| Skeletal muscle-enriched miRNAs are highly unstable in vivo and may be regulated in a Dicer-independent manner. | Skeletal muscle-enriched miRNAs are highly unstable in vivo and may be regulated in a Dicer-independent manner.
Oikawa S, Yuan S, Kato Y, Akimoto T. | 04/18/2024 |
| Biallelic Dicer1 Mutations in the Gynecologic Tract of Mice Drive Lineage-Specific Development of DICER1 Syndrome-Associated Cancer. | Biallelic Dicer1 Mutations in the Gynecologic Tract of Mice Drive Lineage-Specific Development of DICER1 Syndrome-Associated Cancer.
Wang Y, Chen SY, Ta M, Senz J, Tao LV, Thornton S, Tamvada N, Yang W, Moscovitz Y, Li E, Guo J, Shen C, Douglas JM, Ei-Naggar AM, Kommoss FKF, Underhill TM, Singh N, Gilks CB, Morin GB, Huntsman DG. | 11/3/2023 |
| Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas. | Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas.
Reyes-Castro RA, Chen SY, Seemann J, Kundu ST, Gibbons DL, Arur S., Free PMC Article | 09/8/2023 |
| AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1-Dicer-1-mir-122 hierarchy. | AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1-Dicer-1-mir-122 hierarchy.
Das O, Kundu J, Ghosh A, Gautam A, Ghosh S, Chakraborty M, Masid A, Gauri SS, Mitra D, Dutta M, Mukherjee B, Sinha S, Bhaumik M., Free PMC Article | 01/14/2023 |
| STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals. | STUB1 regulates antiviral RNAi through inducing ubiquitination and degradation of Dicer and AGO2 in mammals.
Zhang S, Zhang X, Bie Y, Kong J, Wang A, Qiu Y, Zhou X., Free PMC Article | 09/3/2022 |
| Dicer deletion in hepatocytes promotes macrophages M1 polarization through dysregulated miR-192-3p/IGF2 in non-alcoholic steatohepatitis and hepatocellular carcinoma. | Dicer deletion in hepatocytes promotes macrophages M1 polarization through dysregulated miR-192-3p/IGF2 in non-alcoholic steatohepatitis and hepatocellular carcinoma.
Hu C, Li X, Sui Y, Chen Y, Zhao Y, Yang Y, Zhou Q, Ni H, Sun L, Gan W, Li J, Liu Y. | 08/27/2022 |
| Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice. | Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M., Free PMC Article | 08/20/2022 |
| Amyloid peptide exerts a rapid induction of Dicer1 protein in neuron via reducing phosphorylation. | Amyloid peptide exerts a rapid induction of Dicer1 protein in neuron via reducing phosphorylation.
Wang Y, Xiu X, Wu S. | 03/19/2022 |
| ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P. | ADAR1 inhibits adipogenesis and obesity by interacting with Dicer to promote the maturation of miR-155-5P.
Yu Z, Luo R, Li Y, Li X, Yang Z, Peng J, Huang K. | 03/12/2022 |
| FMRP and MOV10 regulate Dicer1 expression and dendrite development. | FMRP and MOV10 regulate Dicer1 expression and dendrite development.
Lannom MC, Nielsen J, Nawaz A, Shilikbay T, Ceman S., Free PMC Article | 01/22/2022 |
| Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and Abeta(1-42) in female 3xTg-AD mice. | Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and Aβ(1-42) in female 3xTg-AD mice.
Dungan CM, Valentino T, Vechetti IJ Jr, Zdunek CJ, Murphy MP, Lin AL, McCarthy JJ, Peterson CA., Free PMC Article | 10/9/2021 |
| Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells. | Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells.
Gurung C, Fendereski M, Sapkota K, Guo J, Huang F, Guo YL., Free PMC Article | 08/28/2021 |
| Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma. | Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma.
Anslow MJ, Bodnar AJ, Cerqueira DM, Bushnell D, Shrom BE, Sims-Lucas S, Bates CM, Ho J., Free PMC Article | 08/28/2021 |
| Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination. | Dicer Deletion in Astrocytes Inhibits Oligodendroglial Differentiation and Myelination.
Liu K, Yu B, Chen JF, Li RX, Chen L, Ren SY, Wang F, Mei F, Xiao L., Free PMC Article | 08/21/2021 |
| Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis. | Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis.
Wu X, Chen X, Liu H, He ZW, Wang Z, Wei LJ, Wang WY, Zhong S, He Q, Zhang Z, Ou R, Gao J, Lei Y, Yang W, Song G, Jin Y, Zhou L, Xu Y, Tang KF., Free PMC Article | 08/7/2021 |
| An isoform of Dicer protects mammalian stem cells against multiple RNA viruses. | An isoform of Dicer protects mammalian stem cells against multiple RNA viruses.
Poirier EZ, Buck MD, Chakravarty P, Carvalho J, Frederico B, Cardoso A, Healy L, Ulferts R, Beale R, Reis e Sousa C., Free PMC Article | 07/24/2021 |
| Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Abeta42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2. | Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.
Wang Y, Lian M, Zhou J, Wu S. | 07/3/2021 |
| Hypoxia-induced apoptosis of astrocytes is mediated by reduction of Dicer and activation of caspase-1. | Hypoxia-induced apoptosis of astrocytes is mediated by reduction of Dicer and activation of caspase-1.
Kang YW, Kim YS, Park JY, Chu GE, Yang YC, Choi BY, Cho WG. | 01/16/2021 |
| Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma. | Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
Wang X, Wendel JRH, Emerson RE, Broaddus RR, Creighton CJ, Rusch DB, Buechlein A, DeMayo FJ, Lydon JP, Hawkins SM., Free PMC Article | 12/12/2020 |
| Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise. | Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise.
Brandão BB, Madsen S, Rabiee A, Oliverio M, Ruiz GP, Ferrucci DL, Branquinho JL, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Martins AS, Guerra BA, Knittel TL, Søgaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA., Free PMC Article | 11/21/2020 |
| DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis. | DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis.
Yadav RP, Mäkelä JA, Hyssälä H, Cisneros-Montalvo S, Kotaja N., Free PMC Article | 09/26/2020 |
| Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. | Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision.
Aldunate EZ, Di Foggia V, Di Marco F, Hervas LA, Ribeiro JC, Holder DL, Patel A, Jannini TB, Thompson DA, Martinez-Barbera JP, Pearson RA, Ali RR, Sowden JC., Free PMC Article | 09/19/2020 |
| Deficiency of dicer1 induces spontaneous retinal pigmented epithelium atrophy and choroidal and retinal neovascularization in mouse models. | Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, Georgel P, Hatada I, Chang B, Kerur N, Ambati BK, Ambati J, Gelfand BD., Free PMC Article | 06/20/2020 |
| After cardiotoxin injection, the Dicer knocked out mice showed impaired muscle regeneration. | Conditional Deletion of Dicer in Adult Mice Impairs Skeletal Muscle Regeneration.
Oikawa S, Lee M, Akimoto T., Free PMC Article | 04/18/2020 |
| Dicer gene deletion induced a metabolic shift from oxidative metabolism to aerobic glycolysis in Cardiac mesenchymal stem cells (C-MSC), suggesting that Dicer functions as a metabolic switch in C-MSC, which in turn may regulate proliferation and environmental adaptation. | RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells.
Su X, Jin Y, Shen Y, Kim IM, Weintraub NL, Tang Y., Free PMC Article | 03/28/2020 |