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    Hmgb1 high mobility group box 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25459, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    METTL3 mediated ferroptosis in chondrocytes and promoted pain in KOA via HMGB1 m6A modification.

    METTL3 mediated ferroptosis in chondrocytes and promoted pain in KOA via HMGB1 m6A modification.
    Bao T, Liao T, Cai X, Lu B, Dai G, Pei S, Zhang Y, Li Y, Xu B.

    10/16/2024
    SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood-Brain Barrier Impairment After Cerebral Venous Thrombosis.

    SIRT1-Mediated HMGB1 Deacetylation Suppresses Neutrophil Extracellular Traps Related to Blood-Brain Barrier Impairment After Cerebral Venous Thrombosis.
    Mu S, Li Z, Lin L, Wang D, Yang F, Chen L, Xian L, Lin K, Lin Y, Ye D, Yang Y, Wei L, Xu Y, Wang S.

    07/22/2024
    Box A of HMGB1 Maintains the DNA Gap and Prevents DDR-induced Kidney Injury in D-galactose Induction Rats.

    Box A of HMGB1 Maintains the DNA Gap and Prevents DDR-induced Kidney Injury in D-galactose Induction Rats.
    Khumsri W, Payuhakrit W, Kongkaew A, Chattipakorn N, Chattipakorn S, Yasom S, Mutirangura A., Free PMC Article

    05/3/2024
    HMGB1 Mediates Inflammation-Induced DMT1 Increase and Dopaminergic Neurodegeneration in the Early Stage of Parkinsonism.

    HMGB1 Mediates Inflammation-Induced DMT1 Increase and Dopaminergic Neurodegeneration in the Early Stage of Parkinsonism.
    Liang T, Yang SX, Qian C, Du LD, Qian ZM, Yung WH, Ke Y.

    04/1/2024
    Suppression of microRNA-320 Induces Cerebral Protection Against Ischemia/Reperfusion Injury by Targeting HMGB1/NF-kappaB Axis.

    Suppression of microRNA-320 Induces Cerebral Protection Against Ischemia/Reperfusion Injury by Targeting HMGB1/NF-kappaB Axis.
    Liang S, Cao W, Zhuang Y, Zhang D, Du S, Shi H., Free PMC Article

    03/14/2024
    Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.

    Influences of microRNA-451 on the expression of HMGB1 in myocardial cells and its mechanism in ischemia-reperfusion injury.
    Qiu R, Zhang Y, Li J, Wu J, He R.

    02/1/2024
    Inhibition of HMGB1 Attenuates Spinal Cord Edema by Reducing the Expression of Na[+]-K[+]-Cl[-] Cotransporter-1 and Na[+]/H[+] Exchanger-1 in Both Astrocytes and Endothelial Cells After Spinal Cord Injury in Rats.

    Inhibition of HMGB1 Attenuates Spinal Cord Edema by Reducing the Expression of Na(+)-K(+)-Cl(-) Cotransporter-1 and Na(+)/H(+) Exchanger-1 in Both Astrocytes and Endothelial Cells After Spinal Cord Injury in Rats.
    Li M, Lv J, Wang Z, Wang L, Qin Z, Deng C, Liu J, Sun L., Free PMC Article

    12/6/2023
    Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.

    Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
    Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X.

    11/16/2023
    Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic Pain.

    Hmgb1 Silencing in the Amygdala Inhibits Pain-Related Behaviors in a Rat Model of Neuropathic Pain.
    Presto P, Ji G, Ponomareva O, Ponomarev I, Neugebauer V., Free PMC Article

    08/17/2023
    HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.

    HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.
    Zhang Q, Chen Y, Wang Q, Wang Y, Feng W, Chai L, Liu J, Li D, Chen H, Qiu Y, Shen N, Shi X, Xie X, Li M., Free PMC Article

    06/16/2023
    Activation of the NLRP3 inflammasome by HMGB1 through inhibition of the Nrf2/HO-1 pathway promotes bleomycin-induced pulmonary fibrosis after acute lung injury in rats.

    Activation of the NLRP3 inflammasome by HMGB1 through inhibition of the Nrf2/HO-1 pathway promotes bleomycin-induced pulmonary fibrosis after acute lung injury in rats.
    Huang Y, Wang A, Jin S, Liu F, Xu F.

    06/2/2023
    Downregulation of TRIM27 alleviates hypoxic-ischemic encephalopathy through inhibiting inflammation and microglia cell activation by regulating STAT3/HMGB1 axis.

    Downregulation of TRIM27 alleviates hypoxic-ischemic encephalopathy through inhibiting inflammation and microglia cell activation by regulating STAT3/HMGB1 axis.
    Wang C, Zhang P, Li Y, Wang X, Guo L, Li J, Jiao H.

    04/21/2023
    Regulatory mechanisms of HMGB1 and its receptors in polycystic ovary syndrome-driven gravid uterine inflammation.

    Regulatory mechanisms of HMGB1 and its receptors in polycystic ovary syndrome-driven gravid uterine inflammation.
    Hu M, Zhang Y, Lu Y, Han J, Guo T, Cui P, Brännström M, Shao LR, Billig H., Free PMC Article

    04/7/2023
    [MiR-340 mediates the involvement of high mobility group box 1 in the pathogenesis of liver fibrosis].

    [MiR-340 mediates the involvement of high mobility group box 1 in the pathogenesis of liver fibrosis].
    Li SL, Yi PP, Chen RC, Huang ZB, Hu XW, Fan XG.

    03/24/2023
    High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.

    High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats.
    Sun Y, Zhu X, Zhu K, Yu J, Cheng L, Hei M., Free PMC Article

    12/17/2022
    [Long noncoding RNA ZEB1-AS1 aggravates cerebral ischemia/reperfusion injury in rats through the HMGB1/TLR-4 signaling axis].

    [Long noncoding RNA ZEB1-AS1 aggravates cerebral ischemia/reperfusion injury in rats through the HMGB1/TLR-4 signaling axis].
    Wang J, Chen X, Sun L, Chen X, Li H, Xiong B, Wang H., Free PMC Article

    09/17/2022
    HMGB1/TLR4 induces autophagy and promotes neuroinflammation after intracerebral hemorrhage.

    HMGB1/TLR4 induces autophagy and promotes neuroinflammation after intracerebral hemorrhage.
    Lei C, Li Y, Zhu X, Li H, Chang X.

    08/20/2022
    HMGB1-NLRP3-P2X7R pathway participates in PM2.5-induced hippocampal neuron impairment by regulating microglia activation.

    HMGB1-NLRP3-P2X7R pathway participates in PM(2.5)-induced hippocampal neuron impairment by regulating microglia activation.
    Liu C, She Y, Huang J, Liu Y, Li W, Zhang C, Zhang T, Yu L.

    08/13/2022
    Glycyrrhizic Acid Attenuates the Inflammatory Response After Spinal Cord Injury by Inhibiting High Mobility Group Box-1 Protein Through the p38/Jun N-Terminal Kinase Signaling Pathway.

    Glycyrrhizic Acid Attenuates the Inflammatory Response After Spinal Cord Injury by Inhibiting High Mobility Group Box-1 Protein Through the p38/Jun N-Terminal Kinase Signaling Pathway.
    Wu Z, Wang Z, Xie Z, Zhu H, Li C, Xie S, Zhou W, Zhang Z, Li M.

    08/13/2022
    Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis <em>via</em> NF-kappaB signaling pathway.

    Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis <em>via</em> NF-κB signaling pathway.
    Li YY, Feng YP, Liu L, Ke J, Long X., Free PMC Article

    06/25/2022
    High-mobility group box chromosomal protein-1 deletion alleviates osteoporosis in OVX rat model via suppressing the osteoclastogenesis and inflammation.

    High-mobility group box chromosomal protein-1 deletion alleviates osteoporosis in OVX rat model via suppressing the osteoclastogenesis and inflammation.
    Yu H, Zhou W, Zhong Z, Qiu R, Chen G, Zhang P., Free PMC Article

    04/30/2022
    MiR-582-5p Attenuates Neonatal Hypoxic-ischemic Encephalopathy by Targeting High Mobility Group box 1 (HMGB1) through Inhibiting Neuroinflammation and Oxidative Stress.

    MiR-582-5p Attenuates Neonatal Hypoxic-ischemic Encephalopathy by Targeting High Mobility Group box 1 (HMGB1) through Inhibiting Neuroinflammation and Oxidative Stress.
    Yang G, Xue Z, Zhao Y.

    04/9/2022
    Magnesium sulfate reduces vascular endothelial cell apoptosis in rats with preeclampsia via the miR-218-5p/HMGB1 pathway.

    Magnesium sulfate reduces vascular endothelial cell apoptosis in rats with preeclampsia via the miR-218-5p/HMGB1 pathway.
    Zheng J, Tian M, Liu L, Jia X, Sun M, Lai Y.

    02/12/2022
    The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I-mediated necroptosis.

    The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I-mediated necroptosis.
    Raafat Ibrahim R, Shafik NM, El-Esawy RO, El-Sakaa MH, Arakeeb HM, El-Sharaby RM, Ali DA, Safwat El-Deeb O, Ragab Abd El-Khalik S., Free PMC Article

    02/5/2022
    Effect of serum high mobility group box 1 protein on immune function and autophagy level of myocardial cells in rats with sepsis.

    Effect of serum high mobility group box 1 protein on immune function and autophagy level of myocardial cells in rats with sepsis.
    Wu Y, Wang HB, Yang Y, Dong QL.

    01/8/2022
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