| propose that eyeblink conditioning (EBC)-induced secretin release from Purkinje cells modulates EBC acquisition by reducing surface expression of Kv1.2 at one or both of these sites | Cerebellar secretin modulates eyeblink classical conditioning.
Fuchs JR, Robinson GM, Dean AM, Schoenberg HE, Williams MR, Morielli AD, Green JT., Free PMC Article | 07/25/2015 |
| Secretin decreases cell surface Kv1.2 alpha-subunit levels by modulating Kv1.2 alpha- subunit endocytic trafficking. | Cellular mechanisms and behavioral consequences of Kv1.2 regulation in the rat cerebellum.
Williams MR, Fuchs JR, Green JT, Morielli AD., Free PMC Article | 09/22/2012 |
| Ursodeoxycholic acid is conjugated in order to promote secretin-stimulated hydrocholeresis in rats through Ae2, microtubules, intracellular Ca(2+), PKCalpha, PI3K, PKA, and MEK. | Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.
Úriz M, Sáez E, Prieto J, Medina JF, Banales JM., Free PMC Article | 09/1/2012 |
| Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore. | Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.
Dong M, Lam PC, Pinon DI, Hosohata K, Orry A, Sexton PM, Abagyan R, Miller LJ., Free PMC Article | 09/10/2011 |
| Data show that in secretin/secretin receptor binding, the alpha-helix in natural secretin was oriented approximately parallel to the amino-terminal alpha-helix of the receptor. | Importance of each residue within secretin for receptor binding and biological activity.
Dong M, Le A, Te JA, Pinon DI, Bordner AJ, Miller LJ., Free PMC Article | 08/6/2011 |
| propose that secretin works at multiple levels in the hypothalamus, pituitary, and kidney to regulate water homeostasis | Secretin as a neurohypophysial factor regulating body water homeostasis.
Chu JY, Lee LT, Lai CH, Vaudry H, Chan YS, Yung WH, Chow BK., Free PMC Article | 01/21/2010 |
| provide evidence of the endogenous release of secretin in the hypothalamus and the mechanisms underlying this release | Endogenous release of secretin from the hypothalamus.
Chu JY, Yung WH, Chow BK. | 01/21/2010 |
| Atrial natriuretic factor may play a protective role by reducing secretin response to avoid overstimulation. | Atrial natriuretic factor negatively modulates secretin intracellular signaling in the exocrine pancreas.
Sabbatini ME, Vatta MS, Davio CA, Bianciotti LG. | 01/21/2010 |
| Secretin mRNA is present in gastric mucosa and the locally released secretin may exert a paracrine effect to inhibit acid secretion. | Evidence on the presence of secretin cells in the gastric antral and oxyntic mucosa.
Chey WY, Chang CH, Pan HJ, Chang C, Kim BM, Park IS, Chang TM. | 01/21/2010 |
| Solid evidence for the role of secretin as a neuropeptide in the mammalian central nervous system. | Endogenous release and multiple actions of secretin in the rat cerebellum.
Lee SM, Chen L, Chow BK, Yung WH. | 01/21/2010 |
| solitary nucleus neurons are activated by secretin as a consequence of activation of a non-selective cation conductance and support the emerging view that secretin can act as a neuropeptide within the CNS. | Secretin depolarizes nucleus tractus solitarius neurons through activation of a nonselective cationic conductance.
Yang B, Goulet M, Boismenu R, Ferguson AV. | 01/21/2010 |
| first immunohistochemical demonstration of secretin-immunoreactive elements in the brain stem and in primary sensory ganglia | What may be the anatomical basis that secretin can improve the mental functions in autism?
Köves K, Kausz M, Reser D, Horváth K. | 01/21/2010 |
| COlitis in ganciclovir-treated Sec-simplex virus thymidine kinase mice arises from depletion of secretin gene-expressing lymphoid cells. | Sudden onset of colitis after ablation of secretin-expressing lymphocytes in transgenic mice.
Rindi G, Civallero M, Candusso ME, Marchetti A, Klersy C, Nano R, Leiter AB. | 01/21/2010 |
| role in activating chromogranin A transcription | Secretin activation of chromogranin A gene transcription. Identification of the signaling pathways in cis and in trans.
Mahapatra NR, Mahata M, O'Connor DT, Mahata SK. | 01/21/2010 |
| Review. In the rat cerebellum, secretin functions as a retrograde messenger to facilitate GABA transmission, indicating that it can modulate motor and other functions. | Secretin as a neuropeptide.
Ng SS, Yung WH, Chow BK. | 01/21/2010 |
| secretin stimulates cholehepatic shunting of conjugated bile acids and is associated with increased cholangiocyte apical membrane ASBT | Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats.
Alpini G, Glaser S, Baiocchi L, Francis H, Xia X, Lesage G. | 01/21/2010 |