| Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice. | Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin-deficient mice.
Krzistetzko J, Géraud C, Dormann C, Riedel A, Leibing T., Free PMC Article | 10/28/2024 |
| Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice. | Deficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.
Leibing T, Riedel A, Xi Y, Adrian M, Krzistetzko J, Kirkamm C, Dormann C, Schledzewski K, Goerdt S, Géraud C., Free PMC Article | 09/15/2023 |
| Stabilin-1 plays a protective role against Listeria monocytogenes infection through the regulation of cytokine and chemokine production and immune cell recruitment. | Stabilin-1 plays a protective role against Listeria monocytogenes infection through the regulation of cytokine and chemokine production and immune cell recruitment.
Pombinho R, Pinheiro J, Resende M, Meireles D, Jalkanen S, Sousa S, Cabanes D., Free PMC Article | 01/29/2022 |
| Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1. | Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1.
Tadayon S, Dunkel J, Takeda A, Eichin D, Virtakoivu R, Elima K, Jalkanen S, Hollmén M., Free PMC Article | 06/26/2021 |
| New tools to prevent cancer growth and spread: a 'Clever' approach. | New tools to prevent cancer growth and spread: a 'Clever' approach.
Hollmén M, Figueiredo CR, Jalkanen S., Free PMC Article | 02/27/2021 |
| Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study. | Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study.
Kim SY, Lee EH, Kim EN, Son WC, Kim YH, Park SY, Kim IS, Kim JE., Free PMC Article | 02/27/2021 |
| Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells. | Exploring the transcriptomic network of multi-ligand scavenger receptor Stabilin-1- and Stabilin-2-deficient liver sinusoidal endothelial cells.
Olsavszky V, Sticht C, Schmid CD, Winkler M, Wohlfeil SA, Olsavszky A, Schledzewski K, Géraud C, Goerdt S, Leibing T, Koch PS. | 02/2/2021 |
| Ablation of Stabilin-1 Enhances Bone-Resorbing Activity in Osteoclasts In Vitro. | Ablation of Stabilin-1 Enhances Bone-Resorbing Activity in Osteoclasts In Vitro.
Kim SY, Lee EH, Park SY, Choi H, Koh JT, Park EK, Kim IS, Kim JE. | 10/3/2020 |
| Bone marrow-specific Stabilin-1 deletion does not affect the susceptibility for atherosclerosis in Ldl receptor knockout mice. | Hematopoietic Stabilin-1 deficiency does not influence atherosclerosis susceptibility in LDL receptor knockout mice.
Nahon JE, Hoekstra M, van Hulst S, Manta C, Goerdt S, Geerling JJ, Géraud C, Van Eck M. | 04/18/2020 |
| Data show that the excessive inflammatory activity of monocytes/macrophages in the absence of Clever-1/Stabilin-1 results in augmented humoral immune responses in vivo. | Enhanced Antibody Production in Clever-1/Stabilin-1-Deficient Mice.
Dunkel J, Viitala M, Karikoski M, Rantakari P, Virtakoivu R, Elima K, Hollmén M, Jalkanen S, Salmi M., Free PMC Article | 10/5/2019 |
| these findings indicated that STAB-1 regulated and maintained vascular integrity through the clearance of infected apoptotic endothelial cells | Macrophagic Stabilin-1 Restored Disruption of Vascular Integrity Caused by Sepsis.
Lee W, Park SY, Yoo Y, Kim SY, Kim JE, Kim SW, Seo YK, Park EK, Kim IS, Bae JS. | 01/19/2019 |
| this study demonstrated the important role of macrophage STAB-1 in protecting against vascular barrier dysfunction in sepsis | Stabilin-1-Mediated Efferocytosis Protects against Vascular Leakage in Sepsis: A Novel Therapeutic Approach?
Mirtschink P, Chavakis T. | 01/12/2019 |
| Data show that stabilin-1 and stabilin-2 differentially expressed in isolated pancreatic Islets. | Scavenging Endothelium of Pancreatic Islets: Differential Expression of Stabilin-1 and Stabilin-2 in Mice and Humans.
Sandberg M, Johansson S, Sagulin L, Jansson L, Johansson S. | 06/16/2018 |
| Results suggest stabilin-1 mediated silent clearance of extracellular tumor growth-inhibiting factors as a mechanism of stabilin-1 induced tumor growth. | Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model.
Riabov V, Yin S, Song B, Avdic A, Schledzewski K, Ovsiy I, Gratchev A, Llopis Verdiell M, Sticht C, Schmuttermaier C, Schönhaber H, Weiss C, Fields AP, Simon-Keller K, Pfister F, Berlit S, Marx A, Arnold B, Goerdt S, Kzhyshkowska J., Free PMC Article | 01/20/2018 |
| This work identifies Clever-1 in type II macrophages and in tumor vasculature as a new immunosuppressive molecule in cancer. | Clever-1/stabilin-1 controls cancer growth and metastasis.
Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmén M, Kelkka T, Gerke H, Huovinen V, Irjala H, Holmdahl R, Salmi M, Jalkanen S. | 11/21/2015 |
| We investigated stabilin-1 expressing immune cells in the tumor environment and showed a transient population of alternatively activated macrophages expressing it in the tumor environment and the disappearance of that population as the tumor progresses. | Stabilin-1 expression in tumor associated macrophages.
David C, Nance JP, Hubbard J, Hsu M, Binder D, Wilson EH., Free PMC Article | 03/9/2013 |
| a low pH microenvironment up-regulates stabilin-1 expression in macrophage | Extracellular low pH modulates phosphatidylserine-dependent phagocytosis in macrophages by increasing stabilin-1 expression.
Park SY, Bae DJ, Kim MJ, Piao ML, Kim IS., Free PMC Article | 09/22/2012 |
| we show that stabilin-1 and stabilin-2 in hepatic sinusoidal endothelial cells (HSECs) are critical in effectively clearing damaged RBCs in mouse liver | Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.
Lee SJ, Park SY, Jung MY, Bae SM, Kim IS. | 07/16/2011 |
| Data suggest that stabilin-1 and -2 together guarantee proper hepatic clearance of potentially noxious agents in the blood and maintain tissue homeostasis not only in the liver but also distant organs. | Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.
Schledzewski K, Géraud C, Arnold B, Wang S, Gröne HJ, Kempf T, Wollert KC, Straub BK, Schirmacher P, Demory A, Schönhaber H, Gratchev A, Dietz L, Thierse HJ, Kzhyshkowska J, Goerdt S., Free PMC Article | 04/2/2011 |
| Results indicate that anti-Clever-1/Stabilin-1 treatment can target two different arms of the vasculature--traffic via lymphatics and inflamed blood vessels. | Clever-1/Stabilin-1 regulates lymphocyte migration within lymphatics and leukocyte entrance to sites of inflammation.
Karikoski M, Irjala H, Maksimow M, Miiluniemi M, Granfors K, Hernesniemi S, Elima K, Moldenhauer G, Schledzewski K, Kzhyshkowska J, Goerdt S, Salmi M, Jalkanen S. | 01/21/2010 |
| analysis of mouse fasciclin-containing genes (betaigH3, periostin, stabilin-1, and stabilin-2) expression patterns during valvuloseptal morphogenesis | Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis.
Lindsley A, Li W, Wang J, Maeda N, Rogers R, Conway SJ. | 01/21/2010 |