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    Esr2 estrogen receptor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25149, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ERbeta Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles.

    ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles.
    Chakravarthi VP, Dilower I, Ghosh S, Borosha S, Mohamadi R, Dahiya V, Vo K, Lee EB, Ratri A, Kumar V, Marsh CA, Fields PE, Rumi MAK., Free PMC Article

    04/23/2024
    Sex and interspecies differences in ESR2-expressing cell distributions in mouse and rat brains.

    Sex and interspecies differences in ESR2-expressing cell distributions in mouse and rat brains.
    Morishita M, Higo S, Iwata K, Ishii H., Free PMC Article

    01/3/2024
    Impact of pubertal onset on region-specific Esr2 expression.

    Impact of pubertal onset on region-specific Esr2 expression.
    Drzewiecki CM, Sellinger EP, Juraska JM., Free PMC Article

    01/29/2022
    Sex-specific effects of 17beta-estradiol and dihydrotestosterone (DHT) on growth plate chondrocytes are dependent on both ERalpha and ERbeta and require palmitoylation to translocate the receptors to the plasma membrane.

    Sex-specific effects of 17β-estradiol and dihydrotestosterone (DHT) on growth plate chondrocytes are dependent on both ERα and ERβ and require palmitoylation to translocate the receptors to the plasma membrane.
    Joshua Cohen D, ElBaradie K, Boyan BD, Schwartz Z.

    01/8/2022
    Effects of dietary active soybean trypsin inhibitors on pancreatic weights, histology and expression of STAT3 and receptors for androgen and estrogen in different tissues of rats.

    Effects of dietary active soybean trypsin inhibitors on pancreatic weights, histology and expression of STAT3 and receptors for androgen and estrogen in different tissues of rats.
    Xiao CW, Wood C, Cunningham LA, Lalande M, Riding M.

    01/1/2022
    Absolute Quantification of Phosphorylated ERbeta Amino Acids in the Hippocampus of Women and in A Rat Model of Menopause.

    Absolute Quantification of Phosphorylated ERβ Amino Acids in the Hippocampus of Women and in A Rat Model of Menopause.
    Zhang M, Flury S, Kim CK, Chung WCJ, Kirk JA, Pak TR., Free PMC Article

    11/27/2021
    ERbeta regulated ovarian kisspeptin plays an important role in oocyte maturation.

    ERβ regulated ovarian kisspeptin plays an important role in oocyte maturation.
    Chakravarthi VP, Ghosh S, Housami SM, Wang H, Roby KF, Wolfe MW, Kinsey WH, Rumi MAK., Free PMC Article

    11/27/2021
    ERbeta Regulation of Gonadotropin Responses during Folliculogenesis.

    ERβ Regulation of Gonadotropin Responses during Folliculogenesis.
    Lee EB, Chakravarthi VP, Wolfe MW, Rumi MAK., Free PMC Article

    10/30/2021
    Optimization of immunohistochemical detection of rat ESR2 proteins with well-validated monoclonal antibody PPZ0506.

    Optimization of immunohistochemical detection of rat ESR2 proteins with well-validated monoclonal antibody PPZ0506.
    Hattori Y, Ishii H, Higo S, Otsuka M, Kanaya M, Matsumoto K, Ozawa M, Ozawa H.

    08/28/2021
    Sex-specific estrogen regulation of hypothalamic astrocyte estrogen receptor expression and glycogen metabolism in rats.

    Sex-specific estrogen regulation of hypothalamic astrocyte estrogen receptor expression and glycogen metabolism in rats.
    Ibrahim MMH, Bheemanapally K, Sylvester PW, Briski KP., Free PMC Article

    01/9/2021
    ER-depletion lowering the 'hypothalamus-uterus-kidney' axis functions by perturbing the renal ERbeta/Ptgds signalling pathway.

    ER-depletion lowering the 'hypothalamus-uterus-kidney' axis functions by perturbing the renal ERβ/Ptgds signalling pathway.
    Liu YR, Tang ZS, Duan JA, Chen L, Sun J, Zhou R, Song ZX, Shi XB, Zhu HY., Free PMC Article

    10/3/2020
    Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats.

    Estrogen receptor beta and G protein-coupled estrogen receptor 1 are involved in the acute estrogenic regulation of arginine-vasopressin immunoreactive levels in the supraoptic and paraventricular hypothalamic nuclei of female rats.
    Lagunas N, Marraudino M, de Amorim M, Pinos H, Collado P, Panzica G, Garcia-Segura LM, Grassi D.

    09/12/2020
    results of the present study suggest that estrogen receptor beta mediates the effects of oestradiol on vasopressin secretion in response to water deprivation

    Oestradiol acts through its beta receptor to increase vasopressin neuronal activation and secretion induced by dehydration.
    Vilhena-Franco T, Mecawi AS, Almeida-Pereira G, Lucio-Oliveira F, Elias LLK, Antunes-Rodrigues J.

    07/25/2020
    The detailed neurochemical characteristics of ERbeta-expressing neurons identified in the current study can be very essential to understand the estrogen signaling via ERbeta.

    Neurochemical Characterization of Neurons Expressing Estrogen Receptor β in the Hypothalamic Nuclei of Rats Using in Situ Hybridization and Immunofluorescence.
    Kanaya M, Higo S, Ozawa H., Free PMC Article

    05/9/2020
    activation of estrogen receptors on the morning of diestrus-2 and proestrus day asymmetrically regulates ovulation.

    Estrogen Receptors Alpha and Beta in POA-AHA Region Regulate Asymmetrically Ovulation.
    Arrieta-Cruz I, Librado-Osorio R, Flores A, Mendoza-Garcés L, Chavira R, Cárdenas M, Gutiérrez-Juárez R, Domínguez R, Cruz ME.

    01/25/2020
    ly, this study demonstrated that SSDmediated fear memory improvement in OVX rats may be attributed not to E2 levels or ERbeta activity, but to ERalpha activation in the hippocampus.

    Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
    Liu L, Yan J, Ge F, Xu X, Lu J, Shi H, Li S, Zhao Y, Zhang C.

    11/30/2019
    Deletion of the insulin promoter region revealed that nucleotide positions - 238 to - 144 (relative to the transcriptional start site) were needed for ER repression of the rat insulin II gene.

    Repression of insulin gene transcription by indirect genomic signaling via the estrogen receptor in pancreatic beta cells.
    Sekido T, Nishio SI, Ohkubo Y, Sekido K, Kitahara J, Miyamoto T, Komatsu M., Free PMC Article

    07/20/2019
    ESR2 regulates key genes in granulosa cells that are essential for follicle maturation and ovulation in the rat.

    ESR2 regulates granulosa cell genes essential for follicle maturation and ovulation.
    Khristi V, Chakravarthi VP, Singh P, Ghosh S, Pramanik A, Ratri A, Borosha S, Roby KF, Wolfe MW, Rumi MAK.

    05/11/2019
    Gonadotropin-stimulated Kiss1 expression in granulosa cells is dependent on both the activation of ESR2 and the upregulation of AP-1.

    ESR2 Is Essential for Gonadotropin-Induced Kiss1 Expression in Granulosa Cells.
    Chakravarthi VP, Khristi V, Ghosh S, Yerrathota S, Dai E, Roby KF, Wolfe MW, Rumi MAK., Free PMC Article

    04/20/2019
    hypoxia, via HIF-1alpha, increases ERbeta expression and the E2-ERbeta axis targets PHD2, HIF-1alpha, and HIF-2alpha to attenuate hypoxia-induced pulmonary hypertension development.

    Hypoxia Upregulates Estrogen Receptor β in Pulmonary Artery Endothelial Cells in a HIF-1α-Dependent Manner.
    Frump AL, Selej M, Wood JA, Albrecht M, Yakubov B, Petrache I, Lahm T., Free PMC Article

    04/20/2019
    Results showed that ER-beta expression and the number of apoptotic cells were higher and associated with disease severity in rats with tendinopathy. Mechanical stress altered the morphology of primary tenocytes and collagen fiber alignment in tendons, and up-regulated the expression of matrix metalloproteinase-9, ER-beta, and interleukin-1beta, as well as induced apoptosis in tenocytes and tendon tissue.

    Estrogen and mechanical loading-related regulation of estrogen receptor-β and apoptosis in tendinopathy.
    Hsieh JL, Jou IM, Wu CL, Wu PT, Shiau AL, Chong HE, Lo YT, Shen PC, Chen SY., Free PMC Article

    03/30/2019
    Angiotensin II stimulation of transforming growth factor beta expression in the myocytes activated p38alpha kinase via TAK1 kinase, inhibiting KLF15 expression.

    Estrogen receptor beta maintains expression of KLF15 to prevent cardiac myocyte hypertrophy in female rodents.
    Hoa N, Ge L, Korach KS, Levin ER., Free PMC Article

    03/23/2019
    bone marrow stromal cells from the OVX rats displayed increased senescence and weaker SATB2 expression, stemness, and osteogenic differentiation, while estrogen could rescue these phenotypes. Inhibition of ERb or ERa confirmed that SATB2 was associated with ERb in estrogen-mediated pluripotency and senescence of BMSCs.

    Estrogen regulates stemness and senescence of bone marrow stromal cells to prevent osteoporosis via ERβ-SATB2 pathway.
    Wu G, Xu R, Zhang P, Xiao T, Fu Y, Zhang Y, Du Y, Ye J, Cheng J, Jiang H.

    02/23/2019
    inducible nitric oxide synthase and estrogen receptor ESR2 are involved in the vascular dysfunction in female rats with type 1 diabetes

    Involvement of inducible nitric oxide synthase and estrogen receptor ESR2 (ERβ) in the vascular dysfunction in female type 1 diabetic rats.
    Sartoretto SM, Santos FF, Costa BP, Ceravolo GS, Santos-Eichler R, Carvalho MHC, Fortes ZB, Akamine EH.

    01/12/2019
    Effects of acupuncture on the levels of serum estradiol and pituitary estrogen receptor beta in a rat model of induced super ovulation.

    Effects of acupuncture on the levels of serum estradiol and pituitary estrogen receptor beta in a rat model of induced super ovulation.
    Fu H, Sun J, Tan Y, Zhou H, Xu W, Zhou J, Chen D, Zhang C, Zhu X, Zhang Y, Wu X, Xi Z.

    03/3/2018
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