| Structural insights into double-stranded RNA recognition and transport by SID-1. | Structural insights into double-stranded RNA recognition and transport by SID-1.
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D. | 08/8/2024 |
| Structural basis for double-stranded RNA recognition by SID1. | Structural basis for double-stranded RNA recognition by SID1.
Wang R, Cong Y, Qian D, Yan C, Gong D., Free PMC Article | 06/25/2024 |
| consistent with previous studies, we fail to detect a requirement for sid-1 in dsRNA export, but demonstrate for the first time that SID-1 functions in the intestine to support environmental RNAi (eRNAi). | SID-1 Domains Important for dsRNA Import in Caenorhabditis elegans.
Whangbo JS, Weisman AS, Chae J, Hunter CP., Free PMC Article | 07/21/2018 |
| sid-1 is required for inheritance of silencing RNAs. dsRNA transit through the endocytosis pathway in early embryos is independent of sid-1. | SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans.
Wang E, Hunter CP., Free PMC Article | 02/10/2018 |
| Epigenetic silencing of the endogenous sid-1 locus is maintained by germline RNAi-mediated inheritance for up to 13 generations. | Stable Heritable Germline Silencing Directs Somatic Silencing at an Endogenous Locus.
Minkina O, Hunter CP., Free PMC Article | 09/9/2017 |
| The functional importance of SID-1 extracellular domain as a dsRNA binding domain that contributes to RNA transport. | Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.
Li W, Koutmou KS, Leahy DJ, Li M., Free PMC Article | 10/24/2015 |
| SID-1 is a dsRNA-selective dsRNA-gated channel. | SID-1 is a dsRNA-selective dsRNA-gated channel.
Shih JD, Hunter CP., Free PMC Article | 08/6/2011 |
| C. elegans expressing neuronal SID-1 showed RNAi phenotypes when fed with bacteria expressing dsRNA for known neuronal genes and for uncharacterized genes with no previously known neuronal phenotypes. | Enhanced neuronal RNAi in C. elegans using SID-1.
Calixto A, Chelur D, Topalidou I, Chen X, Chalfie M., Free PMC Article | 07/26/2010 |
| C. elegans can transport endogenous and exogenous RNA silencing signals between many different tissues via at least 2 SID-1 independent export pathways | Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1.
Jose AM, Smith JJ, Hunter CP., Free PMC Article | 01/21/2010 |
| Study shows that equivalent masses of long or short dsRNA accumulate in Drosophila S2 cells, indicating that size-dependent silencing is not due to size-selective transport through SID-1. | The SID-1 double-stranded RNA transporter is not selective for dsRNA length.
Shih JD, Fitzgerald MC, Sutherlin M, Hunter CP., Free PMC Article | 01/21/2010 |
| data indicate that systemic RNA interference in C. elegans involves SID-1-mediated intercellular transport of dsRNA | Transport of dsRNA into cells by the transmembrane protein SID-1.
Feinberg EH, Hunter CP. | 01/21/2010 |