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    Atp1b1 ATPase Na+/K+ transporting subunit beta 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25650, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Mechanism of Na-K-ATPase Inhibition by PGE2 in Intestinal Epithelial Cells.

    Mechanism of Na-K-ATPase Inhibition by PGE2 in Intestinal Epithelial Cells.
    Nepal N, Arthur S, Haynes J, Palaniappan B, Sundaram U., Free PMC Article

    10/23/2021
    Decreased content of the glycosylated form of Atp1b1 occurs in the renal tissue of irradiated rats.

    Alteration of renal Na,K-ATPase in rats following the mediastinal γ-irradiation.
    Kaločayová B, Kovačičová I, Radošinská J, Tóthová Ľ, Jagmaševič-Mézešová L, Fülöp M, Slezák J, Babál P, Janega P, Vrbjar N., Free PMC Article

    04/25/2020
    Ngb upregulation in CA1 after hypoxic postconditioning maintained the membranous level of Atp1b1 through Ngb-Atp1b1 interaction.

    Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of Na(+)/K(+) ATPases.
    Wen H, Liu L, Zhan L, Liang D, Li L, Liu D, Sun W, Xu E., Free PMC Article

    11/30/2019
    Data show that Na(+)/K(+)-ATPase's DR-region specific monoclonal antibody and direct activator DRm217 increased Na(+)/K(+)-ATPase activity and alleviated Ca(2+) level.

    Activation of Na+/K+-ATPase attenuates high glucose-induced H9c2 cell apoptosis via suppressing ROS accumulation and MAPKs activities by DRm217.
    Yan X, Xun M, Li J, Wu L, Dou X, Zheng J.

    03/4/2017
    Amino acid region (198-207) is crucial for both trans-dimerization of the Na+/K+-ATPase beta1 subunits and cell-to-cell adhesion.

    Identification of the amino acid region involved in the intercellular interaction between the β1 subunits of Na+/K+ -ATPase.
    Tokhtaeva E, Sachs G, Sun H, Dada LA, Sznajder JI, Vagin O., Free PMC Article

    02/16/2013
    interactions between the beta subunits of neighboring cells maintain integrity of intercellular junctions

    Epithelial junctions depend on intercellular trans-interactions between the Na,K-ATPase β₁ subunits.
    Tokhtaeva E, Sachs G, Souda P, Bassilian S, Whitelegge JP, Shoshani L, Vagin O., Free PMC Article

    09/17/2011
    analysis of pathways for maturation of the Na,K-ATPase beta1 and beta2 subunits in the endoplasmic reticulum

    Diverse pathways for maturation of the Na,K-ATPase β1 and β2 subunits in the endoplasmic reticulum of Madin-Darby canine kidney cells.
    Tokhtaeva E, Sachs G, Vagin O., Free PMC Article

    01/15/2011
    Data demonstrate that Na(+),K(+)-ATPase beta 1 subunits have sufficient proximity and affinity to permit a direct interaction, without requiring any additional extracellular molecules to span the distance.

    The polarized distribution of Na+,K+-ATPase: role of the interaction between {beta} subunits.
    Padilla-Benavides T, Roldán ML, Larre I, Flores-Benitez D, Villegas-Sepúlveda N, Contreras RG, Cereijido M, Shoshani L., Free PMC Article

    01/1/2011
    the ER quality control system allows export only of assembled alpha-beta complexes to the Golgi, whereas the number of alpha(1) subunits in the ER determines the amount of the alpha-beta complexes

    Assembly with the Na,K-ATPase alpha(1) subunit is required for export of beta(1) and beta(2) subunits from the endoplasmic reticulum.
    Tokhtaeva E, Sachs G, Vagin O., Free PMC Article

    01/21/2010
    Spermidine induction of Atp1b1 in small intestine may be mediated by altered ornithine decarboxylase expression.

    Oral polyamine administration modifies the ontogeny of hexose transporter gene expression in the postnatal rat intestine.
    Wild GE, Searles LE, Koski KG, Drozdowski LA, Begum-Hasan J, Thomson AB.

    01/21/2010
    beta(1)-Na(+),K(+)-ATPase is likely to represent the most physiologic and efficient subunit for HKalpha(2) assembly in distal colon.

    The effect of beta-subunit assembly on function and localization of the colonic H+,K+-ATPase alpha-subunit.
    Li J, Codina J, Petroske E, Werle MJ, Willingham MC, DuBose TD Jr.

    01/21/2010
    FXYD7 decreases the apparent K(+) affinity of rat alpha 1-beta 1 and alpha 2-beta 1, but not of alpha 3-beta1 isozymes.

    FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes.
    Béguin P, Crambert G, Monnet-Tschudi F, Uldry M, Horisberger JD, Garty H, Geering K., Free PMC Article

    01/21/2010
    Chronic heart failure-induced alterations in skeletal muscle Na(+)-K(+)-ATPase, including B(max) and isoform expression, can be partially reversed by exercise training.

    Training-induced changes in skeletal muscle Na+-K+ pump number and isoform expression in rats with chronic heart failure.
    Helwig B, Schreurs KM, Hansen J, Hageman KS, Zbreski MG, McAllister RM, Mitchell KE, Musch TI.

    01/21/2010
    glucocorticoids directly stimulate transcription of Na+-K+-ATPase beta1 gene expression in adult rat lung epithelial cells through a GR-dependent mechanism that can act at multiple sites.

    Dexamethasone stimulates transcription of the Na+-K+-ATPase beta1 gene in adult rat lung epithelial cells.
    Hao H, Wendt CH, Sandhu G, Ingbar DH.

    01/21/2010
    expression of Na/K ATPase beta1 subunit mRNA was transiently increased in astrocytes after reoxygenation, whereas hypoxia itself did not induce any gene expression change

    Induction of mRNAs and proteins for Na/K ATPase alpha1 and beta1 subunits following hypoxia/reoxygenation in astrocytes.
    Kasai K, Yamashita T, Yamaguchi A, Yoshiya K, Kawakita A, Tanaka H, Sugimoto H, Tohyama M.

    01/21/2010
    after an ischaemic, insult alpha1 and beta1 protein subunit abundance and mRNA levels are independently regulated.

    Evolution of renal function and Na+, K +-ATPase expression during ischaemia-reperfusion injury in rat kidney.
    Molinas SM, Trumper L, Serra E, Elías MM.

    01/21/2010
    the 143-nt segment in the distal segment of the 3'-UTR of beta1 mRNA may play an important role in the control of beta1-subunit expression.

    Control of Na+-K+-ATPase beta 1-subunit expression: role of 3'-untranslated region.
    Shao Y, Ismail-Beigi F.

    01/21/2010
    the the TM domain of FXYD7 has a role in mediating the complex interactions of FXYD7 with Na,K-ATPase

    Role of the transmembrane domain of FXYD7 in structural and functional interactions with Na,K-ATPase.
    Li C, Crambert G, Thuillard D, Roy S, Schaer D, Geering K.

    01/21/2010
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