| Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells. | Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells.
Park JM, Su YH, Fan CS, Chen HH, Qiu YK, Chen LL, Chen HA, Ramasamy TS, Chang JS, Huang SY, Chang WW, Lee AY, Huang TS, Kuo CC, Chiu CF., Free PMC Article | 10/9/2024 |
| METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer. | METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer.
Li L, Zeng J, He S, Yang Y, Wang C., Free PMC Article | 06/27/2024 |
| Ferritin heavy chain supports stability and function of the regulatory T cell lineage. | Ferritin heavy chain supports stability and function of the regulatory T cell lineage.
Wu Q, Carlos AR, Braza F, Bergman ML, Kitoko JZ, Bastos-Amador P, Cuadrado E, Martins R, Oliveira BS, Martins VC, Scicluna BP, Landry JJ, Jung FE, Ademolue TW, Peitzsch M, Almeida-Santos J, Thompson J, Cardoso S, Ventura P, Slot M, Rontogianni S, Ribeiro V, Domingues VDS, Cabral IA, Weis S, Groth M, Ameneiro C, Fidalgo M, Wang F, Demengeot J, Amsen D, Soares MP., Free PMC Article | 04/24/2024 |
| FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation. | FTH1 protects against osteoarthritis by MAPK pathway inhibition of extracellular matrix degradation.
Yuan Z, Yang L, Li Y, Li X, Peng C, Pan J, Cai D., Free PMC Article | 04/17/2024 |
| M[7]G modification of FTH1 and pri-miR-26a regulates ferroptosis and chemotherapy resistance in osteosarcoma. | M(7)G modification of FTH1 and pri-miR-26a regulates ferroptosis and chemotherapy resistance in osteosarcoma.
He M, Wang Y, Xie J, Pu J, Shen Z, Wang A, Li T, Wang T, Li G, Liu Y, Mei Z, Ren Z, Wang W, Liu X, Hong J, Liu Q, Lei H, He X, Du W, Yuan Y, Yang L. | 01/31/2024 |
| Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.H137Lfs*4). | Distribution of ferritin complex in the adult brain and altered composition in neuroferritinopathy due to a novel variant in the ferritin heavy chain gene FTH1 (c.409_410del; p.H137Lfs*4).
Umathum V, Weber A, Amsel D, Alexopoulos I, Becker C, Roth A, Günther A, Selignow C, Ritschel N, Nishimura A, Schaiter A, Németh A, van der Ven PFM, Acker T, Schänzer A., Free PMC Article | 12/20/2023 |
| FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma. | FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma.
Liao Q, Yang J, Lu Z, Jiang Q, Gong Y, Liu L, Peng H, Wang Q, Zhang X, Liu Z., Free PMC Article | 12/4/2023 |
| AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer. | AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer.
Shi Z, Yuan H, Cao L, Lin Y. | 10/5/2023 |
| NSUN5-FTH1 Axis Inhibits Ferroptosis to Promote the Growth of Gastric Cancer Cells. | NSUN5-FTH1 Axis Inhibits Ferroptosis to Promote the Growth of Gastric Cancer Cells.
Su Y, Liu J, Zheng Z, Shi L, Huang W, Huang X, Ye C, Qi J, Wang W, Zhuang H. | 09/14/2023 |
| LncRNA CACNA1G-AS1 up-regulates FTH1 to inhibit ferroptosis and promote malignant phenotypes in ovarian cancer cells. | LncRNA CACNA1G-AS1 up-regulates FTH1 to inhibit ferroptosis and promote malignant phenotypes in ovarian cancer cells.
Jin Y, Qiu J, Lu X, Ma Y, Li G., Free PMC Article | 06/21/2023 |
| RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability. | RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J. | 06/1/2023 |
| WDR45 mutation dysregulates iron homeostasis by promoting the chaperone-mediated autophagic degradation of ferritin heavy chain in an ER stress/p38 dependent mechanism. | WDR45 mutation dysregulates iron homeostasis by promoting the chaperone-mediated autophagic degradation of ferritin heavy chain in an ER stress/p38 dependent mechanism.
Xiong Q, Sun H, Xing W, Li X, Chen G, Zhao Z, Wu C, Li P. | 05/31/2023 |
| Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration. | Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration.
Di Sanzo M, Cozzolino F, Battaglia AM, Aversa I, Monaco V, Sacco A, Biamonte F, Palmieri C, Procopio F, Santamaria G, Ortuso F, Pucci P, Monti M, Faniello MC., Free PMC Article | 11/19/2022 |
| SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients. | SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients.
Muhammad JS, ElGhazali G, Shafarin J, Mohammad MG, Abu-Qiyas A, Hamad M., Free PMC Article | 10/22/2022 |
| TNFalpha-induced abnormal activation of TNFR/NF-kappaB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion. | TNFα-induced abnormal activation of TNFR/NF-κB/FTH1 in endometrium is involved in the pathogenesis of early spontaneous abortion.
Wen Y, Cheng M, Qin L, Xu W., Free PMC Article | 05/21/2022 |
| Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases. | Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain: Implication for Protein Aggregation in Down Syndrome Dementia, Alzheimer's, and Parkinson's Diseases.
Raha AA, Biswas A, Henderson J, Chakraborty S, Holland A, Friedland RP, Mukaetova-Ladinska E, Zaman S, Raha-Chowdhury R., Free PMC Article | 04/16/2022 |
| Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c-MYC. | Ferritin heavy chain (FTH1) exerts significant antigrowth effects in breast cancer cells by inhibiting the expression of c-MYC.
Ali A, Shafarin J, Abu Jabal R, Aljabi N, Hamad M, Sualeh Muhammad J, Unnikannan H, Hamad M., Free PMC Article | 03/26/2022 |
| Higher CSF Ferritin Heavy-Chain (Fth1) and Transferrin Predict Better Neurocognitive Performance in People with HIV. | Higher CSF Ferritin Heavy-Chain (Fth1) and Transferrin Predict Better Neurocognitive Performance in People with HIV.
Kaur H, Bush WS, Letendre SL, Ellis RJ, Heaton RK, Patton SM, Connor JR, Samuels DC, Franklin DR, Hulgan T, Kallianpur AR., Free PMC Article | 02/5/2022 |
| Hemin enhances radiosensitivity of lung cancer cells through ferroptosis. | Hemin enhances radiosensitivity of lung cancer cells through ferroptosis.
Almahi WA, Yu KN, Mohammed F, Kong P, Han W. | 01/15/2022 |
| Characterization of cells expressing MRI reporters for the analysis of epigenetics. | Characterization of cells expressing MRI reporters for the analysis of epigenetics.
Sugaya K. | 01/1/2022 |
| CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles. | CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles.
Yanatori I, Richardson DR, Dhekne HS, Toyokuni S, Kishi F., Free PMC Article | 12/11/2021 |
| Increasing ferritin predicts early death in adult hemophagocytic lymphohistiocytosis. | Increasing ferritin predicts early death in adult hemophagocytic lymphohistiocytosis.
Abou Shaar R, Eby CS, van Dorp S, de Witte T, Otrock ZK. | 12/4/2021 |
| Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance. | Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance.
Tirinato L, Marafioti MG, Pagliari F, Jansen J, Aversa I, Hanley R, Nisticò C, Garcia-Calderón D, Genard G, Guerreiro JF, Costanzo FS, Seco J., Free PMC Article | 11/27/2021 |
| Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells. | Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells.
Otsu W, Ishida K, Chinen N, Nakamura S, Shimazawa M, Tsusaki H, Hara H., Free PMC Article | 11/22/2021 |
| Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity. | Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity.
Zhang J, Cao J, Xu H, Dong G, Huang K, Wu W, Ye J, Fu J., Free PMC Article | 10/30/2021 |