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    ESRRA estrogen related receptor alpha [ Homo sapiens (human) ]

    Gene ID: 2101, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Silencing of ERRalpha gene represses cell proliferation and induces apoptosis in human skin fibroblasts.

    Silencing of ERRα gene represses cell proliferation and induces apoptosis in human skin fibroblasts.
    Nanashima N, Norikura T, Nakano M, Hata C, Horie K., Free PMC Article

    11/5/2024
    ERRalpha and ERRgamma coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation.

    ERRα and ERRγ coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation.
    Sato K, Takayama KI, Saito Y, Inoue S.,

    09/12/2024
    Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks.

    Estrogen-related receptor alpha promotes thyroid tumor cell survival via a tumor subtype-specific regulation of target gene networks.
    Chen W, Song YS, Lee HS, Lin CW, Lee J, Kang YE, Kim SK, Kim SY, Park YJ, Park JI.

    07/30/2024
    Estrogen-related receptor alpha (ERRalpha) promotes the migration, invasion and angiogenesis of breast cancer stem cell-like cells.

    Estrogen-related receptor alpha (ERRα) promotes the migration, invasion and angiogenesis of breast cancer stem cell-like cells.
    Muduli K, Pradhan J, Prusty M, Samal AP, Reddy KS, Elangovan S.

    04/3/2024
    Estrogen related receptor alpha: Potential modulator of age-related macular degeneration.

    Estrogen related receptor alpha: Potential modulator of age-related macular degeneration.
    Somers FM, Malek G.,

    03/19/2024
    ERRalpha: unraveling its role as a key player in cell migration.

    ERRα: unraveling its role as a key player in cell migration.
    Vanacker JM, Forcet C.

    02/5/2024
    Estrogen-Related Receptor Alpha (ERRalpha) Promotes Cancer Stem Cell-Like Characteristics in Breast Cancer.

    Estrogen-Related Receptor Alpha (ERRα) Promotes Cancer Stem Cell-Like Characteristics in Breast Cancer.
    Muduli K, Prusty M, Pradhan J, Samal AP, Sahu B, Roy DS, Reddy KS, Elangovan S.

    12/1/2023
    Exome Sequencing Implicates DGKZ , ESRRA , and GXYLT1 for Modulating Granuloma Formation in Crohn Disease.

    Exome Sequencing Implicates DGKZ , ESRRA , and GXYLT1 for Modulating Granuloma Formation in Crohn Disease.
    Harris RA, Bush AH, Eagar TN, Qian J, Greenwood MP, Opekun AR, Baldassano R, Guthery SL, Noe JD, Otley A, Rosh JR, Kugathasan S, Kellermayer R., Free PMC Article

    08/22/2023
    The Role of the Estrogen-Related Receptor Alpha (ERRa) in Hypoxia and Its Implications for Cancer Metabolism.

    The Role of the Estrogen-Related Receptor Alpha (ERRa) in Hypoxia and Its Implications for Cancer Metabolism.
    Chaltel-Lima L, Domínguez F, Domínguez-Ramírez L, Cortes-Hernandez P., Free PMC Article

    05/19/2023
    ERRalpha Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.

    ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
    Tang S, Ma J, Su P, Lei H, Tong Y, Cai L, Xu S, Mao X, Sun P., Free PMC Article

    03/27/2023
    New insights into cholesterol-mediated ERRalpha activation in breast cancer progression and pro-tumoral microenvironment orchestration.

    New insights into cholesterol-mediated ERRα activation in breast cancer progression and pro-tumoral microenvironment orchestration.
    Brindisi M, Frattaruolo L, Fiorillo M, Dolce V, Sotgia F, Lisanti MP, Cappello AR.

    03/23/2023
    Multifaceted Transcriptional Network of Estrogen-Related Receptor Alpha in Health and Disease.

    Multifaceted Transcriptional Network of Estrogen-Related Receptor Alpha in Health and Disease.
    Cerutti C, Shi JR, Vanacker JM., Free PMC Article

    03/15/2023
    ERRalpha Attenuates Vascular Inflammation via Enhanced NFkappaB Degradation Pathway.

    ERRα Attenuates Vascular Inflammation via Enhanced NFκB Degradation Pathway.
    Yamamoto H, Tanaka Y, Sawada M, Kihara S.

    01/21/2023
    Association of Irisin/FNDC5 with ERRalpha and PGC-1alpha Expression in NSCLC.

    Association of Irisin/FNDC5 with ERRα and PGC-1α Expression in NSCLC.
    Nowińska K, Jabłońska K, Ciesielska U, Piotrowska A, Haczkiewicz-Leśniak K, Pawełczyk K, Podhorska-Okołów M, Dzięgiel P., Free PMC Article

    12/10/2022
    IGF2BP1-regulated expression of ERRalpha is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells.

    IGF2BP1-regulated expression of ERRα is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells.
    He Q, Hao P, He G, Mai H, Liu W, Zhang W, Zhang K, Zhong G, Guo R, Yu C, Li Y, Wong C, Chen Q, Chen Y., Free PMC Article

    08/27/2022
    ERRalpha expression in ovarian cancer and promotes ovarian cancer cells migration in vitro.

    ERRα expression in ovarian cancer and promotes ovarian cancer cells migration in vitro.
    Huang W, Chen L, Sun P.

    06/11/2022
    Computational identification of new potential transcriptional partners of ERRalpha in breast cancer cells: specific partners for specific targets.

    Computational identification of new potential transcriptional partners of ERRα in breast cancer cells: specific partners for specific targets.
    Cerutti C, Zhang L, Tribollet V, Shi JR, Brillet R, Gillet B, Hughes S, Forcet C, Shi TL, Vanacker JM., Free PMC Article

    05/7/2022
    Branched-chain amino acid metabolism is regulated by ERRalpha in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.

    Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.
    Sjögren RJO, Rizo-Roca D, Chibalin AV, Chorell E, Furrer R, Katayama S, Harada J, Karlsson HKR, Handschin C, Moritz T, Krook A, Näslund E, Zierath JR., Free PMC Article

    04/9/2022
    Evaluation of EZH2 and ERRalpha in colorectal carcinoma: an immunohistochemical study.

    Evaluation of EZH2 and ERRα in colorectal carcinoma: an immunohistochemical study.
    Abou Gabal H, Ahmed N, Meckawy G, Yassin R, Hakim S.

    01/29/2022
    Triple-negative breast lobular carcinoma: a luminal androgen receptor carcinoma with specific ESRRA mutations.

    Triple-negative breast lobular carcinoma: a luminal androgen receptor carcinoma with specific ESRRA mutations.
    Bergeron A, MacGrogan G, Bertaut A, Ladoire S, Arveux P, Desmoulins I, Bonnefoi H, Loustalot C, Auriol S, Beltjens F, Degrolard-Courcet E, Charon-Barra C, Richard C, Boidot R, Arnould L., Free PMC Article

    01/29/2022
    Declined expressions of vast mitochondria-related genes represented by CYCS and transcription factor ESRRA in skeletal muscle aging.

    Declined expressions of vast mitochondria-related genes represented by CYCS and transcription factor ESRRA in skeletal muscle aging.
    Kan J, Hu Y, Ge Y, Zhang W, Lu S, Zhao C, Zhang R, Liu Y., Free PMC Article

    12/18/2021
    Comprehensive Analysis of ESRRA in Endometrial Cancer.

    Comprehensive Analysis of ESRRA in Endometrial Cancer.
    Wang S, Huo X., Free PMC Article

    11/27/2021
    PI3K/AKT phosphorylation activates ERRalpha by upregulating PGC1alpha and PGC1beta in gallbladder cancer.

    PI3K/AKT phosphorylation activates ERRα by upregulating PGC‑1α and PGC‑1β in gallbladder cancer.
    Wang L, Yang M, Jin H., Free PMC Article

    10/30/2021
    Estrogen-related receptors: novel potential regulators of osteoarthritis pathogenesis.

    Estrogen-related receptors: novel potential regulators of osteoarthritis pathogenesis.
    Tang J, Liu T, Wen X, Zhou Z, Yan J, Gao J, Zuo J., Free PMC Article

    10/2/2021
    FBXL10 promotes ERRalpha protein stability and proliferation of breast cancer cells by enhancing the mono-ubiquitylation of ERRalpha.

    FBXL10 promotes ERRα protein stability and proliferation of breast cancer cells by enhancing the mono-ubiquitylation of ERRα.
    Yang Y, Li S, Li B, Li Y, Xia K, Aman S, Yang Y, Ahmad B, Zhao B, Wu H.

    08/7/2021
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