Autophagy cooperates with PDGFRA to support oncogenic growth signaling.
Simpson JE, Gammoh N., Free PMC Article

PDGFRα(+)ITGA11(+) fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay.
Zheng H, An M, Luo Y, Diao X, Zhong W, Pang M, Lin Y, Chen J, Li Y, Kong Y, Zhao Y, Yin Y, Ai L, Huang J, Chen C, Lin T.

Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling.
Simpson JE, Muir MT, Lee M, Naughton C, Gilbert N, Pollard SM, Gammoh N.

Myeloid Cell-Specific Deletion of PDGFR-α Promotes Dysbiotic Intestinal Microbiota and thus Increased Colitis Susceptibility.
Dörk R, Pelczar P, Shiri AM, Volmari A, Zierz E, Giannou A, Böttcher M, Bosurgi L, Huber S, Manthey CF.

ADAMTS4 Enhances Oligodendrocyte Differentiation and Remyelination by Cleaving NG2 Proteoglycan and Attenuating PDGFRα Signaling.
Jiang C, Qiu W, Yang Y, Huang H, Dai ZM, Yang A, Tang T, Zhao X, Qiu M., Free PMC Article

PDGF receptor signal mediates the contribution of Nestin-positive cell lineage to subcutaneous fat development.
Takashima Y, Yamamoto S, Okuno N, Hamashima T, Dang ST, Tran ND, Okita N, Miwa F, Dang TC, Matsuo M, Takao K, Fujimori T, Mori H, Tobe K, Noguchi M, Sasahara M.

Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing.
Yao L, Rathnakar BH, Kwon HR, Sakashita H, Kim JH, Rackley A, Tomasek JJ, Berry WL, Olson LE., Free PMC Article

Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development.
Gillnäs S, Gallini R, He L, Betsholtz C, Andrae J., Free PMC Article

PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms.
Jacob JM, Di Carlo SE, Stzepourginski I, Lepelletier A, Ndiaye PD, Varet H, Legendre R, Kornobis E, Benabid A, Nigro G, Peduto L.

Platelet-Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension.
Solinc J, Raimbault-Machado J, Dierick F, El Bernoussi L, Tu L, Thuillet R, Mougenot N, Hoareau-Coudert B, Monceau V, Pavoine C, Atassi F, Sassoon D, Marazzi G, Harvey RP, Schofield P, Christ D, Humbert M, Guignabert C, Soubrier F, Nadaud S., Free PMC Article

PDGF-AA promotes cell-to-cell communication in osteocytes through PI3K/Akt signaling pathway.
Liu Y, Duan M, Guo D, Kan S, Zhang L, Aili M, Zhang D, Du W, Xie J.

PDGFRα-lineage origin directs monocytes to trafficking proficiency to support peripheral immunity.
Li YT, Yamazaki S, Takaki E, Ouchi Y, Kitayama T, Tamai K., Free PMC Article

Sprouty1 regulates gonadal white adipose tissue growth through a PDGFRα/β-Akt pathway.
Yang X, Pande S, Koza RA, Friesel R., Free PMC Article

Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination.
Cardona HJ, Somasundaram A, Crabtree DM, Gadd SL, Becher OJ., Free PMC Article

Molecular and functional characterization of detrusor PDGFRα positive cells in spinal cord injury-induced detrusor overactivity.
Lee K, Park SO, Choi PC, Ryoo SB, Lee H, Peri LE, Zhou T, Corrigan RD, Yanez AC, Moon SB, Perrino BA, Sanders KM, Koh SD., Free PMC Article

Identification of PDGFRα-positive interstitial cells in the distal segment of the murine vas deferens.
Hiroshige T, Uemura KI, Hirashima S, Hino K, Togo A, Ohta K, Igawa T, Nakamura KI., Free PMC Article

Vascular PDGFR-alpha protects against BBB dysfunction after stroke in mice.
Nguyen QL, Okuno N, Hamashima T, Dang ST, Fujikawa M, Ishii Y, Enomoto A, Maki T, Nguyen HN, Nguyen VT, Fujimori T, Mori H, Andrae J, Betsholtz C, Takao K, Yamamoto S, Sasahara M.

Autophagy inhibition blunts PDGFRA adipose progenitors' cell-autonomous fibrogenic response to high-fat diet.
Marcelin G, Da Cunha C, Gamblin C, Suffee N, Rouault C, Leclerc A, Lacombe A, Sokolovska N, Gautier EL, Clément K, Dugail I., Free PMC Article

Critical role of platelet-derived growth factor-α in angiogenesis after indirect bypass in a murine moyamoya disease model.
Hayashi T, Yamamoto S, Hamashima T, Mori H, Sasahara M, Kuroda S.

PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease.
Song K, Qing Y, Guo Q, Peden EK, Chen C, Mitch WE, Truong L, Cheng J., Free PMC Article

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.
Chen CCL, Deshmukh S, Jessa S, Hadjadj D, Lisi V, Andrade AF, Faury D, Jawhar W, Dali R, Suzuki H, Pathania M, A D, Dubois F, Woodward E, Hébert S, Coutelier M, Karamchandani J, Albrecht S, Brandner S, De Jay N, Gayden T, Bajic A, Harutyunyan AS, Marchione DM, Mikael LG, Juretic N, Zeinieh M, Russo C, Maestro N, Bassenden AV, Hauser P, Virga J, Bognar L, Klekner A, Zapotocky M, Vicha A, Krskova L, Vanova K, Zamecnik J, Sumerauer D, Ekert PG, Ziegler DS, Ellezam B, Filbin MG, Blanchette M, Hansford JR, Khuong-Quang DA, Berghuis AM, Weil AG, Garcia BA, Garzia L, Mack SC, Beroukhim R, Ligon KL, Taylor MD, Bandopadhayay P, Kramm C, Pfister SM, Korshunov A, Sturm D, Jones DTW, Salomoni P, Kleinman CL, Jabado N., Free PMC Article

Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor.
Sherafat A, Pfeiffer F, Reiss AM, Wood WM, Nishiyama A., Free PMC Article

Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha.
Kadrmas JL, Beckerle MC, Yoshigi M., Free PMC Article

Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis.
Sun C, Sakashita H, Kim J, Tang Z, Upchurch GM, Yao L, Berry WL, Griffin TM, Olson LE., Free PMC Article

PDGF Receptor Alpha Signaling Is Key for Müller Cell Homeostasis Functions.
Díaz-Lezama N, Wolf A, Koch S, Pfaller AM, Biber J, Guillonneau X, Langmann T, Grosche A., Free PMC Article