U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    EEF1A1 eukaryotic translation elongation factor 1 alpha 1 [ Homo sapiens (human) ]

    Gene ID: 1915, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1.

    N-Acetylcysteine Inhibits Coxsackievirus B3 Replication by Downregulating Eukaryotic Translation Elongation Factor 1 Alpha 1.
    Wang Y, Luan T, Wang L, Feng D, Dong Y, Li S, Yang H, Chen Y, Fei Y, Lin L, Pan J, Zhong Z, Zhao W., Free PMC Article

    10/7/2024
    UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination.

    UCHL3 promotes hepatocellular carcinoma progression by stabilizing EEF1A1 through deubiquitination.
    Zhao J, Huo Q, Zhang J, Sun K, Guo J, Cheng F, Hu X, Xu Q., Free PMC Article

    07/26/2024
    Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells.

    Elongation factor 1A1 regulates metabolic substrate preference in mammalian cells.
    Wilson RB, Kozlov AM, Hatam Tehrani H, Twumasi-Ankrah JS, Chen YJ, Borrelli MJ, Sawyez CG, Maini S, Shepherd TG, Cumming RC, Betts DH, Borradaile NM., Free PMC Article

    04/4/2024
    Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation.

    Methylation of elongation factor 1A by yeast Efm4 or human eEF1A-KMT2 involves a beta-hairpin recognition motif and crosstalks with phosphorylation.
    Hamey JJ, Nguyen A, Haddad M, Vázquez-Campos X, Pfeiffer PG, Wilkins MR., Free PMC Article

    02/26/2024
    Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis.

    Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis.
    Minoia M, Quintana-Cordero J, Jetzinger K, Kotan IE, Turnbull KJ, Ciccarelli M, Masser AE, Liebers D, Gouarin E, Czech M, Hauryliuk V, Bukau B, Kramer G, Andréasson C., Free PMC Article

    02/23/2024
    Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.

    Understanding functions of eEF1 translation elongation factors beyond translation. A proteomic approach.
    Negrutskii BS, Porubleva LV, Malinowska A, Novosylna OV, Dadlez M, Knudsen CR.

    01/17/2024
    RNA-dependent RNA polymerase of SARS-CoV-2 regulate host mRNA translation efficiency by hijacking eEF1A factors.

    RNA-dependent RNA polymerase of SARS-CoV-2 regulate host mRNA translation efficiency by hijacking eEF1A factors.
    Gan H, Zhou X, Lei Q, Wu L, Niu J, Zheng Q.

    11/16/2023
    Dynamic regulation of eEF1A1 acetylation affects colorectal carcinogenesis.

    Dynamic regulation of eEF1A1 acetylation affects colorectal carcinogenesis.
    Jiang H, Zhang Y, Liu B, Yang X, Wang Z, Han M, Li H, Luo J, Yao H.

    08/25/2023
    Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis.

    Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1-EEF1A1 Axis.
    Li M, Yang L, Chan AKN, Pokharel SP, Liu Q, Mattson N, Xu X, Chang WH, Miyashita K, Singh P, Zhang L, Li M, Wu J, Wang J, Chen B, Chan LN, Lee J, Zhang XH, Rosen ST, Müschen M, Qi J, Chen J, Hiom K, Bishop AJR, Chen CW., Free PMC Article

    06/15/2023
    eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients.

    eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients.
    Fan AH, Zhao X, Liu H, Li D, Guo T, Zhang J, Duan L, Cheng H, Nie Y, Fan D, Zhao X, Lu Y., Free PMC Article

    01/28/2023
    Potential association of eEF1A dimethylation at lysine 55 in the basal area of Helicobacter pylori-eradicated gastric mucosa with the risk of gastric cancer: a retrospective observational study.

    Potential association of eEF1A dimethylation at lysine 55 in the basal area of Helicobacter pylori-eradicated gastric mucosa with the risk of gastric cancer: a retrospective observational study.
    Hirashita Y, Fukuda M, Kodama M, Tsukamoto Y, Okimoto T, Mizukami K, Kawahara Y, Wada Y, Ozaka S, Togo K, Kinoshita K, Fuchino T, Fukuda K, Okamoto K, Ogawa R, Matsunari O, Honda K, Murakami K., Free PMC Article

    01/28/2023
    Probe Synthesis Reveals Eukaryotic Translation Elongation Factor 1 Alpha 1 as the Anti-Pancreatic Cancer Target of BE-43547A2.

    Probe Synthesis Reveals Eukaryotic Translation Elongation Factor 1 Alpha 1 as the Anti-Pancreatic Cancer Target of BE-43547A(2).
    Liu C, Wang L, Sun Y, Zhao X, Chen T, Su X, Guo H, Wang Q, Xi X, Ding Y, Chen Y.

    09/10/2022
    Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.

    Analysis of the Expression and Subcellular Distribution of eEF1A1 and eEF1A2 mRNAs during Neurodevelopment.
    Wefers Z, Alecki C, Huang R, Jacob-Tomas S, Vera M., Free PMC Article

    07/2/2022
    HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells via eEF1A1-repressed SMAD4 transactivation.

    HNF4A-AS1-encoded small peptide promotes self-renewal and aggressiveness of neuroblastoma stem cells via eEF1A1-repressed SMAD4 transactivation.
    Song H, Wang J, Wang X, Yuan B, Li D, Hu A, Guo Y, Cai S, Jin S, Zhou Y, Li Q, Chen G, Gao H, Zheng L, Tong Q.

    05/7/2022
    TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation.

    TBP, PPIA, YWHAZ and EF1A1 Are the Most Stably Expressed Genes during Osteogenic Differentiation.
    Franko N, Vrščaj LA, Zore T, Ostanek B, Marc J, Lojk J., Free PMC Article

    04/30/2022
    High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1-actin Complex as a New Potential Target for Therapy.

    High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1-actin Complex as a New Potential Target for Therapy.
    Bosutti A, Dapas B, Grassi G, Bussani R, Zanconati F, Giudici F, Bottin C, Pavan N, Trombetta C, Scaggiante B., Free PMC Article

    04/30/2022
    A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2'3'-cGAMP.

    A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2'3'-cGAMP.
    Hou Y, Lu H, Li J, Guan Z, Zhang J, Zhang W, Yin C, Sun L, Zhang Y, Jiang H.

    03/5/2022
    A three-gene signature and clinical outcome in pediatric acute myeloid leukemia.

    A three-gene signature and clinical outcome in pediatric acute myeloid leukemia.
    Cai Z, Wu Y, Zhang F, Wu H.

    09/18/2021
    CircRNA_0050463 promotes influenza A virus replication by sponging miR-33b-5p to regulate EEF1A1.

    CircRNA_0050463 promotes influenza A virus replication by sponging miR-33b-5p to regulate EEF1A1.
    Shi N, Zhang S, Guo Y, Yu X, Zhao W, Zhang M, Guan Z, Duan M.

    09/4/2021
    Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.

    Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
    Qin S, Ye L, Zheng Y, Gao J.

    07/31/2021
    Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis.

    Identification of proteins involved in transcription/translation (eEF 1A1) as an inhibitor of Bax induced apoptosis.
    Akintade DD, Chaudhuri B., Free PMC Article

    06/5/2021
    Cryptosporidium parvum Elongation Factor 1alpha Participates in the Formation of Base Structure at the Infection Site During Invasion.

    Cryptosporidium parvum Elongation Factor 1α Participates in the Formation of Base Structure at the Infection Site During Invasion.
    Yu X, Guo F, Mouneimne RB, Zhu G., Free PMC Article

    04/3/2021
    Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.

    Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia.
    Xiao S, Wang Y, Ma Y, Liu J, Tang C, Deng A, Fang C., Free PMC Article

    11/21/2020
    Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells.

    Effects of eEF1A1 targeting by aptamer/siRNA in chronic lymphocytic leukaemia cells.
    Dapas B, Pozzato G, Zorzet S, Capolla S, Macor P, Scaggiante B, Coan M, Guerra C, Gnan C, Gattei V, Zanconati F, Grassi G.

    10/10/2020
    Fatty acylCoA synthetase FadD13 regulates proinflammatory cytokine secretion dependent on the NF-kappaB signalling pathway by binding to eEF1A1.

    Fatty acylCoA synthetase FadD13 regulates proinflammatory cytokine secretion dependent on the NF-κB signalling pathway by binding to eEF1A1.
    Wei S, Wang D, Li H, Bi L, Deng J, Zhu G, Zhang J, Li C, Li M, Fang Y, Zhang G, Chen J, Tao S, Zhang XE., Free PMC Article

    09/19/2020
    firstprevious page of 5 nextlast