| Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation. | Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation.
Kesarwani M, Kincaid Z, Azhar M, Azam M., Free PMC Article | 09/30/2024 |
| CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck squamous cell carcinoma growth. | CCR7/DUSP1 signaling Axis mediates iCAF to regulates head and neck squamous cell carcinoma growth.
Gao J, Wang Z, Lin S, Tian Y, Wu H, Li Z, Liu F. | 08/31/2024 |
| Dual-specificity phosphatase 1 interacts with prohibitin 2 to improve mitochondrial quality control against type-3 cardiorenal syndrome. | Dual-specificity phosphatase 1 interacts with prohibitin 2 to improve mitochondrial quality control against type-3 cardiorenal syndrome.
Liu N, Ding Y, Zhou H, Chang X, Lou L., Free PMC Article | 03/12/2024 |
| MKP-1 regulates the inflammatory activation of microglia against Alzheimer's disease. | MKP-1 regulates the inflammatory activation of microglia against Alzheimer's disease.
Li J, Wang L, Zeng Q, He J, Tang Q, Wang K, He G., Free PMC Article | 03/4/2024 |
| Heat shock induces HuR-dependent MKP-1 posttranslational regulation through the p38 MAPK signaling cascade. | Heat shock induces HuR-dependent MKP-1 posttranslational regulation through the p38 MAPK signaling cascade.
Ma XJ, Sun Z, Wang YP, Yao XP, Luo TT, Bao YL, Ainiwaer D, Zhang T, Zhu H, Zhang Y, Hu FM, Yu WY. | 01/26/2024 |
| DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK. | DUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK.
Shi L, Zha H, Pan Z, Wang J, Xia Y, Li H, Huang H, Yue R, Song Z, Zhu J., Free PMC Article | 11/14/2023 |
| ANGPTL2 aggravates LPS-induced septic cardiomyopathy via NLRP3-mediated inflammasome in a DUSP1-dependent pathway. | ANGPTL2 aggravates LPS-induced septic cardiomyopathy via NLRP3-mediated inflammasome in a DUSP1-dependent pathway.
Li J, Wan T, Liu C, Liu H, Ke D, Li L. | 09/27/2023 |
| MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention. | MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention.
Qiu B, Lawan A, Xirouchaki CE, Yi JS, Robert M, Zhang L, Brown W, Fernández-Hernando C, Yang X, Tiganis T, Bennett AM., Free PMC Article | 09/11/2023 |
| DUSP1 interacts with and dephosphorylates VCP to improve mitochondrial quality control against endotoxemia-induced myocardial dysfunction. | DUSP1 interacts with and dephosphorylates VCP to improve mitochondrial quality control against endotoxemia-induced myocardial dysfunction.
Zhu H, Wang J, Xin T, Chen S, Hu R, Li Y, Zhang M, Zhou H., Free PMC Article | 07/25/2023 |
| p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis. | p38 MAPK and MKP-1 control the glycolytic program via the bifunctional glycolysis regulator PFKFB3 during sepsis.
Mager CE, Mormol JM, Shelton ED, Murphy PR, Bowman BA, Barley TJ, Wang X, Linn SC, Liu K, Nelin LD, Hafner M, Liu Y., Free PMC Article | 05/17/2023 |
| The Ninj1/Dusp1 Axis Contributes to Liver Ischemia Reperfusion Injury by Regulating Macrophage Activation and Neutrophil Infiltration. | The Ninj1/Dusp1 Axis Contributes to Liver Ischemia Reperfusion Injury by Regulating Macrophage Activation and Neutrophil Infiltration.
Hu Y, Zhan F, Wang Y, Wang D, Lu H, Wu C, Xia Y, Meng L, Zhang F, Wang X, Zhou S., Free PMC Article | 04/24/2023 |
| MKP-1 Deficiency Exacerbates Skin Fibrosis in a Mouse Model of Scleroderma. | MKP-1 Deficiency Exacerbates Skin Fibrosis in a Mouse Model of Scleroderma.
Scotece M, Hämäläinen M, Leppänen T, Vuolteenaho K, Moilanen E., Free PMC Article | 04/12/2023 |
| SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis. | SNHG1 alleviates the oxidative stress and inflammatory response in traumatic brain injury through regulating miR-377-3p/DUSP1 axis.
Jiao W, Jiang L, Zhang Y. | 01/11/2023 |
| Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism. | Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism.
Tan Y, Zhang Y, He J, Wu F, Wu D, Shi N, Liu W, Li Z, Liu W, Zhou H, Chen W., Free PMC Article | 09/24/2022 |
| Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection. | Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection.
Barley TJ, Murphy PR, Wang X, Bowman BA, Mormol JM, Mager CE, Kirk SG, Cash CJ, Linn SC, Meng X, Nelin LD, Chen B, Hafner M, Zhang J, Liu Y., Free PMC Article | 06/11/2022 |
| MKP-1 modulates ubiquitination/phosphorylation of TLR signaling. | MKP-1 modulates ubiquitination/phosphorylation of TLR signaling.
Talreja J, Bauerfeld C, Wang X, Hafner M, Liu Y, Samavati L., Free PMC Article | 03/26/2022 |
| M1 macrophage-derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA-98/DUSP1/JNK axis. | M1 macrophage-derived exosomes aggravate bone loss in postmenopausal osteoporosis via a microRNA-98/DUSP1/JNK axis.
Yu L, Hu M, Cui X, Bao D, Luo Z, Li D, Li L, Liu N, Wu Y, Luo X, Ma Y. | 03/5/2022 |
| The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy. | The MAP Kinase Phosphatase MKP-1 Modulates Neurogenesis via Effects on BNIP3 and Autophagy.
Li Y, Halterman MW., Free PMC Article | 01/22/2022 |
| Knockout of MAPK Phosphatase-1 Exaggerates Type I IFN Response during Systemic Escherichia coli Infection. | Knockout of MAPK Phosphatase-1 Exaggerates Type I IFN Response during Systemic Escherichia coli Infection.
Kirk SG, Murphy PR, Wang X, Cash CJ, Barley TJ, Bowman BA, Batty AJ, Ackerman WE 4th, Zhang J, Nelin LD, Hafner M, Liu Y., Free PMC Article | 01/8/2022 |
| Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation. | Early p38 Activation Regulated by MKP-1 Is Determinant for High Levels of IL-10 Expression Through TLR2 Activation.
Francisco S, Arranz A, Merino J, Punzón C, Perona R, Fresno M., Free PMC Article | 10/23/2021 |
| Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice. | Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice.
Hammad A, Zheng ZH, Namani A, Elshaer M, Wang XJ, Tang X., Free PMC Article | 10/23/2021 |
| MKP-1 Modulates Mitochondrial Transcription Factors, Oxidative Phosphorylation, and Glycolysis. | MKP-1 Modulates Mitochondrial Transcription Factors, Oxidative Phosphorylation, and Glycolysis.
Bauerfeld C, Talwar H, Zhang K, Liu Y, Samavati L., Free PMC Article | 08/7/2021 |
| AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1. | AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1.
Jiao F, Wang Y, Zhang W, Zhang H, Chen Q, Wang L, Shi C, Gong Z. | 05/29/2021 |
| MKP1 in the medial prefrontal cortex modulates chronic neuropathic pain via regulation of p38 and JNK1/2. | MKP1 in the medial prefrontal cortex modulates chronic neuropathic pain via regulation of p38 and JNK1/2.
Qian Y, Wang Z, Zhou S, Zhao W, Yin C, Cao J, Wang Z, Li Y. | 04/3/2021 |
| Inhibition of PTP1B Promotes M2 Polarization via MicroRNA-26a/MKP1 Signaling Pathway in Murine Macrophages. | Inhibition of PTP1B Promotes M2 Polarization via MicroRNA-26a/MKP1 Signaling Pathway in Murine Macrophages.
Xu X, Wang X, Guo Y, Bai Y, He S, Wang N, Lin Y, Fisher M, Liu Q, Yao Y., Free PMC Article | 10/10/2020 |