| Association of ERCC1 and XPF polymorphisms with pediatric glioma susceptibility. | Association of ERCC1 and XPF polymorphisms with pediatric glioma susceptibility.
Chen Y, Liao Y, Jia X, Lin H, Miao L, Yuan L, Huang X, Zhou J, Bian J, Zhuo Z., Free PMC Article | 04/24/2023 |
| Association of XPG rs17655G>C and XPF rs1799801T>C Polymorphisms with Susceptibility to Cutaneous Malignant Melanoma: Evidence from a Case-Control Study, Systematic Review and Meta-Analysis | Association of XPG rs17655G>C and XPF rs1799801T>C Polymorphisms with Susceptibility to Cutaneous Malignant Melanoma: Evidence from a Case-Control Study, Systematic Review and Meta-Analysis.
Mohammadreza Niktabar S, Alireza Dastgheib S, Heiranizadeh N, Kargar S, Raee-Ezzabadi A, Jarahzadeh MH, Mohsen Miresmaeili S, Zare-Shehneh M, Neamatzadeh H. | 03/12/2023 |
| Association of nonsynonymous SNPs of nucleotide excision repair genes ERCC4 rs1800067 (G/A) and ERCC5 rs17655 (G/C) as predisposing risk factors for gallbladder cancer. | Association of nonsynonymous SNPs of nucleotide excision repair genes ERCC4 rs1800067 (G/A) and ERCC5 rs17655 (G/C) as predisposing risk factors for gallbladder cancer.
Anjali K, Kumar T, Kumar P, Narayan G, Singh S. | 11/5/2022 |
| The link of ERCC2 rs13181 and ERCC4 rs2276466 polymorphisms with breast cancer in the Bangladeshi population. | The link of ERCC2 rs13181 and ERCC4 rs2276466 polymorphisms with breast cancer in the Bangladeshi population.
Sahaba SA, Rashid MA, Islam MS, Nahid NA, Apu MNH, Sultana TN, Chaity NI, Hasan MM, Islam MS. | 04/9/2022 |
| The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer. | The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.
Sreekumar R, Al-Saihati H, Emaduddin M, Moutasim K, Mellone M, Patel A, Kilic S, Cetin M, Erdemir S, Navio MS, Lopez MA, Curtis N, Yagci T, Primrose JN, Price BD, Berx G, Thomas GJ, Tulchinsky E, Mirnezami A, Sayan AE., Free PMC Article | 04/2/2022 |
| F-circEA1 regulates cell proliferation and apoptosis through ALK downstream signaling pathway in non-small cell lung cancer. | F-circEA1 regulates cell proliferation and apoptosis through ALK downstream signaling pathway in non-small cell lung cancer.
Huo Y, Lv T, Ye M, Zhu S, Liu J, Liu H, Song Y., Free PMC Article | 02/5/2022 |
| Contribution of XPD and XPF Polymorphisms to Susceptibility of Non-Small Cell Lung Cancer in High-Altitude Areas. | Contribution of XPD and XPF Polymorphisms to Susceptibility of Non-Small Cell Lung Cancer in High-Altitude Areas.
Li M, Chen R, Ji B, Fan C, Wang G, Yue C, Li G. | 12/4/2021 |
| XPF -673C>T variation is associated with the susceptibility to breast cancer. | XPF -673C>T variation is associated with the susceptibility to breast cancer.
Wu H, Song Q, Zhang Z, Li A, Zhu X, Yang Z, Zhang X. | 10/30/2021 |
| Distribution and susceptibility of ERCC1/XPF gene polymorphisms in Han and Uygur women with breast cancer in Xinjiang, China. | Distribution and susceptibility of ERCC1/XPF gene polymorphisms in Han and Uygur women with breast cancer in Xinjiang, China.
Li H, Zhou L, Ma J, Zhu Y, Fan J, Li N, Zheng Y, Sha T, Zhai Z, Ma B, Dai Z., Free PMC Article | 08/7/2021 |
| Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance. | Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance.
Lee JH, Suh JH, Kang HJ, Choi SY, Jung SW, Lee-Kwon W, Park SA, Kim H, Ye BJ, Yoo EJ, Jeong GW, Park NH, Kwon HM., Free PMC Article | 06/12/2021 |
| SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions. | SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions.
Ishimoto R, Tsuzuki Y, Matsumura T, Kurashige S, Enokitani K, Narimatsu K, Higa M, Sugimoto N, Yoshida K, Fujita M., Free PMC Article | 05/22/2021 |
| DNA base excision repair and nucleotide excision repair proteins in malignant salivary gland tumors. | DNA base excision repair and nucleotide excision repair proteins in malignant salivary gland tumors.
Felix FA, da Silva LP, Lopes MLDS, Sobral APV, Freitas RA, de Souza LB, Barboza CAG. | 02/6/2021 |
| Impact of XPF rs2276466 polymorphism on cancer susceptibility: a meta-analysis. | Impact of XPF rs2276466 polymorphism on cancer susceptibility: a meta-analysis.
Liu Y, Liu K, Zhao X, Sun Y, Ma N, Tang L, Yang H, Gao X, Yan L, Yuan M, Wang B, Zhang X, Jia J., Free PMC Article | 08/22/2020 |
| Our results confirm its dependence on XPA in NER and furthermore show that its engagement in ICLR is dependent on FANCD2. Interestingly, we find that two ICLR-defective XPF mutants (R689S and S786F) are less well recruited to ICLs. These studies highlight the differential mechanisms that regulate ERCC1-XPF activity in DNA repair | ERCC1-XPF targeting to psoralen-DNA crosslinks depends on XPA and FANCD2.
Sabatella M, Pines A, Slyskova J, Vermeulen W, Lans H., Free PMC Article | 05/30/2020 |
| DCAF7 is a novel regulator of ERCC1-XPF protein level and cellular nucleotide excision repair activity. | DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair.
Kawara H, Akahori R, Wakasugi M, Sancar A, Matsunaga T., Free PMC Article | 05/30/2020 |
| TIP60 directly acetylates XPF at Lysine 911 following ultraviolet irradiation and that this acetylation is required for XPF-ERCC1 complex assembly and subsequent activation. | Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation.
Wang J, He H, Chen B, Jiang G, Cao L, Jiang H, Zhang G, Chen J, Huang J, Yang B, Zhou C, Liu T., Free PMC Article | 05/23/2020 |
| ERCC4 rs6498486 polymorphism is associated with colorectal cancer risk. | Association between nucleotide excision repair gene polymorphism and colorectal cancer risk.
Zhang Y, Wu S, Zhou X, Huang F, Chen R, Wang Y, Wu J., Free PMC Article | 03/14/2020 |
| results suggest a potential involvement of APE-1, XRCC-1 and XPF proteins in the pathogenesis of benign epithelial odontogenic lesions, especially in those with more aggressive biological behavior | Immunoexpression of DNA base excision repair and nucleotide excision repair proteins in ameloblastomas, syndromic and non-syndromic odontogenic keratocysts and dentigerous cysts.
Santos HBP, Morais EF, Cavalcante RB, Nogueira RLM, Nonaka CFW, Souza LB, Freitas RA. | 02/8/2020 |
| The binding of SLX4IP to both SLX4 and XPF-ERCC1 not only is vital for maintaining the stability of SLX4IP protein, but also promotes the interaction between SLX4 and XPF-ERCC1, especially after DNA damage. Collectively, these results demonstrate a new regulatory role for SLX4IP in maintaining an efficient SLX4-XPF-ERCC1 complex in interstrand crosslinks (ICLs) repair. | SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.
Zhang H, Chen Z, Ye Y, Ye Z, Cao D, Xiong Y, Srivastava M, Feng X, Tang M, Wang C, Tainer JA, Chen J., Free PMC Article | 12/14/2019 |
| The results indicate that core nucleotide excision repair (NER) components XPA and XPF are equally required and that both global genome (GG-NER) and transcription coupled (TC-NER) subpathways contribute to the repair. | Nucleotide excision repair of abasic DNA lesions.
Kitsera N, Rodriguez-Alvarez M, Emmert S, Carell T, Khobta A., Free PMC Article | 12/7/2019 |
| Functional studies in human XPF-KO isogenic cells demonstrate that a defined cellular phenotype cannot be easily correlated to each pathogenic XPF mutation. Substituted positions along XPF sequences are not predictive of cellular phenotype nor reflect a particular disease. | Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders.
Marín M, Ramírez MJ, Carmona MA, Jia N, Ogi T, Bogliolo M, Surrallés J., Free PMC Article | 11/16/2019 |
| XPF and MUS81 merit further validation in prospective clinical trials as biomarkers that may predict clinical response of esophageal adenocarcinoma (EAC) to oxaliplatin-based chemotherapy. | Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.
MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM, Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma RA., Free PMC Article | 10/19/2019 |
| we investigated how specific XPF mutations found in patients affected with xeroderma pigmentosum(XP) , XP combined with Cockayne syndrome or Fanconi anemia impair the activity of the ERCC1-XPF complex in response to DNA damage induction by UV irradiation. We show that XPF with an XP mutation is inefficiently recruited into the NER machinery but retains repair activity. | Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features.
Sabatella M, Theil AF, Ribeiro-Silva C, Slyskova J, Thijssen K, Voskamp C, Lans H, Vermeulen W., Free PMC Article | 06/29/2019 |
| XPF rs1799801 was associated with severe preeclampsia and early-onset preeclampsia in Chinese Han Women. | The relationship between DNA repair genes (XPA, XPF, XPG) polymorphism and the risk of preeclampsia in Chinese Han Women.
Wang H, Liu J, Zhang R, Liu Y, Ren X, Gao K, Zhao C, Liu S. | 02/2/2019 |
| Study provides evidence that Replication forks can break quickly in S-phase upon DNA replication stress induction by an endonucleolytic mechanism independent of MUS81. Two nucleases ARTEMIS and XPF-ERCC1 are responsible for this Rapid-Replication Fork Breakage (RRFB) which takes place during S and G2 phases of the cell cycle. | DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF.
Bétous R, Goullet de Rugy T, Pelegrini AL, Queille S, de Villartay JP, Hoffmann JS., Free PMC Article | 01/19/2019 |