| Congenital heart defects caused by FOXJ1. | Congenital heart defects caused by FOXJ1.
Padua MB, Helm BM, Wells JR, Smith AM, Bellchambers HM, Sridhar A, Ware SM., Free PMC Article | 07/12/2023 |
| Down-expression of Foxj1 on airway epithelium with impaired cilia architecture in non-cystic fibrosis bronchiectasis implies disease severity. | Down-expression of Foxj1 on airway epithelium with impaired cilia architecture in non-cystic fibrosis bronchiectasis implies disease severity.
Zou XL, Yang HL, Ding WW, Li HK, Zhou YQ, Zhang TT., Free PMC Article | 05/31/2023 |
| Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study. | Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study.
Weir A, Kang EY, Meagher NS, Nelson GS, Ghatage P, Lee CH, Riggan MJ, Gentry-Maharaj A, Ryan A, Singh N, Widschwendter M, Alsop J, Anglesio MS, Beckmann MW, Berger J, Bisinotto C, Boros J, Brand AH, Brenton JD, Brooks-Wilson A, Carney ME, Cunningham JM, Cushing-Haugen KL, Cybulski C, Elishaev E, Erber R, Fereday S, Fischer A, Paz-Ares L, Gayarre J, Gilks BC, Grube M, Harnett PR, Harris HR, Hartmann A, Hein A, Hendley J, Hernandez BY, Heublein S, Huang Y, Huzarski T, Jakubowska A, Jimenez-Linan M, Kennedy CJ, Kommoss FKF, Koziak JM, Kraemer B, Le ND, Lesnock J, Lester J, Lubiński J, Menkiszak J, Ney B, Olawaiye A, Orsulic S, Osorio A, Robles-Díaz L, Ruebner M, Shah M, Sharma R, Shvetsov YB, Steed H, Talhouk A, Taylor SE, Traficante N, Vierkant RA, Wang C, Wilkens LR, Winham SJ, Benitez J, Berchuck A, Bowtell DD, Candido Dos Reis FJ, Cook LS, DeFazio A, AOCs group, Doherty JA, Fasching PA, García MJ, Goode EL, Goodman MT, Gronwald J, Huntsman DG, Karlan BY, Kommoss S, Modugno F, Schildkraut JM, Sinn HP, Staebler A, Kelemen LE, Ford CE, Menon U, Pharoah PDP, Köbel M, Ramus SJ., Free PMC Article | 01/14/2023 |
| Autosomal dominant variants in FOXJ1 causing primary ciliary dyskinesia in two patients with obstructive hydrocephalus. | Autosomal dominant variants in FOXJ1 causing primary ciliary dyskinesia in two patients with obstructive hydrocephalus.
Shapiro AJ, Kaspy K, Daniels MLA, Stonebraker JR, Nguyen VH, Joyal L, Knowles MR, Zariwala MA., Free PMC Article | 03/5/2022 |
| Androglobin gene expression patterns and FOXJ1-dependent regulation indicate its functional association with ciliogenesis. | Androglobin gene expression patterns and FOXJ1-dependent regulation indicate its functional association with ciliogenesis.
Koay TW, Osterhof C, Orlando IMC, Keppner A, Andre D, Yousefian S, Suárez Alonso M, Correia M, Markworth R, Schödel J, Hankeln T, Hoogewijs D., Free PMC Article | 09/4/2021 |
| Knockdown of FOXJ1 inhibits the proliferation, migration, invasion, and glycolysis in laryngeal squamous cell carcinoma cells. | Knockdown of FOXJ1 inhibits the proliferation, migration, invasion, and glycolysis in laryngeal squamous cell carcinoma cells.
Liu L, Zhang P, Shao Y, Quan F, Li H. | 09/19/2020 |
| Heterozygous de novo mutations in FOXJ1. | De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry.
Wallmeier J, Frank D, Shoemark A, Nöthe-Menchen T, Cindric S, Olbrich H, Loges NT, Aprea I, Dougherty GW, Pennekamp P, Kaiser T, Mitchison HM, Hogg C, Carr SB, Zariwala MA, Ferkol T, Leigh MW, Davis SD, Atkinson J, Dutcher SK, Knowles MR, Thiele H, Altmüller J, Krenz H, Wöste M, Brentrup A, Ahrens F, Vogelberg C, Morris-Rosendahl DJ, Omran H., Free PMC Article | 04/4/2020 |
| TIM-3 and FOXJ1 exhibited abnormally high expression levels in prostate cancer. | Significance of the detection of TIM-3 and FOXJ1 in prostate cancer.
Lan Y, Hu X, Jiang K, Yuan W, Zheng F, Chen H. | 07/6/2019 |
| Downregulation and aberrant localization of FOXJ1 may be crucial characteristics of the allergic nasal mucosa. | Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa.
Peng Y, Chen Z, Guan WJ, Zhu Z, Tan KS, Hong H, Zi X, Zeng J, Li Y, Ong YK, Thong M, Shi L, Yang Q, Qiu Q, Wang DY. | 06/30/2018 |
| Our findings provide clues regarding the role of FOXJ1 as a tumor inducer in bladder cancer and an enhancer in glycolysis. Targeting FOXJ1 could be a potential therapeutic strategy in bladder cancer. | FOXJ1 promotes bladder cancer cell growth and regulates Warburg effect.
Xian S, Shang D, Kong G, Tian Y. | 12/30/2017 |
| Findings demonstrate that increased FOXJ1 contributes to the progression of CRC, which might be associated with the promotion effect of b-catenin nuclear translocation. | Forkhead Box Protein J1 (FOXJ1) is Overexpressed in Colorectal Cancer and Promotes Nuclear Translocation of β-Catenin in SW620 Cells.
Liu K, Fan J, Wu J., Free PMC Article | 06/3/2017 |
| In ependymomas and choroid plexus tumours, reduced expression of FOXJ1 and its ciliogenesis programme are markers of poor outcome | Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.
Abedalthagafi MS, Wu MP, Merrill PH, Du Z, Woo T, Sheu SH, Hurwitz S, Ligon KL, Santagata S., Free PMC Article | 08/13/2016 |
| Decreased FOXJ1 expression was correlated with clinic stage, lymph node metastasis, and distant metastasis, and lower FOXJ1 expression independently predicted shorter survival time in gastric carcinoma. | Decreased expression of FOXJ1 is a potential prognostic predictor for progression and poor survival of gastric cancer.
Wang J, Cai X, Xia L, Zhou J, Xin J, Liu M, Shang X, Liu J, Li X, Chen Z, Nie Y, Fan D. | 09/26/2015 |
| Both protein and mRNA levels of ciliogenesis-associated markers CP110, Foxj1, TAp73 were significantly increased in patients with nasal polyps versus those seen in control subjects and were positively correlated with cilia length | Impairment of cilia architecture and ciliogenesis in hyperplastic nasal epithelium from nasal polyps.
Li YY, Li CW, Chao SS, Yu FG, Yu XM, Liu J, Yan Y, Shen L, Gordon W, Shi L, Wang Y. | 02/7/2015 |
| By stimulating ciliogenesis with the transcription factor FOXJ1, it may be possible to maintain close to normal cilia length despite the stress of cigarette smoking. | FOXJ1 prevents cilia growth inhibition by cigarette smoke in human airway epithelium in vitro.
Brekman A, Walters MS, Tilley AE, Crystal RG., Free PMC Article | 01/3/2015 |
| Nanog-mediated cell migration and invasion involved its regulation of E-cadherin and FOXJ1. | Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers.
Siu MK, Wong ES, Kong DS, Chan HY, Jiang L, Wong OG, Lam EW, Chan KK, Ngan HY, Le XF, Cheung AN. | 10/19/2013 |
| FOXJ1 is an important regulator of cilia gene expression during ciliated cell differentiation, with RFX3 as a transcriptional co-activator to FOXJ1. | RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium.
Didon L, Zwick RK, Chao IW, Walters MS, Wang R, Hackett NR, Crystal RG., Free PMC Article | 10/19/2013 |
| FOXJ1 was overexpressed in HCCs and associated with histological grade and poor prognosis. | Expression of FOXJ1 in hepatocellular carcinoma: correlation with patients' prognosis and tumor cell proliferation.
Chen HW, Huang XD, Li HC, He S, Ni RZ, Chen CH, Peng C, Wu G, Wang GH, Wang YY, Zhao YH, Zhang YX, Shen AG, Wang HM. | 09/28/2013 |
| Rer1p depletion reduced ciliary length and function by increasing gamma-secretase complex assembly and activity and, consequently, enhancing Notch signaling as well as reducing Foxj1a expression. | Rer1p maintains ciliary length and signaling by regulating γ-secretase activity and Foxj1a levels.
Jurisch-Yaksi N, Rose AJ, Lu H, Raemaekers T, Munck S, Baatsen P, Baert V, Vermeire W, Scales SJ, Verleyen D, Vandepoel R, Tylzanowski P, Yaksi E, de Ravel T, Yost HJ, Froyen G, Arrington CB, Annaert W., Free PMC Article | 06/1/2013 |
| goblet cells formed in response to IL-13 treatment are in part or wholly derived from progenitors that express the ciliated cell marker, FOXJ1 | Goblet cells are derived from a FOXJ1-expressing progenitor in a human airway epithelium.
Turner J, Roger J, Fitau J, Combe D, Giddings J, Heeke GV, Jones CE. | 04/30/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesAssociation of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population.
Li CS, Zhang Q, Lim MK, Sheen DH, Shim SC, Kim JY, Lee SS, Yun KJ, Moon HB, Chung HT, Chae SC. Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis.
Li CS, Chae SC, Lee JH, Zhang Q, Chung HT, Li CS, Chae SC, Lee JH, Zhang Q, Chung HT. | 03/13/2008 |
| Single nucleotide polymorphisms were identified in FOXJ1 and a significant association was found with allergic rhinitis. | Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis.
Li CS, Chae SC, Lee JH, Zhang Q, Chung HT, Li CS, Chae SC, Lee JH, Zhang Q, Chung HT. | 01/21/2010 |