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    DRD1 dopamine receptor D1 [ Homo sapiens (human) ]

    Gene ID: 1812, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC.

    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC.
    Grant CE, Flis AL, Toulabi L, Zingone A, Rossi E, Aploks K, Sheppard H, Ryan BM., Free PMC Article

    06/18/2024
    Dopamine D1-Receptor Organization Contributes to Functional Brain Architecture.

    Dopamine D1-Receptor Organization Contributes to Functional Brain Architecture.
    Pedersen R, Johansson J, Nordin K, Rieckmann A, Wåhlin A, Nyberg L, Bäckman L, Salami A., Free PMC Article

    03/21/2024
    Unravelling neurotransmitters impairment in primary progressive aphasias.

    Unravelling neurotransmitters impairment in primary progressive aphasias.
    Premi E, Dukart J, Mattioli I, Libri I, Pengo M, Gadola Y, Cotelli M, Manenti R, Binetti G, Gazzina S, Alberici A, Magoni M, Koch G, Gasparotti R, Padovani A, Borroni B., Free PMC Article

    10/25/2023
    DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons.

    DRD1 signaling modulates TrkB turnover and BDNF sensitivity in direct pathway striatal medium spiny neurons.
    Andreska T, Lüningschrör P, Wolf D, McFleder RL, Ayon-Olivas M, Rattka M, Drechsler C, Perschin V, Blum R, Aufmkolk S, Granado N, Moratalla R, Sauer M, Monoranu C, Volkmann J, Ip CW, Stigloher C, Sendtner M.

    10/11/2023
    Dopamine Receptor D1 Is Exempt from Transforming Growth Factor beta-Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts.

    Dopamine Receptor D1 Is Exempt from Transforming Growth Factor β-Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung Fibroblasts.
    Gao AY, Diaz Espinosa AM, Nguyen BBN, Link PA, Meridew J, Jones DL, Gibbard DF, Tschumperlin DJ, Haak AJ., Free PMC Article

    08/22/2023
    Inhibition of dopamine receptor D1 signaling promotes human bile duct cancer progression via WNT signaling.

    Inhibition of dopamine receptor D1 signaling promotes human bile duct cancer progression via WNT signaling.
    Yogo A, Masui T, Takaishi S, Masuo K, Chen R, Kasai Y, Nagai K, Anazawa T, Watanabe S, Sakamoto S, Watanabe A, Inagaki R, Nakagawa MM, Ogawa S, Seno H, Uemoto S, Hatano E., Free PMC Article

    04/5/2023
    Dopamine D1 receptor activation ameliorates ox-LDL-induced endothelial cell senescence via CREB/Nrf2 pathway.

    Dopamine D1 receptor activation ameliorates ox-LDL-induced endothelial cell senescence via CREB/Nrf2 pathway.
    Zhao Y, Li Y, Li H, Shi S.

    03/31/2023
    An Investigation into the Association Between Dopamine Receptor D1 Multilocus Genetic Variation, Multiparametric Magnetic Resonance Imaging, and Antidepressant Treatment.

    An Investigation into the Association Between Dopamine Receptor D1 Multilocus Genetic Variation, Multiparametric Magnetic Resonance Imaging, and Antidepressant Treatment.
    Sun Y, Wang X, Tian S, Chen Z, Wang H, Xue L, Yan R, Yao Z, Lu Q.

    06/18/2022
    Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis.

    Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis.
    Wieber K, Fleige L, Tsiami S, Reinders J, Braun J, Baraliakos X, Capellino S., Free PMC Article

    04/23/2022
    HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk.

    HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk.
    Yan Q, Wu X, Zhou P, Zhou Y, Li X, Liu Z, Tan H, Yao W, Xia Y, Zhu F., Free PMC Article

    03/5/2022
    Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.

    Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
    Zhuang Y, Krumm B, Zhang H, Zhou XE, Wang Y, Huang XP, Liu Y, Cheng X, Jiang Y, Jiang H, Zhang C, Yi W, Roth BL, Zhang Y, Xu HE., Free PMC Article

    01/22/2022
    Corticostriatal White Matter Integrity and Dopamine D1 Receptor Availability Predict Age Differences in Prefrontal Value Signaling during Reward Learning.

    Corticostriatal White Matter Integrity and Dopamine D1 Receptor Availability Predict Age Differences in Prefrontal Value Signaling during Reward Learning.
    de Boer L, Garzón B, Axelsson J, Riklund K, Nyberg L, Bäckman L, Guitart-Masip M., Free PMC Article

    12/25/2021
    Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study.

    Binding of Dopamine D1 Receptor and Noradrenaline Transporter in Individuals with Autism Spectrum Disorder: A PET Study.
    Kubota M, Fujino J, Tei S, Takahata K, Matsuoka K, Tagai K, Sano Y, Yamamoto Y, Shimada H, Takado Y, Seki C, Itahashi T, Aoki YY, Ohta H, Hashimoto RI, Zhang MR, Suhara T, Nakamura M, Takahashi H, Kato N, Higuchi M.

    12/18/2021
    Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward.

    Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward.
    Zhang R, Manza P, Tomasi D, Kim SW, Shokri-Kojori E, Demiral SB, Kroll DS, Feldman DE, McPherson KL, Biesecker CL, Wang GJ, Volkow ND., Free PMC Article

    11/22/2021
    Protein Interaction Studies for Understanding the Tremor Pathway in Parkinson's Disease.

    Protein Interaction Studies for Understanding the Tremor Pathway in Parkinson's Disease.
    Dogra N, Mani RJ, Katare DP.

    10/30/2021
    Smoking Genes: A Case-Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort.

    Smoking Genes: A Case-Control Study of Dopamine Transporter Gene (SLC6A3) and Dopamine Receptor Genes (DRD1, DRD2 and DRD3) Polymorphisms and Smoking Behaviour in a Malay Male Cohort.
    Ruzilawati AB, Islam MA, Muhamed SKS, Ahmad I., Free PMC Article

    09/4/2021
    Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.

    Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
    Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, He YH, Zhang DL, Zhang C, Hou GH, Liu H, Zhu L, Fu P, Yang S, Rosenbaum DM, Sun JP, Du Y, Zhang L, Yu X, Shao Z., Free PMC Article

    08/28/2021
    Structural insights into the human D1 and D2 dopamine receptor signaling complexes.

    Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
    Zhuang Y, Xu P, Mao C, Wang L, Krumm B, Zhou XE, Huang S, Liu H, Cheng X, Huang XP, Shen DD, Xu T, Liu YF, Wang Y, Guo J, Jiang Y, Jiang H, Melcher K, Roth BL, Zhang Y, Zhang C, Xu HE., Free PMC Article

    08/28/2021
    Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity.

    Activation of dopamine receptor D1 inhibits glioblastoma tumorigenicity by regulating autophagic activity.
    Yang K, Wei M, Yang Z, Fu Z, Xu R, Cheng C, Chen X, Chen S, Dammer E, Le W.

    08/7/2021
    DRD1 downregulation contributes to mechanical stretch-induced lung endothelial barrier dysfunction.

    DRD1 downregulation contributes to mechanical stretch-induced lung endothelial barrier dysfunction.
    Wang Y, Liu YJ, Xu DF, Zhang H, Xu CF, Mao YF, Lv Z, Zhu XY, Jiang L., Free PMC Article

    07/31/2021
    Heroin delay discounting and impulsivity: Modulation by DRD1 genetic variation.

    Heroin delay discounting and impulsivity: Modulation by DRD1 genetic variation.
    Moses TEH, Burmeister M, Greenwald MK., Free PMC Article

    06/26/2021
    Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.

    Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.
    Sun B, Feng D, Chu ML, Fish I, Lovera S, Sands ZA, Kelm S, Valade A, Wood M, Ceska T, Kobilka TS, Lebon F, Kobilka BK., Free PMC Article

    06/12/2021
    Constitutive activity of a G protein-coupled receptor, DRD1, contributes to human cerebral organoid formation.

    Constitutive activity of a G protein-coupled receptor, DRD1, contributes to human cerebral organoid formation.
    Wang Q, Dong X, Lu J, Hu T, Pei G., Free PMC Article

    05/22/2021
    Activation of D1 receptors affects human reactivity and flexibility to valued cues.

    Activation of D1 receptors affects human reactivity and flexibility to valued cues.
    Soutschek A, Kozak R, de Martinis N, Howe W, Burke CJ, Fehr E, Jetter A, Tobler PN., Free PMC Article

    04/3/2021
    Influence of DRD1 and DRD3 Polymorphisms in the Occurrence of Motor Effects in Patients with Sporadic Parkinson's Disease.

    Influence of DRD1 and DRD3 Polymorphisms in the Occurrence of Motor Effects in Patients with Sporadic Parkinson's Disease.
    Dos Santos EUD, Duarte EBC, Miranda LMR, Asano AGC, Asano NMJ, Maia MMD, de Souza PRE.

    01/23/2021
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