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    ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Homo sapiens (human) ]

    Gene ID: 25, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    VNTR polymorphism in the breakpoint region of ABL1 and susceptibility to bladder cancer.

    VNTR polymorphism in the breakpoint region of ABL1 and susceptibility to bladder cancer.
    Kim MH, Yang GE, Jeong MS, Mun JY, Lee SY, Nam JK, Choi YH, Kim TN, Leem SH., Free PMC Article

    08/27/2024
    Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort.

    Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort.
    Chaudhary P, Chaudhary S, Patel F, Patel S, Vaishnani T, Trivedi N, Patel D, Sonagara T, Hirapara A, Vyas K, Patel L, Kumar R, Chakraborty N, Sharma D, Suthar J, Kamdar P, Jajodia E, Ahmad F, Arora N., Free PMC Article

    08/2/2024
    Human ABL1 deficiency syndrome (HADS) is a recognizable syndrome distinct from ABL1-related congenital heart defects and skeletal malformations syndrome.

    Human ABL1 deficiency syndrome (HADS) is a recognizable syndrome distinct from ABL1-related congenital heart defects and skeletal malformations syndrome.
    AlAbdi L, Neuhann T, Prott EC, Schön U, Abdulwahab F, Faqeih E, Alkuraya FS.

    07/8/2024
    Characteristics and literature review of ETV6::ABL1 fusion gene-positive acute myeloid leukemia.

    Characteristics and literature review of ETV6::ABL1 fusion gene-positive acute myeloid leukemia.
    Xue S, Sun HP, Huang XB, Chen X, Wang T, Ma W, Tian Y, Pan ZL, Li LH, Zhang L, Liu HX, Cao XY.

    07/5/2024
    Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL.

    Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL.
    Bastian L, Beder T, Barz MJ, Bendig S, Bartsch L, Walter W, Wolgast N, Brändl B, Rohrandt C, Hansen BT, Hartmann AM, Iben K, Das Gupta D, Denker M, Zimmermann J, Wittig M, Chitadze G, Neumann M, Schneller F, Fiedler W, Steffen B, Stelljes M, Faul C, Schwartz S, Müller FJ, Cario G, Harder L, Haferlach C, Pfeifer H, Gökbuget N, Brüggemann M, Baldus CD., Free PMC Article

    04/8/2024
    Zinc as a potential regulator of the BCR-ABL oncogene in chronic myelocytic leukemia cells.

    Zinc as a potential regulator of the BCR-ABL oncogene in chronic myelocytic leukemia cells.
    Zhu B, Sun L, Li Z, Shang P, Yang C, Li K, Li J, Zhi Q, Hua Z.

    03/18/2024
    A case report of a truncated ABL1 mutation in 2 cases with Philadelphia chromosome-positive B cell precursor acute lymphoblastic leukemia.

    A case report of a truncated ABL1 mutation in 2 cases with Philadelphia chromosome-positive B cell precursor acute lymphoblastic leukemia.
    Kato K, Takagi S, Takano H, Tsunoda S, Watanabe O, Yamaguchi K, Kageyama K, Kaji D, Taya Y, Nishida A, Ishiwata K, Yamamoto H, Yamamoto G, Asano-Mori Y, Koike Y, Makino S, Wake A, Taniguchi S, Uchida N.

    02/8/2024
    Spectrum of BCR-ABL mutations in Azerbaijanian imatinib-resistant patients with chronic myeloid leukemia.

    Spectrum of BCR-ABL mutations in Azerbaijanian imatinib-resistant patients with chronic myeloid leukemia.
    Hasanova A, Asadov C, Karimova N, Shirinova A, Aliyeva G, Alimirzoyeva Z., Free PMC Article

    01/12/2024
    Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.

    Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.
    Motaln H, Čerček U, Yamoah A, Tripathi P, Aronica E, Goswami A, Rogelj B., Free PMC Article

    10/10/2023
    Histone demethylase PHF8 facilitates the development of chronic myeloid leukaemia by directly targeting BCR::ABL1.

    Histone demethylase PHF8 facilitates the development of chronic myeloid leukaemia by directly targeting BCR::ABL1.
    Feng H, Fu Y, Cui Z, Zhou M, Zhang L, Gao Z, Ma S, Chen C.

    09/15/2023
    The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia.

    The interplay between telomeric complex members and BCR::ABL1 oncogenic tyrosine kinase in the maintenance of telomere length in chronic myeloid leukemia.
    Deręgowska A, Pępek M, Solarska I, Machnicki MM, Pruszczyk K, Dudziński M, Niesiobędzka-Krężel J, Seferyńska I, Sawicki W, Wnuk M, Stokłosa T., Free PMC Article

    08/3/2023
    Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.

    Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.
    Hefni E, Menon D, Ma T, Asiedu EB, Sultan A, Meiller T, Schneider A, Sodhi A, Montaner S., Free PMC Article

    06/15/2023
    Extramedullary T-lymphoblastic blast crisis in chronic myeloid leukemia: A very rare case associated with comutation of ABL1 T315I and H396R.

    Extramedullary T-lymphoblastic blast crisis in chronic myeloid leukemia: A very rare case associated with comutation of ABL1 T315I and H396R.
    Zhang Y, Li T, Li X, Zheng T, Xi Y, Wang K, Wang H.

    03/23/2023
    Emergence of a BCR::ABL1 rearrangement following a uniquely complex clonal evolution pattern in a patient undergoing Fms-like tyrosine kinase 3 inhibitor therapy for acute myeloid leukemia.

    Emergence of a BCR::ABL1 rearrangement following a uniquely complex clonal evolution pattern in a patient undergoing Fms-like tyrosine kinase 3 inhibitor therapy for acute myeloid leukemia.
    Park B, Kim J, Kim M, Cho YU, Hwang SH, Jang S, Seo EJ, Choi EJ, Park CJ.

    03/22/2023
    BH3 mimetics and TKI combined therapy for Chronic Myeloid Leukemia.

    BH3 mimetics and TKI combined therapy for Chronic Myeloid Leukemia.
    Brumatti G, Kaloni D, Castro FA, Amarante-Mendes GP.

    02/11/2023
    c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation.

    c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation.
    Lee S, Ryu HG, Kweon SH, Kim H, Park H, Lee KH, Jang SM, Na CH, Kim S, Ko HS., Free PMC Article

    01/14/2023
    Deep sequencing reveals the spectrum of BCR-ABL1 mutations upon front-line therapy resistance in chronic myeloid leukemia: An Eastern-Indian cohort study.

    Deep sequencing reveals the spectrum of BCR-ABL1 mutations upon front-line therapy resistance in chronic myeloid leukemia: An Eastern-Indian cohort study.
    Dey S, Basu S, Shah S, Bhattacharyya D, Gupta PP, Acharjee M, Roychoudhury S, Nath S.

    01/11/2023
    Mutation Profile in BCR-ABL1-Negative Myeloproliferative Neoplasms: A Single-Center Experience From India.

    Mutation Profile in BCR-ABL1-Negative Myeloproliferative Neoplasms: A Single-Center Experience From India.
    Maddali M, Kulkarni UP, Ravindra N, Arunachalam AK, Venkatraman A, Lionel S, Manipadam MT, Devasia AJ, Korula A, Fouzia NA, Abraham A, Srivastava A, George B, Balasubramanian P, Mathews V., Free PMC Article

    12/3/2022
    Roles for c-Abl in postoperative neurodegeneration.

    Roles for c-Abl in postoperative neurodegeneration.
    Feng L, Fu S, Yao Y, Li Y, Xu L, Zhao Y, Luo L., Free PMC Article

    11/5/2022
    Hsa_circ_0088196 suppresses trophoblast migration and invasion by the miR-525-5p/ABL1 axis and the PI3K/AKT signaling pathway.

    Hsa_circ_0088196 suppresses trophoblast migration and invasion by the miR-525-5p/ABL1 axis and the PI3K/AKT signaling pathway.
    Shi F, Li L.

    10/22/2022
    The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination.

    The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination.
    Xu F, Yao W, Xue Y, Sun Q, Cao C.

    09/24/2022
    Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes.

    Molecular profile reveals immune-associated markers of medulloblastoma for different subtypes.
    Chen J, Kang Z, Li S, Wang C, Zheng X, Cai Z, Pan L, Chen F, Li W., Free PMC Article

    09/3/2022
    Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells.

    Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells.
    Le Vely B, Phan C, Berrebeh N, Thuillet R, Ottaviani M, Chelgham MK, Chaumais MC, Amazit L, Humbert M, Huertas A, Guignabert C, Tu L.

    08/20/2022
    miR-203a-3p, ABL1 and TP63 gene expression is altered in the endometrium of women with endometriosis.

    miR-203a-3p, ABL1 and TP63 gene expression is altered in the endometrium of women with endometriosis.
    Pashaei M, Mashayekhi F, Zahiri Z, Salehi Z.

    07/9/2022
    Protein tyrosine kinase Abl promotes hepatitis C virus particle assembly via interaction with viral substrate activator NS5A.

    Protein tyrosine kinase Abl promotes hepatitis C virus particle assembly via interaction with viral substrate activator NS5A.
    Miyamoto D, Takeuchi K, Chihara K, Fujieda S, Sada K., Free PMC Article

    05/14/2022
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