| CPEB3 Maintains Developmental Competence of the Oocyte. | CPEB3 Maintains Developmental Competence of the Oocyte.
Lamacova L, Jansova D, Jiang Z, Dvoran M, Aleshkina D, Iyyappan R, Jindrova A, Fan HY, Jiao Y, Susor A., Free PMC Article | 09/6/2024 |
| MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration. | MicroRNA-92a-CPEB3 axis protects neurons against inflammatory neurodegeneration.
Winkler I, Engler JB, Vieira V, Bauer S, Liu YH, Di Liberto G, Grochowska KM, Wagner I, Bier J, Bal LC, Rothammer N, Meurs N, Egervari K, Schattling B, Salinas G, Kreutz MR, Huang YS, Pless O, Merkler D, Friese MA., Free PMC Article | 03/13/2024 |
| Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory. | Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory.
Chen CC, Han J, Chinn CA, Rounds JS, Li X, Nikan M, Myszka M, Tong L, Passalacqua LFM, Bredy T, Wood MA, Luptak A., Free PMC Article | 03/11/2024 |
| CPEB3 suppresses gastric cancer progression by inhibiting ADAR1-mediated RNA editing via localizing ADAR1 mRNA to P bodies. | CPEB3 suppresses gastric cancer progression by inhibiting ADAR1-mediated RNA editing via localizing ADAR1 mRNA to P bodies.
Chen J, Li L, Liu TY, Fu HF, Lai YH, Lei X, Xu JF, Yu JS, Xia YJ, Zhang TH, Yang DJ, He YL. | 10/15/2022 |
| CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X. | CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.
Hwang JY, Monday HR, Yan J, Gompers A, Buxbaum AR, Sawicka KJ, Singer RH, Castillo PE, Zukin RS., Free PMC Article | 06/18/2022 |
| CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis. | CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis.
Wang H, Peng D, Gan M, He Z, Kuang Y. | 05/7/2022 |
| MicroRNA-21-5p Reduces Hypoxia/Reoxygenation-Induced Neuronal Cell Damage through Negative Regulation of CPEB3. | MicroRNA-21-5p Reduces Hypoxia/Reoxygenation-Induced Neuronal Cell Damage through Negative Regulation of CPEB3.
Wang B, Yu P, Lin W, Zhai Z., Free PMC Article | 04/2/2022 |
| CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency. | CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency.
E F, Zhang H, Yin W, Wang C, Liu Y, Li Y, Wang L, Wu Y, Zhang R, Zou C, Song T, Matunda C, Zou C, Gao X., Free PMC Article | 03/26/2022 |
| CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice. | CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice.
Lu WH, Chao HW, Lin PY, Lin SH, Liu TH, Chen HW, Huang YS., Free PMC Article | 09/18/2021 |
| Topological regulation of synaptic AMPA receptor expression by the RNA-binding protein CPEB3 has been demonstrated. | Topological Regulation of Synaptic AMPA Receptor Expression by the RNA-Binding Protein CPEB3.
Savtchouk I, Sun L, Bender CL, Yang Q, Szabó G, Gasparini S, Liu SJ., Free PMC Article | 11/18/2017 |
| CPEB3-regulated translation of TRPV1 RNA may play a role in fine-tuning thermal sensitivity of nociceptors. | CPEB3 Deficiency Elevates TRPV1 Expression in Dorsal Root Ganglia Neurons to Potentiate Thermosensation.
Fong SW, Lin HC, Wu MF, Chen CC, Huang YS., Free PMC Article | 07/30/2016 |
| CPEB3 interacts with the actin cytoskeleton in yeast and at mouse synapses. CPEB3 is a functional prion with a tripartite prion domain architecture. | The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton.
Stephan JS, Fioriti L, Lamba N, Colnaghi L, Karl K, Derkatch IL, Kandel ER. | 03/26/2016 |
| CPEB3 is SUMOylated in hippocampal neurons. CPEB3 regulates SUMO-2 translation. | SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.
Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER., Free PMC Article | 03/26/2016 |
| The main finding of our study is that CPEB3-mediated protein synthesis is required for long-term hippocampal-based memory storage. | The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3.
Fioriti L, Myers C, Huang YY, Li X, Stephan JS, Trifilieff P, Colnaghi L, Kosmidis S, Drisaldi B, Pavlopoulos E, Kandel ER. | 09/5/2015 |
| Cpeb3 null mice exhibited enhanced short-term fear memory and translationally elevated PSD95, NMDA receptors and GluA1. | Deletion of CPEB3 enhances hippocampus-dependent memory via increasing expressions of PSD95 and NMDA receptors.
Chao HW, Tsai LY, Lu YL, Lin PY, Huang WH, Chou HJ, Lu WH, Lin HC, Lee PT, Huang YS., Free PMC Article | 12/28/2013 |
| cleavage of CPEB3 by NMDA-activated calpain 2 accounts for the activity-related translation of CPEB3-targeted RNAs | Calpain 2 activated through N-methyl-D-aspartic acid receptor signaling cleaves CPEB3 and abrogates CPEB3-repressed translation in neurons.
Wang CF, Huang YS., Free PMC Article | 10/20/2012 |
| These results suggest a model whereby Neuralized1-dependent ubiquitination facilitates hippocampal plasticity and hippocampal-dependent memory storage by modulating the activity of CPEB3 and CPEB3-dependent protein synthesis and synapse formation. | Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage.
Pavlopoulos E, Trifilieff P, Chevaleyre V, Fioriti L, Zairis S, Pagano A, Malleret G, Kandel ER., Free PMC Article | 02/4/2012 |
| CPEB3 has a novel function in the nucleus as to suppress Stat5b-dependent EGFR gene transcription | A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.
Peng SC, Lai YT, Huang HY, Huang HD, Huang YS., Free PMC Article | 02/26/2011 |
| show that CPEB3 expression is increased in a time-dependent manner during the course of postnatal development, and CPEB3 is localized mostly in the inner retina, including retinal ganglion cells. | Characterization of the transcripts and protein isoforms for cytoplasmic polyadenylation element binding protein-3 (CPEB3) in the mouse retina.
Wang XP, Cooper NG., Free PMC Article | 03/15/2010 |
| CPEB3 is a sequence-specific translational regulatory protein. | CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA.
Huang YS, Kan MC, Lin CL, Richter JD., Free PMC Article | 01/21/2010 |
| CPEB3 is expressed in the principal cell layers of the hippocampus | Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus.
Theis M, Si K, Kandel ER., Free PMC Article | 01/21/2010 |