| Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects. | Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects.
Urata Y, Salehi R, Wyse BA, Jahangiri S, Librach CL, Tzeng CR, Osuga Y, Tsang B., Free PMC Article | 11/2/2023 |
| Adolescent binge-like alcohol exposure dysregulates NPY and CGRP in rats: Behavioural and immunochemical evidence. | Adolescent binge-like alcohol exposure dysregulates NPY and CGRP in rats: Behavioural and immunochemical evidence.
Brancato A, Castelli V, Cannizzaro C, Tringali G. | 02/16/2023 |
| Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis. | Neuropeptide Y in the amygdala contributes to neuropathic pain-like behaviors in rats via the neuropeptide Y receptor type 2/mitogen-activated protein kinase axis.
Yan W, Liu W, Wu J, Wu L, Xuan S, Wang W, Shang A., Free PMC Article | 05/7/2022 |
| Neuropeptide Y, calcitonin gene-related peptide, and neurokinin A in brain regions of HAB rats correlate with anxiety-like behaviours. | Neuropeptide Y, calcitonin gene-related peptide, and neurokinin A in brain regions of HAB rats correlate with anxiety-like behaviours.
Carboni L, El Khoury A, Beiderbeck DI, Neumann ID, Mathé AA. | 04/23/2022 |
| Sirtuins and neuropeptide y downregulation in Flinders Sensitive Line rat model of depression. | Sirtuins and neuropeptide y downregulation in Flinders Sensitive Line rat model of depression.
Stiernborg M, Efstathopoulos P, Lennartsson A, Lavebratt C, Mathé AA. | 04/9/2022 |
| Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL1betainduced extracellular matrix degradation. | Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL‑1β‑induced extracellular matrix degradation.
Sun K, Zhu J, Sun J, Sun X, Huan L, Zhang B, Lin F, Zheng B, Jiang J, Luo X, Xu X, Shi J., Free PMC Article | 02/19/2022 |
| Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus. | Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus.
Borroto-Escuela DO, Pita-Rodriguez M, Fores-Pons R, Barbancho MA, Fuxe K, Narváez M. | 10/2/2021 |
| Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner. | Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner.
Urata Y, Salehi R, Lima PDA, Osuga Y, Tsang BK., Free PMC Article | 10/24/2020 |
| Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats. | Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats.
Gumbs MCR, Vuuregge AH, Eggels L, Unmehopa UA, Lamuadni K, Mul JD, la Fleur SE., Free PMC Article | 09/19/2020 |
| Neuropeptide Y knockdown in the dorsomedial hypothalamus improved basal and obesity-induced decrease in bone mass density. | Neuropeptide Y knockdown in the dorsomedial hypothalamus improved basal and obesity-induced decrease in bone mass density.
Qin Q, Chen P, Cui Z, Wang J, Xie B, Zhang S, Mei X, Duan X, Zhang J, Wang S. | 08/29/2020 |
| The cardioprotective action of Nur77 can be ascribed to both inhibition of circulating NPY levels and to cardiomyocyte-specific modulation of NPY-NPY1R signaling to prevent cardiac remodeling. | Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis.
Medzikovic L, van Roomen C, Baartscheer A, van Loenen PB, de Vos J, Bakker ENTP, Koenis DS, Damanafshan A, Creemers EE, Arkenbout EK, de Vries CJM, de Waard V. | 11/16/2019 |
| DM modestly affects the NPY system in the retina and these effects are not prevented by sitagliptin treatment. These observations suggest that DPP-IV enzyme is not underlying the NPY changes detected in the retina induced by type 1 DM. | Impact of type 1 diabetes mellitus and sitagliptin treatment on the neuropeptide Y system of rat retina.
Campos EJ, Martins J, Brudzewsky D, Correia S, Santiago AR, Woldbye DP, Ambrósio AF. | 06/29/2019 |
| Neuropeptide Y expression was significantly less in the hippocampus of severely brain injured animals with posttraumatic epilepsy compared to animals that do not develop posttraumatic epilepsy. | Hippocampal neuropeptide Y protein expression following controlled cortical impact and posttraumatic epilepsy.
Sun Z, Liu S, Kharlamov EA, Miller ER, Kelly KM. | 04/13/2019 |
| Study found the amount of the fat mass/obesity-associated protein (FTO) protein increased in obese rats, while FTO and neuropeptide Y levels decreased in the groups treated with topiramate. The mechanism of the effect of topiramate to create a state of obesity is thought to involve the decrease in the levels of NPY and FTO. | The investigation of the effects of topiramate on the hypothalamic levels of fat mass/obesity-associated protein and neuropeptide Y in obese female rats.
Alkan I, Altunkaynak BZ, Altun G, Erener E. | 03/30/2019 |
| Neuropeptide Y may modulate excitatory and inhibitory cortical activity (as in plastic changes during learning) possibly via a global but also slow homeostatic control of glutamatergic transmission. | Neuropeptide Y as a possible homeostatic element for changes in cortical excitability induced by repetitive transcranial magnetic stimulation.
Jazmati D, Neubacher U, Funke K. | 02/23/2019 |
| NPY via the Y1 receptor plays an important role in mediating the adaptation mechanism against chronic stress. | Central Neuropeptide Y Plays an Important Role in Mediating the Adaptation Mechanism Against Chronic Stress in Male Rats.
Yang Y, Babygirija R, Zheng J, Shi B, Sun W, Zheng X, Zhang F, Cao Y. | 02/9/2019 |
| The levels of NPY and NPY1R in MSCs undergoing osteoblastic differentiation were upregulated after MLT administration. results show that MLT promotes osteoblastic differentiation of MSCs and fracture healing by NPY/NPY1R signaling. | Melatonin Induces Osteoblastic Differentiation of Mesenchymal Stem Cells and Promotes Fracture Healing in a Rat Model of Femoral Fracture via Neuropeptide Y/Neuropeptide Y Receptor Y1 Signaling.
Dong P, Gu X, Zhu G, Li M, Ma B, Zi Y. | 12/22/2018 |
| TRPA1-mediated spontaneous [Ca(2+)]i increase modulates the spontaneous release of peptide hormones from astrocytes. | Transient receptor potential ankyrin 1 channels are involved in spontaneous peptide hormone release from astrocytes.
Takizawa M, Harada K, Nakamura K, Tsuboi T. | 10/13/2018 |
| This study demonstrated that Adolescent Alcohol Exposure-Induced Changes Neuropeptide Y activity in the amygdala in adults. | Adolescent Alcohol Exposure-Induced Changes in Alpha-Melanocyte Stimulating Hormone and Neuropeptide Y Pathways via Histone Acetylation in the Brain During Adulthood.
Kokare DM, Kyzar EJ, Zhang H, Sakharkar AJ, Pandey SC., Free PMC Article | 05/19/2018 |
| NPY and Y1 were expressed by pulmonary intravascular and intraalveolar leukocytes. Y1 was up-regulated by pulmonary intravascular and intraalveolar leukocytes during allograft rejection while Y2 could not be detected. | Non-neuronal neuropeptide Y and its receptors during acute rejection of rat pulmonary allografts.
Schmitz J, Zakrzewicz A, Wilker S, Kuncová J, Hecker A, Grau V, Padberg W, Holler JPN. | 02/10/2018 |
| PG early treatment prevented Y1R upregulation and resulted in lower NPY, Y2R and GalR1 mRNA levels. In the chronic phase, injured rats showed well-established mechanical and cold allodynia and significant increases in galanin, NPY, GalR1 and Y1R mRNAs, while maintaining reduced GalR2 expression. Animals receiving PG treatment showed basal expression levels of galanin, NPY, GalR1 and Y1R, and reduced Y2R mRNA levels | Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.
Coronel MF, Villar MJ, Brumovsky PR, González SL. | 12/2/2017 |
| NPY-system works in close coordination with the melanocortin (MC) and corticotropin-releasing hormone (CRH) systems to modulate alcohol intake and body weight | Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight.
Qiu B, Bell RL, Cao Y, Zhang L, Stewart RB, Graves T, Lumeng L, Yong W, Liang T., Free PMC Article | 10/28/2017 |
| Cardiac metabolic remodeling is an early change in the myocardium before the presence of typical morphological ventricular remodeling following cardiac pressure overload, and pretreatment with trimetazidine may at least partly reverse the acute metabolic disturbance, perhaps via regulation of the NPY system. | Trimetazidine attenuates pressure overload-induced early cardiac energy dysfunction via regulation of neuropeptide Y system in a rat model of abdominal aortic constriction.
Chen A, Li W, Chen X, Shen Y, Dai W, Dong Q, Li X, Ou C, Chen M., Free PMC Article | 10/7/2017 |
| Neuropeptide Y gene expression is increased in the amygdalostriatal transition area during conditioned fear. | Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear.
Leitermann RJ, Rostkowski AB, Urban JH., Free PMC Article | 09/16/2017 |
| a key central circuit mechanism through which hypothalamic NPY signals drive these hunger responses, is elucidated. | Medullary Reticular Neurons Mediate Neuropeptide Y-Induced Metabolic Inhibition and Mastication.
Nakamura Y, Yanagawa Y, Morrison SF, Nakamura K., Free PMC Article | 07/15/2017 |