| Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells. | Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells.
Dennis M, Hurley A, Bray N, Cordero C, Ilagan J, Mertz TM, Roberts SA., Free PMC Article | 10/31/2024 |
| The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis. | The cytidine deaminase APOBEC3A regulates nucleolar function to promote cell growth and ribosome biogenesis.
McCool MA, Bryant CJ, Abriola L, Surovtseva YV, Baserga SJ., Free PMC Article | 08/16/2024 |
| The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. | The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress.
Fingerman DF, O'Leary DR, Hansen AR, Tran T, Harris BR, DeWeerd RA, Hayer KE, Fan J, Chen E, Tennakoon M, Meroni A, Szeto JH, Devenport J, LaVigne D, Weitzman MD, Shalem O, Bednarski J, Vindigni A, Zhao X, Green AM., Free PMC Article | 08/2/2024 |
| Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry. | Regulatory variants of APOBEC3 genes potentially associate with COVID-19 severity in populations with African ancestry.
Zhang K, Chen F, Shen HY, Zhang PP, Gao H, Peng H, Luo YS, Cheng ZS., Free PMC Article | 04/2/2024 |
| Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations. | Distinguishing preferences of human APOBEC3A and APOBEC3B for cytosines in hairpin loops, and reflection of these preferences in APOBEC-signature cancer genome mutations.
Butt Y, Sakhtemani R, Mohamad-Ramshan R, Lawrence MS, Bhagwat AS., Free PMC Article | 03/20/2024 |
| Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer. | Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.
Carpenter MA, Temiz NA, Ibrahim MA, Jarvis MC, Brown MR, Argyris PP, Brown WL, Starrett GJ, Yee D, Harris RS., Free PMC Article | 12/21/2023 |
| Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage. | Mitochondrial double-stranded RNA triggers induction of the antiviral DNA deaminase APOBEC3A and nuclear DNA damage.
Wick C, Moghadasi SA, Becker JT, Fanunza E, Oh S, Bournique E, Buisson R, Harris RS., Free PMC Article | 11/13/2023 |
| Unraveling the Enzyme-Substrate Properties for APOBEC3A-Mediated RNA Editing. | Unraveling the Enzyme-Substrate Properties for APOBEC3A-Mediated RNA Editing.
Kim K, Shi AB, Kelley K, Chen XS., Free PMC Article | 10/2/2023 |
| Therapy-induced APOBEC3A drives evolution of persistent cancer cells. | Therapy-induced APOBEC3A drives evolution of persistent cancer cells.
Isozaki H, Sakhtemani R, Abbasi A, Nikpour N, Stanzione M, Oh S, Langenbucher A, Monroe S, Su W, Cabanos HF, Siddiqui FM, Phan N, Jalili P, Timonina D, Bilton S, Gomez-Caraballo M, Archibald HL, Nangia V, Dionne K, Riley A, Lawlor M, Banwait MK, Cobb RG, Zou L, Dyson NJ, Ott CJ, Benes C, Getz G, Chan CS, Shaw AT, Gainor JF, Lin JJ, Sequist LV, Piotrowska Z, Yeap BY, Engelman JA, Lee JJ, Maruvka YE, Buisson R, Lawrence MS, Hata AN., Free PMC Article | 08/14/2023 |
| The role of APOBEC3A in cervical cancer development and progression: A retrospective study. | The role of APOBEC3A in cervical cancer development and progression: A retrospective study.
Zhang M, Wei Z, Zhao H, Zhang S, Wu J, Zhou J, Wang Y, Wang L, Du Y. | 07/17/2023 |
| Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression. | Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression.
Göttig L, Weiß C, Stubbe M, Hanrieder L, Hofmann S, Grodziecki A, Stadler D, Carpentier A, Protzer U, Schreiner S., Free PMC Article | 06/29/2023 |
| Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A. | Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A.
Kurup HM, Kvach MV, Harjes S, Jameson GB, Harjes E, Filichev VV., Free PMC Article | 06/28/2023 |
| DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo. | DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo.
Naumann JA, Argyris PP, Carpenter MA, Gupta HB, Chen Y, Temiz NA, Zhou Y, Durfee C, Proehl J, Koniar BL, Conticello SG, Largaespada DA, Brown WL, Aihara H, Vogel RI, Harris RS., Free PMC Article | 06/13/2023 |
| APOBEC3A/B deletion polymorphism and endometrial cancer risk. | APOBEC3A/B deletion polymorphism and endometrial cancer risk.
Sofiyeva N, Krakstad C, Halle MK, O'Mara TA, Romundstad P, Hveem K, Vatten L, Lønning PE, Gansmo LB, Knappskog S., Free PMC Article | 04/5/2023 |
| Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome. | Cellular APOBEC3A deaminase drives mutations in the SARS-CoV-2 genome.
Nakata Y, Ode H, Kubota M, Kasahara T, Matsuoka K, Sugimoto A, Imahashi M, Yokomaku Y, Iwatani Y., Free PMC Article | 02/4/2023 |
| Differences in integration frequencies and APOBEC3 profiles of five high-risk HPV types adheres to phylogeny. | Differences in integration frequencies and APOBEC3 profiles of five high-risk HPV types adheres to phylogeny.
Løvestad AH, Repesa A, Costanzi JM, Lagström S, Christiansen IK, Rounge TB, Ambur OH., Free PMC Article | 12/24/2022 |
| The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness. | The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness.
Kim K, Calabrese P, Wang S, Qin C, Rao Y, Feng P, Chen XS., Free PMC Article | 10/22/2022 |
| Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis. | Evaluation of APOBEC3 expression as prognostic marker in squamous cell carcinoma of the penis.
Trimmel B, Oszwald A, Diemand C, Ertl IE, Lemberger U, Bruchbacher A, Brettner R, Korn S, Resch I, Comperat E, Shariat SF, Hassler MR., Free PMC Article | 08/6/2022 |
| Mechanisms of APOBEC3 mutagenesis in human cancer cells. | Mechanisms of APOBEC3 mutagenesis in human cancer cells.
Petljak M, Dananberg A, Chu K, Bergstrom EN, Striepen J, von Morgen P, Chen Y, Shah H, Sale JE, Alexandrov LB, Stratton MR, Maciejowski J., Free PMC Article | 08/6/2022 |
| APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis. | APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis.
Revathidevi S, Nakaoka H, Suda K, Fujito N, Munirajan AK, Yoshihara K, Enomoto T, Inoue I. | 06/11/2022 |
| APOBEC3A regulates transcription from interferon-stimulated response elements. | APOBEC3A regulates transcription from interferon-stimulated response elements.
Taura M, Frank JA, Takahashi T, Kong Y, Kudo E, Song E, Tokuyama M, Iwasaki A., Free PMC Article | 05/21/2022 |
| The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity. | The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity.
Barka A, Berríos KN, Bailer P, Schutsky EK, Wang T, Kohli RM., Free PMC Article | 05/7/2022 |
| APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis. | APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis.
Wörmann SM, Zhang A, Thege FI, Cowan RW, Rupani DN, Wang R, Manning SL, Gates C, Wu W, Levin-Klein R, Rajapakshe KI, Yu M, Multani AS, Kang Y, Taniguchi CM, Schlacher K, Bellin MD, Katz MHG, Kim MP, Fleming JB, Gallinger S, Maddipati R, Harris RS, Notta F, Ross SR, Maitra A, Rhim AD. | 04/30/2022 |
| Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers. | Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers.
DeWeerd RA, Németh E, Póti Á, Petryk N, Chen CL, Hyrien O, Szüts D, Green AM., Free PMC Article | 04/23/2022 |
| Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer. | Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer.
Baker SC, Mason AS, Slip RG, Skinner KT, Macdonald A, Masood O, Harris RS, Fenton TR, Periyasamy M, Ali S, Southgate J., Free PMC Article | 04/23/2022 |