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    FOXD1 forkhead box D1 [ Homo sapiens (human) ]

    Gene ID: 2297, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    FOXD1 promotes chemotherapy resistance by enhancing cell stemness in colorectal cancer through beta-catenin nuclear localization.

    FOXD1 promotes chemotherapy resistance by enhancing cell stemness in colorectal cancer through β‑catenin nuclear localization.
    Feng WQ, Zhang YC, Gao H, Li WC, Miao YM, Xu ZF, Xu ZQ, Zhao JK, Zheng MH, Zong YP, Lu AG., Free PMC Article

    05/25/2023
    FOXD1-AS1 upregulates FOXD1 to promote oral squamous cell carcinoma progression.

    FOXD1-AS1 upregulates FOXD1 to promote oral squamous cell carcinoma progression.
    Ma Y, Han J, Luo X.

    02/11/2023
    FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.

    FOXD1 facilitates pancreatic cancer cell proliferation, invasion, and metastasis by regulating GLUT1-mediated aerobic glycolysis.
    Cai K, Chen S, Zhu C, Li L, Yu C, He Z, Sun C., Free PMC Article

    09/24/2022
    USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1.

    USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1.
    Zhang Q, Chen Z, Tang Q, Wang Z, Lu J, You Y, Wang H., Free PMC Article

    08/27/2022
    Combination of FOXD1 and Plk2: A novel biomarker for predicting unfavourable prognosis of colorectal cancer.

    Combination of FOXD1 and Plk2: A novel biomarker for predicting unfavourable prognosis of colorectal cancer.
    Zong Y, Miao Y, Li W, Zheng M, Xu Z, Gao H, Feng W, Xu Z, Zhao J, Shen L, Lu A., Free PMC Article

    06/25/2022
    The Expression and Survival Significance of FOXD1 in Lung Squamous Cell Carcinoma: A Meta-Analysis, Immunohistochemistry Validation, and Bioinformatics Analysis.

    The Expression and Survival Significance of FOXD1 in Lung Squamous Cell Carcinoma: A Meta-Analysis, Immunohistochemistry Validation, and Bioinformatics Analysis.
    Xie F, Li Y, Liang B., Free PMC Article

    05/28/2022
    Correlations between forkhead box D1 expression and clinicopathological characteristics of patients with bladder cancer and influence on biological behaviors of bladder cancer cells.", trans "Correlacion entre la expresion de Forkhead Box D1 y caracteristicas clinico-patologicas de pacientes con cancer de vejiga y su influencia en el comportamiento biologico de las celulas tumorales.

    Correlations between forkhead box D1 expression and clinicopathological characteristics of patients with bladder cancer and influence on biological behaviors of bladder cancer cells.
    Wang F, Yang J.

    04/23/2022
    Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.

    Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
    Fan L, Wang J, Deng P, Wang Y, Zhang A, Yang M, Zeng G., Free PMC Article

    04/16/2022
    Aberrant overexpression of transcription factor Forkhead box D1 predicts poor prognosis and promotes cancer progression in HNSCC.

    Aberrant overexpression of transcription factor Forkhead box D1 predicts poor prognosis and promotes cancer progression in HNSCC.
    Li J, Yan T, Wu X, Ke X, Li X, Zhu Y, Yang J, Li Z., Free PMC Article

    02/19/2022
    FOXD1 is a prognostic biomarker and correlated with macrophages infiltration in head and neck squamous cell carcinoma.

    FOXD1 is a prognostic biomarker and correlated with macrophages infiltration in head and neck squamous cell carcinoma.
    Liang H, Zhang C, Li C, Li C, Wang Y, Lin H., Free PMC Article

    02/5/2022
    FOXD1 expression in head and neck squamous carcinoma: a study based on TCGA, GEO and meta-analysis.

    FOXD1 expression in head and neck squamous carcinoma: a study based on TCGA, GEO and meta-analysis.
    Huang J, Liang B, Wang T., Free PMC Article

    02/5/2022
    LINC00641 contributes to nasopharyngeal carcinoma cell malignancy through FOXD1 upregulation at the post-transcriptional level.

    LINC00641 contributes to nasopharyngeal carcinoma cell malignancy through FOXD1 upregulation at the post-transcriptional level.
    Ren D, Lu J, Han X, Xiong W, Jiang H, Wei Y, Wang Y.

    01/22/2022
    Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.

    Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.
    Liu Q, Song X, Liu Z, Yu Z., Free PMC Article

    12/18/2021
    FOXD1-AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway.

    FOXD1-AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway.
    Wu Q, Ma J, Wei J, Meng W, Wang Y, Shi M., Free PMC Article

    11/22/2021
    FOXD1 promotes dedifferentiation and targeted therapy resistance in melanoma by regulating the expression of connective tissue growth factor.

    FOXD1 promotes dedifferentiation and targeted therapy resistance in melanoma by regulating the expression of connective tissue growth factor.
    Sun Q, Novak D, Hüser L, Poelchen J, Wu H, Granados K, Federico A, Liu K, Steinfass T, Vierthaler M, Umansky V, Utikal J.

    09/11/2021
    Forkhead box D1 promotes EMT and chemoresistance by upregulating lncRNA CYTOR in oral squamous cell carcinoma.

    Forkhead box D1 promotes EMT and chemoresistance by upregulating lncRNA CYTOR in oral squamous cell carcinoma.
    Chen S, Yang M, Wang C, Ouyang Y, Chen X, Bai J, Hu Y, Song M, Zhang S, Zhang Q.

    08/7/2021
    FOXD1 regulates cell division in clear cell renal cell carcinoma.

    FOXD1 regulates cell division in clear cell renal cell carcinoma.
    Bond KH, Fetting JL, Lary CW, Emery IF, Oxburgh L., Free PMC Article

    05/8/2021
    FOXD1, negatively regulated by miR-186, promotes the proliferation, metastasis and radioresistance of nasopharyngeal carcinoma cells.

    FOXD1, negatively regulated by miR-186, promotes the proliferation, metastasis and radioresistance of nasopharyngeal carcinoma cells.
    Zhang Y, Zhang W.

    04/17/2021
    miR-30a inhibits androgen-independent growth of prostate cancer via targeting MYBL2, FOXD1, and SOX4.

    miR-30a inhibits androgen-independent growth of prostate cancer via targeting MYBL2, FOXD1, and SOX4.
    Li X, Jiao M, Hu J, Qi M, Zhang J, Zhao M, Liu H, Xiong X, Dong X, Han B.

    08/15/2020
    Investigated forkhead box D1 (FOXD1) gene mutations in patients affected by repeated implantation failure (RIF), intra-uterine growth restriction(IUGR), and preeclampsia )PE) by direct sequencing and bioinformatics analysis. Results argue in favour of FOXD1 mutations' central role in recurrent pregnancy loss (RPL), RIF, IUGR and PE.

    FOXD1 mutations are related to repeated implantation failure, intra-uterine growth restriction and preeclampsia.
    Quintero-Ronderos P, Jiménez KM, Esteban-Pérez C, Ojeda DA, Bello S, Fonseca DJ, Coronel MA, Moreno-Ortiz H, Sierra-Díaz DC, Lucena E, Barbaux S, Vaiman D, Laissue P., Free PMC Article

    07/11/2020
    long noncoding RNA POU3 F3, induced by transcription factor SP1, acts as an oncogene in the cervical cancer tumorigenesis via regulating miR-127-5p/FOXD1 axis.

    SP1-mediated long noncoding RNA POU3F3 accelerates the cervical cancer through miR-127-5p/FOXD1.
    Chang S, Sun L, Feng G.

    01/25/2020
    YAP cooperated with TEA domain transcriptional factor (TEAD) to activate the expression of forkhead box D1 (FOXD1), a geroprotective protein. YAP deficiency led to the down-regulation of FOXD1.

    Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.
    Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu FX, Wu J, Wang S, Izpisua Belmonte JC, Chan P, Qu J, Tang F, Liu GH., Free PMC Article

    01/11/2020
    Suppression of miR-92a-1-5p and restoration of FOXD1 may be a preventive approach for gastric IM in patients with bile regurgitation.

    MicroRNA-92a-1-5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia.
    Li T, Guo H, Li H, Jiang Y, Zhuang K, Lei C, Wu J, Zhou H, Zhu R, Zhao X, Lu Y, Shi C, Nie Y, Wu K, Yuan Z, Fan DM, Shi Y., Free PMC Article

    10/19/2019
    FOXD1 may influence invasion and migration via indirect regulation of MMP9 and RAC1B alternative splicing in melanoma cells.

    Loss of neural crest-associated gene FOXD1 impairs melanoma invasion and migration via RAC1B downregulation.
    Wu H, Larribère L, Sun Q, Novak D, Sachindra S, Granados K, Umansky V, Utikal J.

    02/23/2019
    Mechanistic analyses revealed that FOXD1 expressed its oncogenic characteristics through activating Vimentin in non-small cell lung cancer cells.

    FOXD1 Promotes Cell Growth and Metastasis by Activation of Vimentin in NSCLC.
    Li D, Fan S, Yu F, Zhu X, Song Y, Ye M, Fan L, Lv Z.

    02/2/2019
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