| Vasohibin-1 has alpha-tubulin detyrosinating activity in glomerular podocytes. | Vasohibin-1 has α-tubulin detyrosinating activity in glomerular podocytes.
Mifune T, Tanabe K, Nakashima Y, Tanimura S, Sugiyama H, Sato Y, Wada J. | 03/19/2022 |
| Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice. | Vasohibin-1 rescues erectile function through up-regulation of angiogenic factors in the diabetic mice.
Song KM, Kim WJ, Choi MJ, Kwon KD, Limanjaya A, Ghatak K, Ock J, Yin GN, Sato Y, Hong SS, Ryu JK, Suh JK., Free PMC Article | 08/7/2021 |
| Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia. | Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia.
Hantelys F, Godet AC, David F, Tatin F, Renaud-Gabardos E, Pujol F, Diallo LH, Ader I, Ligat L, Henras AK, Sato Y, Parini A, Lacazette E, Garmy-Susini B, Prats AC., Free PMC Article | 05/30/2020 |
| VASH1 expression could have protective effects on cisplatin-induced AKI probably by maintaining the number and function of peritubular capillaries. | Renal tubular injury exacerbated by vasohibin-1 deficiency in a murine cisplatin-induced acute kidney injury model.
Tanimura S, Tanabe K, Miyake H, Masuda K, Tsushida K, Morioka T, Sugiyama H, Sato Y, Wada J. | 03/21/2020 |
| replicative senescence, the downregulation of VASH1 expression in endothelial cells was caused, at least in part, by the alteration of microRNA expression. | Age-associated downregulation of vasohibin-1 in vascular endothelial cells.
Takeda E, Suzuki Y, Sato Y., Free PMC Article | 06/10/2017 |
| These results indicate that cancer cells proteolytically inactivate VASH1 protein secreted by ECs in the tumour microenvironment | Proteolytic inactivation of anti-angiogenic vasohibin-1 by cancer cells.
Saito M, Suzuki Y, Yano S, Miyazaki T, Sato Y. | 02/4/2017 |
| Unaffected fibrosis and angiogenesis seen by knocking out endogenous vasohibin-1. | Hepatic fibrosis and angiogenesis after bile duct ligation are endogenously expressed vasohibin-1 independent.
Furutani Y, Shiozaki-Sato Y, Hara M, Sato Y, Kojima S. | 09/12/2015 |
| endogenous VASH1 may regulate the development of diabetic renal alterations | Exacerbation of diabetic renal alterations in mice lacking vasohibin-1.
Hinamoto N, Maeshima Y, Yamasaki H, Nasu T, Saito D, Watatani H, Ujike H, Tanabe K, Masuda K, Arata Y, Sugiyama H, Sato Y, Makino H., Free PMC Article | 06/27/2015 |
| VASH1 and VASH2 showed distinctive localization and opposing function on the fetoplacental vascularization. | Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.
Suenaga K, Kitahara S, Suzuki Y, Kobayashi M, Horie S, Sugawara J, Yaegashi N, Sato Y., Free PMC Article | 05/30/2015 |
| PKCdelta deficiency enhances neointimal formation, which is associated with delayed reendothelialization and involves increased cellular vasohibin-1 accumulation. | Protein kinase C{delta} deficiency accelerates neointimal lesions of mouse injured artery involving delayed reendothelialization and vasohibin-1 accumulation.
Bai X, Margariti A, Hu Y, Sato Y, Zeng L, Ivetic A, Habi O, Mason JC, Wang X, Xu Q. | 01/1/2011 |
| vasohibin1 is the first known intrinsic factor having broad-spectrum antilymphangiogenic activity | Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis.
Heishi T, Hosaka T, Suzuki Y, Miyashita H, Oike Y, Takahashi T, Nakamura T, Arioka S, Mitsuda Y, Takakura T, Hojo K, Matsumoto M, Yamauchi C, Ohta H, Sonoda H, Sato Y., Free PMC Article | 01/1/2011 |
| Overexpression of murine VASH1 inhibited angiogenic sprouting and supports vascular maturation processes in vivo. | Vasohibin inhibits angiogenic sprouting in vitro and supports vascular maturation processes in vivo.
Kern J, Steurer M, Gastl G, Gunsilius E, Untergasser G., Free PMC Article | 01/21/2010 |
| These results suggest that endogenous vasohibin-1 is involved in tumor angiogenesis and exogenous vasohibin-1 blocks sprouting angiogenesis by tumors, matures the remaining vessels, and enhances the antitumor effect of conventional chemotherapy | Vasohibin-1 expression in endothelium of tumor blood vessels regulates angiogenesis.
Hosaka T, Kimura H, Heishi T, Suzuki Y, Miyashita H, Ohta H, Sonoda H, Moriya T, Suzuki S, Kondo T, Sato Y., Free PMC Article | 01/21/2010 |
| These results suggest a role for VASH1 in negative feedback regulation of haematopoietic progenitors proliferation during recovery following bone marrow ablation. | Induction and expression of anti-angiogenic vasohibins in the hematopoietic stem/progenitor cell population.
Naito H, Kidoya H, Sato Y, Takakura N. | 01/21/2010 |
| Loss of vasohibin-1 is associated with persistent angiogenesis in the termination zone of endothelial cells. | Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis.
Kimura H, Miyashita H, Suzuki Y, Kobayashi M, Watanabe K, Sonoda H, Ohta H, Fujiwara T, Shimosegawa T, Sato Y. | 01/21/2010 |
| data support the hypothesis that vasohibin acts as a negative feedback regulator of neovascularization in the retina and suggest that suppression of VEGF receptor 2 may play some role in mediating its activity | Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization.
Shen J, Yang X, Xiao WH, Hackett SF, Sato Y, Campochiaro PA. | 01/21/2010 |
| vasohibin has an activity to prevent neointimal formation by inhibiting adventitial angiogenesis | Vasohibin prevents arterial neointimal formation through angiogenesis inhibition.
Yamashita H, Abe M, Watanabe K, Shimizu K, Moriya T, Sato A, Satomi S, Ohta H, Sonoda H, Sato Y. | 01/21/2010 |