| that MARCKS is involved in oligodendrocyte precursor cell maturation by interacting with Ras-associated protein 10 | MARCKS is Necessary for Oligodendrocyte Precursor Cell Maturation.
Zhang ZH, Ma FF, Zhang H, Xu XH. | 08/11/2018 |
| Either genetic silencing of MARCKS or disruption of its interaction with Rab10 inhibited axon growth of cortical neurons. | MARCKS regulates membrane targeting of Rab10 vesicles to promote axon development.
Xu XH, Deng CY, Liu Y, He M, Peng J, Wang T, Yuan L, Zheng ZS, Blackshear PJ, Luo ZG., Free PMC Article | 12/27/2014 |
| decreased MARCKS and pMARCKS in the frontal cortex in schizophrenia was found; results suggest a mechanism other than myristoylation was responsible for decreased MARCKS expression in schizophrenia | Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia.
Pinner AL, Haroutunian V, Meador-Woodruff JH., Free PMC Article | 11/29/2014 |
| In spermatozoa, as in chromatoid body, BASP1 and MARCKS may bind Ca(2+)-calmodulin and therefore contribute to the activation of calcium-dependent biochemical processes. | Immunoelectron microscopic study of BASP1 and MARCKS location in the early and late rat spermatids.
Mosevitsky MI, Snigirevskaya ES, Komissarchik YY. | 06/23/2012 |
| MARCKS phosphorylation via the activation of PKCdelta, which is downstream of PKA activation, is involved in the cAMP-dependent amylase release in parotid acinar cells. | Phosphorylation of myristoylated alanine-rich C kinase substrate is involved in the cAMP-dependent amylase release in parotid acinar cells.
Satoh K, Matsuki-Fukushima M, Qi B, Guo MY, Narita T, Fujita-Yoshigaki J, Sugiya H. | 01/21/2010 |
| These findings demonstrate a critical role for MARCKS-phosphatidylinositol-4,5-diphosphate signaling in regulating dendrite development. | Actin filament assembly by myristoylated alanine-rich C kinase substrate-phosphatidylinositol-4,5-diphosphate signaling is critical for dendrite branching.
Li H, Chen G, Zhou B, Duan S., Free PMC Article | 01/21/2010 |
| NMDA-induced dendritic spine collapse involves cathepsin B-like proteolysis of MARCKS | Cathepsin B-like proteolysis and MARCKS degradation in sub-lethal NMDA-induced collapse of dendritic spines.
Graber S, Maiti S, Halpain S. | 01/21/2010 |
| Prion proteins are isolated from neuronal cells, along with Marcks and fyn. | Immunoseparation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells.
Botto L, Masserini M, Cassetti A, Palestini P. | 01/21/2010 |
| These results suggest that intact phosphorylation sites within the MARCKS ED are required for PLD activation and influence both membrane-cytoskeletal organization and cell viability. | Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells.
Morash SC, Douglas D, McMaster CR, Cook HW, Byers DM. | 01/21/2010 |
| These results suggest that MARCKS is a target of PKG, and PKG-dependent phosphorylation of MARCKS results in its degradation to reduce its protein levels in the cells. | cGMP-dependent phosphorylation and degradation of myristoylated alanine-rich C-kinase substrate.
Matsubara T, Okumura N, Okumura A, Nagai K. | 01/21/2010 |
| MARCKS is involved in regulating growth cone adhesion as follows: its nonphosphorylated form stabilizes integrin-mediated adhesions, and its phosphorylation-triggered release from adhesions causes localized growth cone detachment. | Myristoylated, alanine-rich C-kinase substrate phosphorylation regulates growth cone adhesion and pathfinding.
Gatlin JC, Estrada-Bernal A, Sanford SD, Pfenninger KH., Free PMC Article | 01/21/2010 |
| Competitive interactions of Ca2+/calmodulin and MacMARCKS with mGluR7 control the tonic inhibition of voltage-sensitive Ca2+ channels. | MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels.
Bertaso F, Lill Y, Airas JM, Espeut J, Blahos J, Bockaert J, Fagni L, Betz H, El-Far O. | 01/21/2010 |
| Membrane-bound MARCKS but not total or cytosolic MARCKS was significantly reduced in the hippocampus of stressed rats; chronic lithium treatment reduced hippocampal MARCKS expression without affecting stress-induced reduction in membrane MARCKS | Differential expression and regulation of myristoylated alanine-rich C kinase substrate (MARCKS) in the hippocampus of C57/BL6J and DBA/2J mice.
McNamara RK, Vasquez PA, Mathe AA, Lenox RH. | 01/21/2010 |