver disease patients. fetuin B correlated with diastolic blood pressure, serum alanine transaminase and triglycerides, among the controls. It suggested a potential association between serum fetuin B and the presence of NAFLD. | Serum fetuin B level increased in subjects of nonalcoholic fatty liver disease: a case-control study.
Zhu J, Wan X, Wang Y, Zhu K, Li C, Yu C, Li Y. | 09/30/2017 |
| Further studies need to elucidate factors contributing to fetuin B regulation in humans, as well as the pathophysiological significance of fetuin B upregulation in gestational diabetes | Regulation of the novel adipokines/ hepatokines fetuin A and fetuin B in gestational diabetes mellitus.
Kralisch S, Hoffmann A, Lössner U, Kratzsch J, Blüher M, Stumvoll M, Fasshauer M, Ebert T. | 05/27/2017 |
| Data indicate that fetuin-B was one of the highly expressed serum proteins in acute myocardial infarction. | The serum protein fetuin-B is involved in the development of acute myocardial infarction.
Jung SH, Won KJ, Lee KP, Kim HJ, Seo EH, Lee HM, Park ES, Lee SH, Kim B. | 07/25/2015 |
| Reduced expression of fetuin-b led to a significant increase in the expression of lipogenic genes, thereby resulting in higher lipid levels. | Downregulation of fetuin-B and zinc-α2-glycoprotein is linked to impaired fatty acid metabolism in liver cells.
Choi JW, Liu H, Mukherjee R, Yun JW. | 11/24/2012 |
| results support the hypothesis that fetuin-A serum levels are associated with bone cell activity | Renal osteodystrophy: alpha-Heremans Schmid glycoprotein/fetuin-A, matrix GLA protein serum levels, and bone histomorphometry.
Coen G, Ballanti P, Balducci A, Grandi F, Manni M, Mantella D, Pierantozzi A, Ruggeri M, Sardella D, Sorbo G, Bonucci E. | 01/21/2010 |
| serum fetuin has a role in processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells | Processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells: evidence for an uptake mechanism for serum fetuin.
Wajih N, Borras T, Xue W, Hutson SM, Wallin R. | 01/21/2010 |