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    FUT8 fucosyltransferase 8 [ Homo sapiens (human) ]

    Gene ID: 2530, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    High-Throughput Mass Spectrometry Analysis of N-Glycans and Protein Markers after FUT8 Knockdown in the Syngeneic SW480/SW620 Colorectal Cancer Cell Model.

    High-Throughput Mass Spectrometry Analysis of N-Glycans and Protein Markers after FUT8 Knockdown in the Syngeneic SW480/SW620 Colorectal Cancer Cell Model.
    López-Cortés R, Muinelo-Romay L, Fernández-Briera A, Gil Martín E., Free PMC Article

    04/11/2024
    The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications.

    The Multifaceted Role of FUT8 in Tumorigenesis: From Pathways to Potential Clinical Applications.
    Shi M, Nan XR, Liu BQ., Free PMC Article

    02/28/2024
    Distinctive domains and activity regulation of core fucosylation enzyme FUT8.

    Distinctive domains and activity regulation of core fucosylation enzyme FUT8.
    Tomida S, Nagae M, Kizuka Y.

    02/24/2024
    A genetic variation in fucosyltransferase 8 accelerates HIV-1 disease progression indicating a role for N-glycan fucosylation.

    A genetic variation in fucosyltransferase 8 accelerates HIV-1 disease progression indicating a role for N-glycan fucosylation.
    van Pul L, Maurer I, Boeser-Nunnink BDM, Harskamp AM, van Dort KA, Kootstra NA., Free PMC Article

    11/1/2023
    Diagnosis and prognosis of serum Fut8 for epilepsy and refractory epilepsy in children.

    Diagnosis and prognosis of serum Fut8 for epilepsy and refractory epilepsy in children.
    Huang Y, Zhang Z, Chen L., Free PMC Article

    04/17/2023
    The Association of the Polymorphisms in the FUT8-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder.

    The Association of the Polymorphisms in the FUT8-Related Locus with the Plasma Glycosylation in Post-Traumatic Stress Disorder.
    Tudor L, Nedic Erjavec G, Nikolac Perkovic M, Konjevod M, Uzun S, Kozumplik O, Mimica N, Lauc G, Svob Strac D, Pivac N., Free PMC Article

    03/31/2023
    FUT8 is regulated by miR-122-5p and promotes malignancies in intrahepatic cholangiocarcinoma via PI3K/AKT signaling.

    FUT8 is regulated by miR-122-5p and promotes malignancies in intrahepatic cholangiocarcinoma via PI3K/AKT signaling.
    Chen F, Li Y, Aye L, Wu Y, Dong L, Yang Z, Gao Q, Zhang S.

    02/24/2023
    Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response.

    Fucosyltransferase 8 (FUT8) and core fucose expression in oxidative stress response.
    Kyunai YM, Sakamoto M, Koreishi M, Tsujino Y, Satoh A., Free PMC Article

    02/16/2023
    The stem region of alpha1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity.

    The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity.
    Tomida S, Nagae M, Kizuka Y., Free PMC Article

    01/14/2023
    SNHG1/miR-186/FUT8 regulates cell migration and invasion in oral squamous cell carcinoma.

    SNHG1/miR-186/FUT8 regulates cell migration and invasion in oral squamous cell carcinoma.
    Zhao Y, Shi J, Zhao Y, Lu Z.

    12/24/2022
    The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins.

    The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins.
    Cantero-Recasens G, Burballa C, Ohkawa Y, Fukuda T, Harada Y, IBD Character Consortium, Curwin AJ, Brouwers N, Thun GA, Gu J, Gut I, Taniguchi N, Malhotra V., Free PMC Article

    10/22/2022
    Involvement of the alpha-helical and Src homology 3 domains in the molecular assembly and enzymatic activity of human alpha1,6-fucosyltransferase, FUT8.

    Involvement of the α-helical and Src homology 3 domains in the molecular assembly and enzymatic activity of human α1,6-fucosyltransferase, FUT8.
    Ihara H, Okada T, Taniguchi N, Ikeda Y.

    06/18/2022
    LncRNA LEF1-AS1/LEF1/FUT8 Axis Mediates Colorectal Cancer Progression by Regulating alpha1, 6-Fucosylationvia Wnt/beta-Catenin Pathway.

    LncRNA LEF1-AS1/LEF1/FUT8 Axis Mediates Colorectal Cancer Progression by Regulating α1, 6-Fucosylationvia Wnt/β-Catenin Pathway.
    Qi Y, Shan Y, Li S, Huang Y, Guo Y, Huang T, Zhao X, Jia L.

    06/11/2022
    Fucosyltransferase 8 is Overexpressed and Influences Clinical Outcomes in Lung Adenocarcinoma Patients.

    Fucosyltransferase 8 is Overexpressed and Influences Clinical Outcomes in Lung Adenocarcinoma Patients.
    Liang Y, Wang T, Gao R, Jia X, Ji T, Shi P, Xue J, Yang A, Chen M, Han P., Free PMC Article

    03/26/2022
    cFUT8 promotes liver cancer progression by miR-548c/FUT8 axis.

    cFUT8 promotes liver cancer progression by miR-548c/FUT8 axis.
    Li C, Xin Z, He L, Ning J, Lin K, Pan J, Rao J, Wang G, Zhu H., Free PMC Article

    03/5/2022
    Up-regulation of FUT8 inhibits TGF-beta1-induced activation of hepatic stellate cells during liver fibrogenesis.

    Up-regulation of FUT8 inhibits TGF-β1-induced activation of hepatic stellate cells during liver fibrogenesis.
    Kuang M, Wu H, Hu L, Guo X, He D, Liu B, Chen M, Gu J, Gu J, Zeng X, Ruan Y.

    01/29/2022
    Appropriate aglycone modification significantly expands the glycan substrate acceptability of alpha1,6-fucosyltransferase (FUT8).

    Appropriate aglycone modification significantly expands the glycan substrate acceptability of α1,6-fucosyltransferase (FUT8).
    Zhang R, Yang Q, Boruah BM, Zong G, Li C, Chapla D, Yang JY, Moremen KW, Wang LX., Free PMC Article

    11/27/2021
    FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.

    FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.
    Kelel M, Yang RB, Tsai TF, Liang PH, Wu FY, Huang YT, Yang MF, Hsiao YP, Wang LF, Tu CF, Liu FT, Lee YL.

    10/9/2021
    alpha1,6-Fucosyltransferase contributes to cell migration and proliferation as well as to cancer stemness features in pancreatic carcinoma.

    α1,6-Fucosyltransferase contributes to cell migration and proliferation as well as to cancer stemness features in pancreatic carcinoma.
    Liang C, Fukuda T, Isaji T, Duan C, Song W, Wang Y, Gu J.

    09/11/2021
    Role of FUT8 expression in clinicopathology and patient survival for various malignant tumor types: a systematic review and meta-analysis.

    Role of FUT8 expression in clinicopathology and patient survival for various malignant tumor types: a systematic review and meta-analysis.
    Ma M, Han G, Wang Y, Zhao Z, Guan F, Li X., Free PMC Article

    09/4/2021
    Expanding the molecular and clinical phenotypes of FUT8-CDG.

    Expanding the molecular and clinical phenotypes of FUT8-CDG.
    Ng BG, Dastsooz H, Silawi M, Habibzadeh P, Jahan SB, Fard MAF, Halliday BJ, Raymond K, Ruzhnikov MRZ, Tabatabaei Z, Taghipour-Sheshdeh A, Brimble E, Robertson SP, Faghihi MA, Freeze HH., Free PMC Article

    08/28/2021
    Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2gamma.

    Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2γ.
    Ma M, Guo D, Tan Z, Du J, Guan F, Li X., Free PMC Article

    08/21/2021
    Impact of Increased FUT8 Expression on the Extracellular Vesicle Proteome in Prostate Cancer Cells.

    Impact of Increased FUT8 Expression on the Extracellular Vesicle Proteome in Prostate Cancer Cells.
    Clark DJ, Schnaubelt M, Hoti N, Hu Y, Zhou Y, Gooya M, Zhang H., Free PMC Article

    07/3/2021
    FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer.

    FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer.
    Huang Y, Zhang HL, Li ZL, Du T, Chen YH, Wang Y, Ni HH, Zhang KM, Mai J, Hu BX, Huang JH, Zhou LH, Yang D, Peng XD, Feng GK, Tang J, Zhu XF, Deng R., Free PMC Article

    06/5/2021
    A lectin-based glycomic approach identifies FUT8 as a driver of radioresistance in oesophageal squamous cell carcinoma.

    A lectin-based glycomic approach identifies FUT8 as a driver of radioresistance in oesophageal squamous cell carcinoma.
    Shen L, Xia M, Deng X, Ke Q, Zhang C, Peng F, Dong X, Luo Z.

    06/5/2021
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