| Acyl-CoA synthetase 6 controls rod photoreceptor function and survival by shaping the phospholipid composition of retinal membranes. | Acyl-CoA synthetase 6 controls rod photoreceptor function and survival by shaping the phospholipid composition of retinal membranes.
Wang Y, Becker S, Finkelstein S, Dyka FM, Liu H, Eminhizer M, Hao Y, Brush RS, Spencer WJ, Arshavsky VY, Ash JD, Du J, Agbaga MP, Vinberg F, Ellis JM, Lobanova ES., Free PMC Article | 10/2/2024 |
| Long chain acyl-CoA synthetase 6 facilitates the local distribution of di-docosahexaenoic acid- and ultra-long-chain-PUFA-containing phospholipids in the retina to support normal visual function in mice. | Long chain acyl-CoA synthetase 6 facilitates the local distribution of di-docosahexaenoic acid- and ultra-long-chain-PUFA-containing phospholipids in the retina to support normal visual function in mice.
Kuroha S, Katada Y, Isobe Y, Uchino H, Shishikura K, Nirasawa T, Tsubota K, Negishi K, Kurihara T, Arita M. | 08/19/2023 |
| Ectopic Acsl6 Overexpression Partially Improves Isoproterenol-Induced Cardiac Hypertrophy In Vivo and Cardiomyocyte Hypertrophy In Vitro. | Ectopic Acsl6 Overexpression Partially Improves Isoproterenol-Induced Cardiac Hypertrophy In Vivo and Cardiomyocyte Hypertrophy In Vitro.
Xu L, Liu Q, Long T, Peng L, Li F, Sun Z, Xie Q. | 12/17/2022 |
| Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging. | Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging.
Fernandez RF, Pereyra AS, Diaz V, Wilson ES, Litwa KA, Martínez-Gardeazabal J, Jackson SN, Brenna JT, Hermann BP, Eells JB, Ellis JM., Free PMC Article | 02/19/2022 |
| Acyl-CoA synthetase 6 regulates DHA and DPA composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice | Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice.
Shishikura K, Kuroha S, Matsueda S, Iseki H, Matsui T, Inoue A, Arita M., Free PMC Article | 02/26/2021 |
| Suppression of long chain acyl-CoA synthetase blocks intracellular fatty acid flux and glucose uptake in skeletal myotubes. | Suppression of long chain acyl-CoA synthetase blocks intracellular fatty acid flux and glucose uptake in skeletal myotubes.
Jung YH, Bu SY. | 10/24/2020 |
| ACSL6 is essential for germ cell DHA enrichment and is required for normal spermatogenesis and male fertility. | Acyl-CoA synthetase 6 enriches seminiferous tubules with the ω-3 fatty acid docosahexaenoic acid and is required for male fertility in the mouse.
Hale BJ, Fernandez RF, Kim SQ, Diaz VD, Jackson SN, Liu L, Brenna JT, Hermann BP, Geyer CB, Ellis JM., Free PMC Article | 05/23/2020 |
| Acsl6 knockout mice demonstrate motor impairments, altered glutamate metabolism, and increased astrogliosis and microglia activation. | Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain.
Fernandez RF, Kim SQ, Zhao Y, Foguth RM, Weera MM, Counihan JL, Nomura DK, Chester JA, Cannon JR, Ellis JM., Free PMC Article | 02/9/2019 |
| variations in the ACSL6 gene may contribute to the quantity of cigarettes smoked | ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure.
Chen J, Brunzell DH, Jackson K, van der Vaart A, Ma JZ, Payne TJ, Sherva R, Farrer LA, Gejman P, Levinson DF, Holmans P, Aggen SH, Damaj I, Kuo PH, Webb BT, Anton R, Kranzler HR, Gelernter J, Li MD, Kendler KS, Chen X., Free PMC Article | 04/28/2012 |
| Long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation. | A novel murine long-chain acyl-CoA synthetase expressed in brain participates in neuronal cell proliferation.
Kee HJ, Koh JT, Yang SY, Lee ZH, Baik YH, Kim KK. | 01/21/2010 |
| Acsl6 promoter 1 (mAcsl6_pr1) region has a negative regulatory function | Alternative promotion of the mouse acyl-CoA synthetase 6 (mAcsl6) gene mediates the expression of multiple transcripts with 5'-end heterogeneity: genetic organization of mAcsl6 variants.
Lee EJ, Kim HC, Cho YY, Byun SJ, Lim JM, Ryoo ZY. | 01/21/2010 |