| Aquaporin 1 is renoprotective in septic acute kidney injury by attenuating inflammation, apoptosis and fibrosis through inhibition of P53 expression. | Aquaporin 1 is renoprotective in septic acute kidney injury by attenuating inflammation, apoptosis and fibrosis through inhibition of P53 expression.
Lv W, Liao J, Li C, Liu D, Luo X, Diao R, Wang Y, Jin Y., Free PMC Article | 10/28/2024 |
| A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells. | A novel interaction between aquaporin 1 and caspase-3 in pulmonary arterial smooth muscle cells.
Niedermeyer S, Yun X, Trujillo M, Jiang H, Andrade MR, Kolb TM, Suresh K, Damarla M, Shimoda LA., | 05/23/2024 |
| Altered Expression of AQP1 and AQP4 in Brain Barriers and Cerebrospinal Fluid May Affect Cerebral Water Balance during Chronic Hypertension. | Altered Expression of AQP1 and AQP4 in Brain Barriers and Cerebrospinal Fluid May Affect Cerebral Water Balance during Chronic Hypertension.
González-Marrero I, Hernández-Abad LG, González-Gómez M, Soto-Viera M, Carmona-Calero EM, Castañeyra-Ruiz L, Castañeyra-Perdomo A., Free PMC Article | 11/5/2022 |
| Testicular AQP1 expression in a rat model of testicular Ischemia-Reperfusion injury. | Testicular AQP1 expression in a rat model of testicular Ischemia-Reperfusion injury.
Ablimit A, Abdureyim Z, Yang P, Azmat R, Shan W, Yao Q. | 08/21/2021 |
| Differential response of cardiac aquaporins to hyperosmotic stress; salutary role of AQP1 against the induced apoptosis. | Differential response of cardiac aquaporins to hyperosmotic stress; salutary role of AQP1 against the induced apoptosis.
Aggeli IK, Kapogiannatou A, Paraskevopoulou F, Gaitanaki C. | 07/3/2021 |
| AQP1 modulates tendon stem/progenitor cells senescence during tendon aging. | AQP1 modulates tendon stem/progenitor cells senescence during tendon aging.
Chen M, Li Y, Xiao L, Dai G, Lu P, Wang Y, Rui Y., Free PMC Article | 04/17/2021 |
| Aldosterone Contributed to Pulmonary Arterial Hypertension Development via Stimulating Aquaporin Expression and Pulmonary Arterial Smooth Muscle Cells Proliferation. | Aldosterone Contributed to Pulmonary Arterial Hypertension Development via Stimulating Aquaporin Expression and Pulmonary Arterial Smooth Muscle Cells Proliferation.
Wang Y, Zhong B, Wu Q, Zhu T, Wang Y, Zhang M. | 02/6/2021 |
| Effect of cGMP-activated aquaporin 1 on TRPV4 in rats with allodynia induced by chronic compression of the dorsal root ganglion. | Effect of cGMP-activated aquaporin 1 on TRPV4 in rats with allodynia induced by chronic compression of the dorsal root ganglion.
Wei H, Gao WS, Qi L, Jia L, Qu YJ, Yue SW, Zhang Y. | 12/19/2020 |
| Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization. | Aquaporin 1 alleviates acute kidney injury via PI3K-mediated macrophage M2 polarization.
Liu C, Li B, Tang K, Dong X, Xue L, Su G, Jin Y. | 12/5/2020 |
| We demonstrated that AQP1 plays a protective role in modulating acute renal injury. | Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury.
Li B, Liu C, Tang K, Dong X, Xue L, Su G, Zhang W, Jin Y., Free PMC Article | 04/4/2020 |
| AQP1 and AQP4 are remarkably correlated with the severity of hydrocephalus induced by subarachnoid hemorrhage. | The dynamic expression of aquaporins 1 and 4 in rats with hydrocephalus induced by subarachnoid haemorrhage.
Long CY, Huang GQ, Du Q, Zhou LQ, Zhou JH. | 02/22/2020 |
| Study demonstrated for the first time that AQP1 and AQP4 were involved in the cerebral edema caused by acute CO exposure in rat models, and p38 MAPK inhibitor, SB203580 effectively reduced cerebral edema and alleviated associated AQP1 and AQP4 up-regulation, suggesting the manipulation of AQP1 and AQP4 could be another "downstream-targeting" treatment of acute CO poisoning. | Involvement of p38 mitogen-activated protein kinase in altered expressions of AQP1 and AQP4 after carbon monoxide poisoning in rat astrocytes.
Li J, Jia M, Chen G, Nie S, Zheng C, Zeng W, Xu Y, Wang C, Cao X, Liu Q. | 02/15/2020 |
| the present study revealed a novel mechanism for the regulation of cardiomyocyte edema by PEDF involving lactate levels and the expression of AQP1 during oxygenglucose deprivation/recovery. | PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1.
Huang B, Miao H, Yuan Y, Qiu F, Liu X, Liu Z, Zhang H, Zhao Q, Wang M, Dong H, Zhang Z., Free PMC Article | 08/3/2019 |
| Urinary exosomal release of AQP1 and AQP2 is reduced in ischemia-reperfusion acute kidney injury. | Characterization of urinary exosomal release of aquaporin-1 and -2 after renal ischemia-reperfusion in rats.
Asvapromtada S, Sonoda H, Kinouchi M, Oshikawa S, Takahashi S, Hoshino Y, Sinlapadeelerdkul T, Yokota-Ikeda N, Matsuzaki T, Ikeda M. | 04/27/2019 |
| the decrease in AQP1 protein levels in the endothelium and AQP5 in gland ductal cells of irradiated animals may have hindered the removal of water from the lumen of ductal cells, inducing a delay in water absorption and triggering a slight lumen increase. | Effect of low radiation dose on the expression and location of aquaporins in rat submandibular gland.
Araujo MVT, Spadella MA, Chies AB, Arruda GV, Santos TM, Cavariani MM, Domeniconi RF. | 11/3/2018 |
| hydrogenrich solution was demonstrated to attenuate cardiopulmonary bypassinduced myocardial injury, suppress AQP1 and AQP4 expression following CPB treatment and protect myocardial cells via the PI3K/Akt signaling pathway. | Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
Song D, Liu X, Diao Y, Sun Y, Gao G, Zhang T, Chen K, Pei L., Free PMC Article | 10/20/2018 |
| AZ as an AQP1 inhibitor has a powerful therapeutic effect on rat AIA via inhibiting NF-kappaB activation, suggesting AQP1 inhibition might be of potential clinical interest in RA treatment. | Therapeutic effect of acetazolamide, an aquaporin 1 inhibitor, on adjuvant-induced arthritis in rats by inhibiting NF-κB signal pathway.
Cai L, Chen WN, Li R, Hu CM, Lei C, Li CM. | 09/1/2018 |
| both AQP1 mRNA and protein levels were increased in the choroid plexus of the obese rats compared to lean rats | Choroid plexus aquaporin 1 and intracranial pressure are increased in obese rats: towards an idiopathic intracranial hypertension model?
Uldall M, Bhatt DK, Kruuse C, Juhler M, Jansen-Olesen I, Jensen RH. | 05/5/2018 |
| liquid water metabolic abnormalities and intestine permeability might be the mechanism of IBS by regulating AQP1, AQP3 and AQP8 via NF-kappaB pathway. | Aquaporins 1, 3 and 8 expression in irritable bowel syndrome rats' colon via NF-κB pathway.
Chao G, Zhang S., Free PMC Article | 04/28/2018 |
| The expression of AQP1 and AQP5 was determined by Western immunoblotting. | Expression of aquaporins 1 and 5 in a model of ventilator-induced lung injury and its relation to tidal volume.
Fabregat G, García-de-la-Asunción J, Sarriá B, Mata M, Cortijo J, de Andrés J, Gallego L, Belda FJ. | 12/30/2017 |
| that elevated AQP1 levels upregulate beta-catenin protein levels, via a mechanism requiring the AQP1 COOH-terminal tail, enhancing expression of beta-catenin targets | Aquaporin 1-mediated changes in pulmonary arterial smooth muscle cell migration and proliferation involve β-catenin.
Yun X, Jiang H, Lai N, Wang J, Shimoda LA., Free PMC Article | 12/9/2017 |
| The aortic endothelia of two high-renin hypertensive rat models express greater than two times the aquaporin-1 and, at low pressures, have greater than two times the endothelial hydraulic conductivity of normotensive rats. | Chronic hypertension increases aortic endothelial hydraulic conductivity by upregulating endothelial aquaporin-1 expression.
Toussaint J, Raval CB, Nguyen T, Fadaifard H, Joshi S, Wolberg G, Quarfordt S, Jan KM, Rumschitzki DS., Free PMC Article | 11/18/2017 |
| Lipopolysaccharide significantly impaired lung function and downregulated the expression of AQP1 and AQP5 in the rat lung, all of which were attenuated by hydrogen-rich saline treatment. | Effects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs.
Tao B, Liu L, Wang N, Wang W, Jiang J, Zhang J. | 06/24/2017 |
| Aquaporin-1 upregulation/aquaporin-4 downregulation induced under subtoxic 3-nitropropionic acid treatment may play a pivotal role in water homeostasis and cell viability in the striatum. | Increased neuronal and astroglial aquaporin-1 immunoreactivity in rat striatum by chemical preconditioning with 3-nitropropionic acid.
Hoshi A, Tsunoda A, Yamamoto T, Tada M, Kakita A, Ugawa Y. | 06/24/2017 |
| the findings of our study, suggest that AQP1 promotes caspase3 activation and thereby contributes to chondrocyte apoptosis and to the development of osteoarthritis. | Aquaporin 1 contributes to chondrocyte apoptosis in a rat model of osteoarthritis.
Gao H, Gui J, Wang L, Xu Y, Jiang Y, Xiong M, Cui Y., Free PMC Article | 03/18/2017 |