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    S100a9 S100 calcium binding protein A9 (calgranulin B) [ Mus musculus (house mouse) ]

    Gene ID: 20202, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Dysregulated S100A9 Expression Impairs Matrix Deposition in Chronic Wounds.

    Dysregulated S100A9 Expression Impairs Matrix Deposition in Chronic Wounds.
    Franz S, Torregrossa M, Anderegg U, Ertel A, Saalbach A., Free PMC Article

    10/7/2024
    S100A9 deletion in microglia/macrophages ameliorates brain injury through the STAT6/PPARgamma pathway in ischemic stroke.

    S100A9 deletion in microglia/macrophages ameliorates brain injury through the STAT6/PPARγ pathway in ischemic stroke.
    Liu X, Wang J, Jin J, Hu Q, Zhao T, Wang J, Gao J, Man J., Free PMC Article

    09/13/2024
    Cmtm4 deficiency exacerbates colitis by inducing gut dysbiosis and S100a8/9 expression.

    Cmtm4 deficiency exacerbates colitis by inducing gut dysbiosis and S100a8/9 expression.
    Meng Q, Ning J, Lu J, Zhang J, Zu M, Zhang J, Han X, Zheng H, Gong Y, Hao X, Xiong Y, Gu F, Han W, Fu W, Wang J, Ding S.

    09/12/2024
    Neutrophil-secreted S100A8/A9 participates in fatty liver injury and fibrosis by promoting myofibroblast migration.

    Neutrophil-secreted S100A8/A9 participates in fatty liver injury and fibrosis by promoting myofibroblast migration.
    Chang N, Liu Y, Li W, Ma Y, Zhou X, Zhao X, Yang L, Li L.

    09/9/2024
    Usp14 deficiency removes alpha-synuclein by regulating S100A8/A9 in Parkinson's disease.

    Usp14 deficiency removes α-synuclein by regulating S100A8/A9 in Parkinson's disease.
    Ding L, Lu L, Zheng S, Zhang Z, Huang X, Ma R, Zhang M, Xu Z, Chen M, Guo Z, Zhu S, Gong J, Mao H, Zhang W, Xu P., Free PMC Article

    09/4/2024
    S100a8/9 (S100 Calcium Binding Protein a8/9) Promotes Cardiac Hypertrophy Via Upregulation of FGF23 (Fibroblast Growth Factor 23) in Mice.

    S100a8/9 (S100 Calcium Binding Protein a8/9) Promotes Cardiac Hypertrophy Via Upregulation of FGF23 (Fibroblast Growth Factor 23) in Mice.
    Yuan YP, Shen ZY, Teng T, Xu SC, Kong CY, Zeng XF, A Hofmann Bowman M, Yan L., Free PMC Article

    07/26/2024
    S100A8/9 modulates perturbation and glycolysis of macrophages in allergic asthma mice.

    S100A8/9 modulates perturbation and glycolysis of macrophages in allergic asthma mice.
    Ji X, Nie C, Yao Y, Ma Y, Huang H, Hao C., Free PMC Article

    05/10/2024
    S100A9 exacerbates sepsis-induced acute lung injury via the IL17-NFkappaB-caspase-3 signaling pathway.

    S100A9 exacerbates sepsis-induced acute lung injury via the IL17-NFκB-caspase-3 signaling pathway.
    Pei H, Chen J, Qu J, Lu Z.

    04/25/2024
    MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells.

    MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells.
    Yang Y, Zhang X, Jing L, Xiao Y, Gao Y, Hu Y, Jia S, Zhou G, Xiong H, Dong G., Free PMC Article

    03/14/2024
    Deficiency of S100A8/A9 attenuates pulmonary microvascular leakage in septic mice.

    Deficiency of S100A8/A9 attenuates pulmonary microvascular leakage in septic mice.
    Yu J, Zhao B, Pi Q, Zhou G, Cheng Z, Qu C, Wang X, Kong L, Luo S, Du D, Guo Y., Free PMC Article

    03/14/2024
    S100A9[-/-] alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFkappaB signaling axis.

    S100A9(-/-) alleviates LPS-induced acute lung injury by regulating M1 macrophage polarization and inhibiting pyroptosis via the TLR4/MyD88/NFκB signaling axis.
    Gong C, Ma J, Deng Y, Liu Q, Zhan Z, Gan H, Xiang X, Zhang M, Cao K, Shen T, Fang L, Shen B, Shen S, Ding S.

    03/5/2024
    CD146 deficiency aggravates chronic obstructive pulmonary disease via the increased production of S100A9 and MMP-9 in macrophages.

    CD146 deficiency aggravates chronic obstructive pulmonary disease via the increased production of S100A9 and MMP-9 in macrophages.
    Jiang J, Wang M, Shen W, Wu J, Ma Q, Wang Z, Chen Z, Bian T, Ji N, Huang M, Zhang M.

    01/29/2024
    Effect of Proinflammatory S100A9 Protein on Migration and Proliferation of Microglial Cells.

    Effect of Proinflammatory S100A9 Protein on Migration and Proliferation of Microglial Cells.
    Bai Q, Sun D, Zeng Y, Zhu J, Zhang C, Zhang X, Chen L, Zhou X, Ye L, Tang Y, Liu Y, Morozova-Roche LA.

    01/5/2024
    Inhibition of S100A9 alleviates neurogenic pulmonary edema after subarachnoid hemorrhage.

    Inhibition of S100A9 alleviates neurogenic pulmonary edema after subarachnoid hemorrhage.
    Wang G, Hou G, Tian Q, Liu C, Guo Y, Wei H, Zhang Z, Li M.

    12/6/2023
    S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis.

    S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis.
    von Wulffen M, Luehrmann V, Robeck S, Russo A, Fischer-Riepe L, van den Bosch M, van Lent P, Loser K, Gabrilovich DI, Hermann S, Roth J, Vogl T.

    10/26/2023
    S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by beta1-adrenoceptor autoantibodies.

    S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β(1)-adrenoceptor autoantibodies.
    Zhi X, Shi S, Li Y, Ma M, Long Y, Li C, Hao H, Liu H, Wang X, Wang L., Free PMC Article

    09/28/2023
    A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis.

    A positive feedback cycle between the alarmin S100A8/A9 and NLRP3 inflammasome-GSDMD signalling reinforces the innate immune response in Candida albicans keratitis.
    Fang X, Lian H, Liu S, Dong J, Hua X, Li W, Liao C, Yuan X.

    09/6/2023
    S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.

    S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.
    Silva de Melo BM, Veras FP, Zwicky P, Lima D, Ingelfinger F, Martins TV, da Silva Prado D, Schärli S, Publio G, Hiroki CH, Melo PH, Saraiva A, Norbiato T, Lima L, Ryffel B, Vogl T, Roth J, Waisman A, Nakaya HI, da Silva Souza C, Cunha FQ, Cunha TM, Becher B, Alves-Filho JC.

    08/28/2023
    S100A9 Regulated M1/M2 Macrophage Polarization in Interleukin-10-Induced Promotion of Malignant Pleural Effusion.

    S100A9 Regulated M1/M2 Macrophage Polarization in Interleukin-10-Induced Promotion of Malignant Pleural Effusion.
    Pei XB, Yi FS, Dong SF, Chen QY, Shi XY., Free PMC Article

    08/4/2023
    S100A9 is indispensable for survival of pneumococcal pneumonia in mice.

    S100A9 is indispensable for survival of pneumococcal pneumonia in mice.
    Ostermann L, Seeliger B, David S, Flasche C, Maus R, Reinboth MS, Christmann M, Neumann K, Brand K, Seltmann S, Bühling F, Paton JC, Roth J, Vogl T, Viemann D, Welte T, Maus UA., Free PMC Article

    07/24/2023
    Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.

    Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
    Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J.

    07/24/2023
    Deficiency of S100 calcium binding protein A9 attenuates vascular dysfunction in aged mice.

    Deficiency of S100 calcium binding protein A9 attenuates vascular dysfunction in aged mice.
    Zhao B, Yu J, Luo Y, Xie M, Qu C, Shi Q, Wang X, Zhao X, Kong L, Zhao Y, Guo Y., Free PMC Article

    06/13/2023
    S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction.

    S100a8/a9 contributes to sepsis-induced cardiomyopathy by activating ERK1/2-Drp1-mediated mitochondrial fission and respiratory dysfunction.
    Wu F, Zhang YT, Teng F, Li HH, Guo SB.

    02/28/2023
    Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.

    Deficiency of S100A9 Alleviates Sepsis-Induced Acute Liver Injury through Regulating AKT-AMPK-Dependent Mitochondrial Energy Metabolism.
    Zhang Y, Wu F, Teng F, Guo S, Li H., Free PMC Article

    02/15/2023
    Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma.

    Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma.
    Argyris PP, Saavedra F, Malz C, Stone IA, Wei Y, Boyle WS, Johnstone KF, Khammanivong A, Herzberg MC., Free PMC Article

    02/4/2023
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