| DNA methylation of Ad4BP/SF-1 suppresses Cyp11a1 and StAR transcripts in C2C12 myoblasts. | DNA methylation of Ad4BP/SF-1 suppresses Cyp11a1 and StAR transcripts in C2C12 myoblasts.
Fujiki J, Maeda N, Yamaguchi K, Ohtsuki Y, Iwano H. | 09/23/2024 |
| The transcription factors NR5A1 and JUNB cooperate to activate the Axl promoter in mouse Sertoli cell lines. | The transcription factors NR5A1 and JUNB cooperate to activate the Axl promoter in mouse Sertoli cell lines.
Diawara M, Martin LJ. | 09/23/2024 |
| Conditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development. | Conditional disruption of Nr5a1 directed by Sox9-Cre impairs adrenal development.
Tagami A, Ikeda Y, Ishizuka K, Maekawa M., Free PMC Article | 06/6/2024 |
| Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis. | Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis.
Souali-Crespo S, Condrea D, Vernet N, Féret B, Klopfenstein M, Grandgirard E, Alunni V, Cerciat M, Jung M, Mayere C, Nef S, Mark M, Chalmel F, Ghyselinck NB., Free PMC Article | 12/18/2023 |
| Trps1 acts as a regulator of Sf-1 transcription and testosterone synthesis in mouse Leydig cells. | Trps1 acts as a regulator of Sf-1 transcription and testosterone synthesis in mouse Leydig cells.
Sun J, Lian X, Lv C, Li H, Lin Z, Luo S, Liu Y, Xu Y, Jiang X, Xu W, Liao S, Chen Z, Wang S. | 12/5/2023 |
| Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus. | Inhibition of high-fat diet-induced inflammatory responses in adipose tissue by SF1-expressing neurons of the ventromedial hypothalamus.
Rashid M, Kondoh K, Palfalvi G, Nakajima KI, Minokoshi Y. | 10/13/2023 |
| Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model. | Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model.
Shima Y, Miyabayashi K, Mori T, Ono K, Kajimoto M, Cho HL, Tsuchida H, Uenoyama Y, Tsukamura H, Suzuki K, Choi MH, Toida K., Free PMC Article | 01/14/2023 |
| The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice. | The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice.
Smith OE, Morin F, Roussel V, Bertucci MC, Boyer A, Murphy BD. | 12/10/2022 |
| Steroidogenic Factor 1 Regulates Transcription of the Inhibin B Coreceptor in Pituitary Gonadotrope Cells. | Steroidogenic Factor 1 Regulates Transcription of the Inhibin B Coreceptor in Pituitary Gonadotrope Cells.
Lin YF, Schang G, Buddle ERS, Schultz H, Willis TL, Ruf-Zamojski F, Zamojski M, Mendelev N, Boehm U, Sealfon SC, Andoniadou CL, Bernard DJ., Free PMC Article | 10/22/2022 |
| Steroidogenic Factor 1 Regulation of the Hypothalamic-Pituitary-Ovarian Axis of Adult Female Mice. | Steroidogenic Factor 1 Regulation of the Hypothalamic-Pituitary-Ovarian Axis of Adult Female Mice.
Smith OE, Roussel V, Morin F, Ongaro L, Zhou X, Bertucci MC, Bernard DJ, Murphy BD., Free PMC Article | 04/16/2022 |
| Crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland. | In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland.
Buaas FW, Gardiner JR, Clayton S, Val P, Swain A., Free PMC Article | 03/30/2022 |
| Data suggest that Sf1 and c-jun interact and cooperate to activate the Fdx1 promoter in MA-10 (tumorigenic cell line) and TM3 (non-tumorigenic cell line) Leydig cells; such activation requires different regulatory elements located between -124 and -306 bp of Fdx1 promoter and involves recruitment of Sf1 to this region. | Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.
Roumaud P, Rwigemera A, Martin LJ. | 03/30/2022 |
| Data indicate that the inhibin-alpha promoter is activated synergistically by Wt1 and Sf1. | Expression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells.
Ji SY, Hao JX, Li L, Zhang J, Zheng QS, Li XX, Wang XN, Han CS, Gao F, Liu YX., Free PMC Article | 03/30/2022 |
| The results of the current study show that EB treatment from P25 to P36 could not restore the number of kisspeptin-ir cells in the AVPV in agonadal SF-1 KO mice to numbers found in gonadally intact WT or EB-treated WT/OVX females | The Influence of Gonadal Steroid Hormones on Immunoreactive Kisspeptin in the Preoptic Area and Arcuate Nucleus of Developing Agonadal Mice with a Genetic Disruption of Steroidogenic Factor 1.
Büdefeld T, Tobet SA, Majdic G., Free PMC Article | 03/30/2022 |
| SF1 directly contributes to the abnormal uterine gland morphogenesis. | Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis.
Vasquez YM, Wu SP, Anderson ML, Hawkins SM, Creighton CJ, Ray M, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ., Free PMC Article | 03/30/2022 |
| SF1 in the ventromedial nucleus of the hypothalamus regulates age-dependent obesity. | Steroidogenic Factor 1 in the Ventromedial Nucleus of the Hypothalamus Regulates Age-Dependent Obesity.
Kinyua AW, Yang DJ, Chang I, Kim KW., Free PMC Article | 03/30/2022 |
| Defective autophagy in Sf1 neurons perturbs the metabolic response to fasting and causes mitochondrial dysfunction. | Defective autophagy in Sf1 neurons perturbs the metabolic response to fasting and causes mitochondrial dysfunction.
Coupé B, Leloup C, Asiedu K, Maillard J, Pénicaud L, Horvath TL, Bouret SG., Free PMC Article | 02/5/2022 |
| The conditional deletion of steroidogenic factor 1 (Nr5a1) in Sox9-Cre mice compromises testis differentiation. | The conditional deletion of steroidogenic factor 1 (Nr5a1) in Sox9-Cre mice compromises testis differentiation.
Ikeda Y, Tagami A, Maekawa M, Nagai A., Free PMC Article | 12/11/2021 |
| Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise. | Deletion of growth hormone receptor in hypothalamic neurons affects the adaptation capacity to aerobic exercise.
Pedroso JAB, Dos Santos LBP, Furigo IC, Spagnol AR, Wasinski F, List EO, Kopchick JJ, Donato J Jr., Free PMC Article | 12/11/2021 |
| Loss of CREB Coactivator CRTC1 in SF1 Cells Leads to Hyperphagia and Obesity by High-fat Diet But Not Normal Chow Diet. | Loss of CREB Coactivator CRTC1 in SF1 Cells Leads to Hyperphagia and Obesity by High-fat Diet But Not Normal Chow Diet.
Matsumura S, Ishikawa F, Sasaki T, Terkelsen MK, Ravnskjaer K, Jinno T, Tanaka J, Goto T, Inoue K., Free PMC Article | 11/27/2021 |
| Coordination of Multiple Cellular Processes by NR5A1/Nr5a1. | Coordination of Multiple Cellular Processes by NR5A1/Nr5a1.
Morohashi KI, Inoue M, Baba T., Free PMC Article | 09/18/2021 |
| Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice. | Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.
Rotgers E, Nicol B, Rodriguez K, Rattan S, Flaws JA, Yao HH., Free PMC Article | 08/7/2021 |
| EHD3 positively regulated by NR5A1 participates in testosterone synthesis via endocytosis. | EHD3 positively regulated by NR5A1 participates in testosterone synthesis via endocytosis.
Zhang L, Ding L, Li Y, Zhang F, Xu Y, Pan H, Wan X, Yan G, Yu F, Li R. | 07/10/2021 |
| CXCR4-SF1 bifunctional adipose-derived stem cells benefit for the treatment of Leydig cell dysfunction-related diseases. | CXCR4-SF1 bifunctional adipose-derived stem cells benefit for the treatment of Leydig cell dysfunction-related diseases.
Li X, Xu A, Li K, Zhang J, Li Q, Zhao G, Zhang Y, Yuan H, Guo Y, Lin P, Huang L., Free PMC Article | 05/8/2021 |
| Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination. | Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination.
Anamthathmakula P, Miryala CSJ, Moreci RS, Kyathanahalli C, Hassan SS, Condon JC, Jeyasuria P., Free PMC Article | 11/21/2020 |