| Mechanistic role of RND3-regulated IL33/ST2 signaling on cardiomyocyte senescence. | Mechanistic role of RND3-regulated IL33/ST2 signaling on cardiomyocyte senescence.
Wu L, Zhu X, Luo C, Zhao Y, Pan S, Shi K, Chen Y, Qiu J, Shen Z, Guo J, Jie W. | 05/29/2024 |
| Electroacupuncture prevents the development or establishment of chronic pain via IL-33/ST2 signaling in hyperalgesic priming model rats. | Electroacupuncture prevents the development or establishment of chronic pain via IL-33/ST2 signaling in hyperalgesic priming model rats.
Jin Y, Zhou J, Fang Y, Song H, Lin S, Pan B, Liu L, Xiong B. | 01/29/2024 |
| Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats. | Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats.
Sitzia C, Vianello E, Dozio E, Kalousová M, Zima T, Brizzola S, Roccabianca P, Tedeschi G, Lamont J, Tacchini L, Corsi-Romanelli MM., Free PMC Article | 03/1/2023 |
| ST2 silencing aggravates ventricular remodeling and chronic heart failure in rats by mediating the IL-33/ST2 axis. | ST2 silencing aggravates ventricular remodeling and chronic heart failure in rats by mediating the IL-33/ST2 axis.
Zhao YN, Li H, Zhao C, Liu GH. | 10/2/2021 |
| MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells. | MicroRNA-547-5p-mediated interleukin-33/suppressor of tumorigenicity 2 signaling underlies the genesis and maintenance of neuropathic pain and is targeted by the therapy with bone marrow stromal cells.
Zhou J, Zhuang T, Ma P, Shan L, Sun XD, Gong S, Tao J, Yu XM, Jiang X., Free PMC Article | 06/5/2021 |
| he transcription factor Yy1 regulates sST2 expression, and repression of Yy1 by metformin results in lower levels of sST2 that are associated with favorable myocardial remodeling. The manipulation of YY1 or its co-repressor HDAC4 emerge as new targets to modulate ST2/IL33 signaling and prevent adverse cardiac remodeling. | Yin-Yang 1 transcription factor modulates ST2 expression during adverse cardiac remodeling post-myocardial infarction.
Asensio-Lopez MC, Lax A, Fernandez Del Palacio MJ, Sassi Y, Hajjar RJ, Januzzi JL, Bayes-Genis A, Pascual-Figal DA. | 06/20/2020 |
| Calycosin treatment markedly improved the aforementioned makers of renal injury and dysfunction, modulated IL33/ST2 signaling. | Renoprotective effect of calycosin in high fat diet-fed/STZ injected rats: Effect on IL-33/ST2 signaling, oxidative stress and fibrosis suppression.
Elsherbiny NM, Said E, Atef H, Zaitone SA. | 02/22/2020 |
| The lungs are a relevant source of sST2 in heart failure, shich may have implications for disease progression. | Pulmonary Production of Soluble ST2 in Heart Failure.
Pascual-Figal DA, Pérez-Martínez MT, Asensio-Lopez MC, Sanchez-Más J, García-García ME, Martinez CM, Lencina M, Jara R, Januzzi JL, Lax A. | 08/17/2019 |
| ST2/IL-33 signaling plays an important role in the development of radicular pain in lumbar disk herniation. | IL-33/ST2 signaling contributes to radicular pain by modulating MAPK and NF-κB activation and inflammatory mediator expression in the spinal cord in rat models of noncompressive lumber disk herniation.
Huang SJ, Yan JQ, Luo H, Zhou LY, Luo JG., Free PMC Article | 04/13/2019 |
| administration of sST2 significantly attenuated the severity of severe acute pancreatitis and associated cardiac damage, and the cardioprotective effect is associated with its anti-inflammatory action | Adenovirus-mediated overexpression of sST2 attenuates cardiac injury in the rat with severe acute pancreatitis.
Li L, Sun Z, Xu C, Wu J, Liu G, Cui H, Chen H. | 05/26/2018 |
| Study demonstrates that IL-33 and ST2 are highly expressed by various central nervous system (CNS) resident cells, and there was a change of the expression levels and patterns of both molecules in the CNS lesions of multiple sclerosis (MS)patients compared with healthy brain tissues. Furthermore, IL-33/ST2 signaling pathway may have its unique important function in the myelination process in the CNS compartment. | Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system.
Allan D, Fairlie-Clarke KJ, Elliott C, Schuh C, Barnett SC, Lassmann H, Linnington C, Jiang HR., Free PMC Article | 10/28/2017 |
| A strong relationship of IL-33/ST2 with natriuretic peptides and classical inflammatory mediators was observed in cardiac tissue. Expression of sST2 in cardiac, adipose and liver tissue decreased in obese rats compared with controls, suggesting an involvement for IL-33/ST2 system in molecular mechanisms of obesity. | Effects of obesity on IL-33/ST2 system in heart, adipose tissue and liver: study in the experimental model of Zucker rats.
Ragusa R, Cabiati M, Guzzardi MA, D'Amico A, Giannessi D, Del Ry S, Caselli C. | 08/12/2017 |
| these results demonstrated that ST2L translocation from the cytosol to the cell membranes of lung tissue and the down-expression of sST2 in both fractions can function as new biomarkers of (ventilator-induced lung injury. | Membrane translocation of IL-33 receptor in ventilator induced lung injury.
Yang SH, Lin JC, Wu SY, Huang KL, Jung F, Ma MC, Wang Hsu GS, Jow GM., Free PMC Article | 02/20/2016 |
| This is the first study demonstrating a deleterious role for sST2 in the vascular remodeling associated with obesity. | A role for soluble ST2 in vascular remodeling associated with obesity in rats.
Martínez-Martínez E, Miana M, Jurado-López R, Rousseau E, Rossignol P, Zannad F, Cachofeiro V, López-Andrés N., Free PMC Article | 07/26/2014 |
| Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling. | Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling.
Seki K, Sanada S, Kudinova AY, Steinhauser ML, Handa V, Gannon J, Lee RT. | 01/21/2010 |