| EM66 (peptide derived from SCG2) gene expression is modulated by a negative energy status and suggest interactions between EM66 and NPY to regulate food intake through the POMC system. | Effect of food deprivation on the hypothalamic gene expression of the secretogranin II-derived peptide EM66 in rat.
Trebak F, Dubuc I, Picot M, Alaoui A, Leprince J, Prévost G, Anouar Y, Magoul R, Chartrel N. | 06/9/2018 |
| Manserin localizes to secretory cells in the oviduct and may be involved in stress-induced gynecological disorders. | Localization of manserin, a secretogranin II-derived neuropeptide, in the oviduct of female rats.
Ida-Eto M, Nomura M, Ohkawara T, Narita N, Narita M. | 12/20/2014 |
| Manserin localizes to rat thyroid follicular epithelial cells and also to some parafollicular cells | Subtype-specific parafollicular localization of the neuropeptide manserin in the rat thyroid gland.
Ohkawara T, Oyabu A, Ida-Eto M, Tashiro Y, Narita N, Narita M. | 06/29/2013 |
| The secretogranin II fragment secretoneurin reduces ischemia/reperfusion injury in the isolated perfused rat heart. | Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties.
Røsjø H, Stridsberg M, Florholmen G, Stensløkken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, Øie E, Louch WE, Omland T, Christensen G., Free PMC Article | 09/29/2012 |
| results indicate that manserin, occurring in the endocrine pancreas, may have a potential role in the endocrine system | Manserin, a secretogranin II-derived peptide, distributes in the rat endocrine pancreas colocalized with islet-cell specific manner.
Tano K, Oyabu A, Tashiro Y, Kamada N, Narita N, Nasu F, Narita M. | 11/27/2010 |
| SgII is a critical factor for the regulation of DCG biogenesis in neuroendocrine cells | Pro-hormone secretogranin II regulates dense core secretory granule biogenesis in catecholaminergic cells.
Courel M, Soler-Jover A, Rodriguez-Flores JL, Mahata SK, Elias S, Montero-Hadjadje M, Anouar Y, Giuly RJ, O'Connor DT, Taupenot L., Free PMC Article | 05/3/2010 |
| analysis of the N- and C-terminal alpha-helical domains in secretogranin II | Sorting of the neuroendocrine secretory protein Secretogranin II into the regulated secretory pathway: role of N- and C-terminal alpha-helical domains.
Courel M, Vasquez MS, Hook VY, Mahata SK, Taupenot L., Free PMC Article | 01/21/2010 |
| MAPK signaling and ATF3 action are essential for full SgII promoter activation by GnRHa through a canonical CRE | 3', 5'-cyclic adenosine 5'-monophosphate response element-dependent transcriptional regulation of the secretogranin II gene promoter depends on gonadotropin-releasing hormone-induced mitogen-activated protein kinase activation and the transactivator activating transcription factor 3.
Xie J, Roberson MS., Free PMC Article | 01/21/2010 |
| A novel 40 amino acid neuropeptide designated manserin (residues 529-568 of secretogranin II) localizes to endocrine cells of the pituitary anterior lobe and is observed in neuronal cells of hypothalamic nuclei and neurons in the median eminence. | Manserin, a novel peptide from secretogranin II in the neuroendocrine system.
Yajima A, Ikeda M, Miyazaki K, Maeshima T, Narita N, Narita M. | 01/21/2010 |
| CgA and SgII (chromogranin A and secretogranin II) mRNA were expressed in both mammary adenocarcinoma and fibroadenoma tumors, but SgI (secretogranin I) mRNA was not detected in either. | Expression of chromogranin/secretogranin mRNA in spontaneous mammary tumors in aging Fischer-344 rats.
Umemura S, Iwasaka T, Osamura RY. | 01/21/2010 |
| GnRH-induced activation of the rat SgII promoter in the alphaT3-1 cell line requires cAMP-dependent protein kinase activity and a functional CRE within the 5'-flanking region of the gene | Gonadotropin-releasing hormone-induced stimulation of the rat secretogranin II promoter involves activation of CREB.
Song SB, Rhee M, Roberson MS, Maurer RA, Kim KE. | 01/21/2010 |
| PCP[phencyclidine] modulates secretogranin II[sg II] expression in prefrontal cortex tissue in the absence of afferent inputs and that the nature of these changes is dependent upon the duration of exposure to and/or withdrawal from PCP | Differential effects of phencyclidine application on secretogranin II expression in organotypic slices of rat prefrontal cortex.
Hinterhoelzl JK, Salimi K, Humpel C, Singewald N, Adlassnig C, Fischer-Colbrie R, Fleischhacker WW, Marksteiner J. | 01/21/2010 |