| Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic Subunit Beta Activation. | Dual-Specificity Phosphatase 4 Promotes Malignant Features in Colorectal Cancer Through Cyclic-AMP Response Element Binding Protein/Protein Kinase CAMP-Activated Catalytic Subunit Beta Activation.
Pei W, Yin W, Yu T, Zhang X, Zhang Q, Yang X, Shi C, Shen W, Liu G. | 10/3/2024 |
| Dual specific phosphatase 4 suppresses ferroptosis and enhances sorafenib resistance in hepatocellular carcinoma. | Dual specific phosphatase 4 suppresses ferroptosis and enhances sorafenib resistance in hepatocellular carcinoma.
Hao SH, Ma XD, Xu L, Xie JD, Feng ZH, Chen JW, Chen RX, Wang FW, Tang YH, Xie D, Cai MY. | 08/7/2024 |
| DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy. | DUSP4 maintains the survival and LSD1 protein stability in esophageal squamous cell carcinoma cells by inhibiting JNK signaling-dependent autophagy.
Liu X, Ye Z, Rao D, Chen Q, Zhang Z. | 03/7/2024 |
| Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease. | Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.
Wang E, Pan AL, Bagchi P, Rangaraju S, Seyfried NT, Ehrlich ME, Salton SR, Zhang B., Free PMC Article | 02/12/2024 |
| ARID1A loss activates MAPK signaling via DUSP4 downregulation. | ARID1A loss activates MAPK signaling via DUSP4 downregulation.
Mandal J, Yu ZC, Shih IM, Wang TL., Free PMC Article | 12/28/2023 |
| An integrative analysis of the single-cell transcriptome identifies DUSP4 as an exhaustion-associated gene in tumor-infiltrating CD8+ T cells. | An integrative analysis of the single-cell transcriptome identifies DUSP4 as an exhaustion-associated gene in tumor-infiltrating CD8+ T cells.
Zhao Y, Cai H, Ding X, Zhou X. | 05/1/2023 |
| DUSP4 inhibits autophagic cell death and apoptosis in colorectal cancer by regulating BCL2-Beclin1/Bax signaling. | DUSP4 inhibits autophagic cell death and apoptosis in colorectal cancer by regulating BCL2-Beclin1/Bax signaling.
Xu W, Nie C, Chen X. | 03/30/2023 |
| Investigating the Role of DUSP4 in Uveal Melanoma. | Investigating the Role of DUSP4 in Uveal Melanoma.
Aughton K, Sabat-Pospiech D, Barlow S, Coupland SE, Kalirai H., Free PMC Article | 01/11/2023 |
| Low expression of DUSP4 expression predicts unfavorable prognosis in gallbladder adenocarcinoma. | Low expression of DUSP4 expression predicts unfavorable prognosis in gallbladder adenocarcinoma.
Jee S, Sim J, Bang S, Park H, Myung J, Paik SS, Choi D, Kim Y, Kim H. | 11/5/2022 |
| DUSP4 Inactivation Leads to Reduced Extracellular SignalRegulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells. | DUSP4 Inactivation Leads to Reduced Extracellular Signal‒Regulated Kinase Activity through Upregulation of DUSP6 in Melanoma Cells.
Kamada H, Yasuhira S, Shibazaki M, Amano H, Maesawa C. | 08/27/2022 |
| Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma. | Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma.
Huang S, Ma Z, Zhou Q, Wang A, Gong Y, Li Z, Wang S, Yan Q, Wang D, Hou B, Zhang C., Free PMC Article | 07/30/2022 |
| Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease. | Metabolic Impact of MKP-2 Upregulation in Obesity Promotes Insulin Resistance and Fatty Liver Disease.
Fernando S, Sellers J, Smith S, Bhogoju S, Junkins S, Welch M, Willoughby O, Ghimire N, Secunda C, Barmanova M, Kumer SC, Min K, Lawan A., Free PMC Article | 07/2/2022 |
| Overexpression of dual-specificity phosphatases 4 and 13 attenuates transforming growth factor beta1-induced migration and drug resistance in A549 cells in vitro. | Overexpression of dual-specificity phosphatases 4 and 13 attenuates transforming growth factor β1-induced migration and drug resistance in A549 cells in vitro.
Guler S, Altunok TH, Sarioglu A, Zik B, Asmaz D, Kayapunar N, Sonmez O, Tepedelen BE, Yalcin A. | 05/7/2022 |
| Methylation of dual-specificity phosphatase 4 controls cell differentiation. | Methylation of dual-specificity phosphatase 4 controls cell differentiation.
Su H, Jiang M, Senevirathne C, Aluri S, Zhang T, Guo H, Xavier-Ferrucio J, Jin S, Tran NT, Liu SM, Sun CW, Zhu Y, Zhao Q, Chen Y, Cable L, Shen Y, Liu J, Qu CK, Han X, Klug CA, Bhatia R, Chen Y, Nimer SD, Zheng YG, Iancu-Rubin C, Jin J, Deng H, Krause DS, Xiang J, Verma A, Luo M, Zhao X., Free PMC Article | 02/12/2022 |
| Long non-coding RNA AFAP1-AS1 promotes thyroid cancer progression by sponging miR-204-3p and upregulating DUSP4. | Long non-coding RNA AFAP1-AS1 promotes thyroid cancer progression by sponging miR-204-3p and upregulating DUSP4.
Ma H, Shi Q, Fang J, Wang R, Zhao J, Lin S, Dong J, Zhang Y, Shen X, Chen J, Zhong Q. | 02/12/2022 |
| Lysine-Specific Histone Demethylase 1 Promotes Oncogenesis of the Esophageal Squamous Cell Carcinoma by Upregulating DUSP4. | Lysine-Specific Histone Demethylase 1 Promotes Oncogenesis of the Esophageal Squamous Cell Carcinoma by Upregulating DUSP4.
Han J, Ye S, Chen J, Wang K, Jin J, Zeng Z, Xue S. | 01/29/2022 |
| DUSP4 inhibits autophagic cell death in PTC by inhibiting JNK-BCL2-Beclin1 signaling. | DUSP4 inhibits autophagic cell death in PTC by inhibiting JNK-BCL2-Beclin1 signaling.
He H, Du Z, Lin J, Wu W, Yu Y. | 01/8/2022 |
| Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. | Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.
Ito T, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, Dutta S, Pal D, Paolella BR, Rothberg MV, Root DE, Johannessen CM, Parida L, Getz G, Vazquez F, Doench JG, Zamanighomi M, Sellers WR. | 01/1/2022 |
| Aberrant expression of DUSP4 is a specific phenomenon in betel quid-related oral cancer. | Aberrant expression of DUSP4 is a specific phenomenon in betel quid-related oral cancer.
Adhikari BR, Yoshida K, Paudel D, Morikawa T, Uehara O, Sato J, Muthumala M, Amaratunga P, Arakawa T, Chiba I, Abiko Y. | 12/18/2021 |
| DUSP4 promotes the carcinogenesis of CCRCC via negative regulation of autophagic death. | DUSP4 promotes the carcinogenesis of CCRCC via negative regulation of autophagic death.
Zeng X, Zhu C, Zhu X. | 10/30/2021 |
| DUSP4 appears to be a highly localized endogenous inhibitor of epileptic signaling in human neocortex. | DUSP4 appears to be a highly localized endogenous inhibitor of epileptic signaling in human neocortex.
Kirchner A, Bagla S, Dachet F, Loeb JA., Free PMC Article | 10/16/2021 |
| Expression of DUSP4 transcript variants as a potential biomarker for colorectal cancer. | Expression of DUSP4 transcript variants as a potential biomarker for colorectal cancer.
Varela T, Laizé V, Conceição N, Caldeira P, Marreiros A, Guerreiro H, Cancela ML. | 09/11/2021 |
| Low DUSP4 Expression Is Associated With Aggressive Phenotypes and Poor Prognosis in Gastric Cancer. | Low DUSP4 Expression Is Associated With Aggressive Phenotypes and Poor Prognosis in Gastric Cancer.
Bang S, Jee S, Kim H, Jang K, Park H, Myung JK, Choi D, Shin SJ, Paik SS., Free PMC Article | 07/31/2021 |
| miR1225p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression. | miR‑122‑5p suppresses the oncogenesis of PTC by inhibiting DUSP4 expression.
Hu N, Tian Y, Song Y, Zang L., Free PMC Article | 05/15/2021 |
| The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib. | The microRNA-429/DUSP4 axis regulates the sensitivity of colorectal cancer cells to nintedanib.
Cheng G, Li Y, Liu Z, Song X., Free PMC Article | 05/8/2021 |