| Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation. | Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.
Lin Y, Yang Q, Lin X, Liu X, Qian Y, Xu D, Cao N, Han X, Zhu Y, Hu W, He X, Yu Z, Kong X, Zhu L, Zhong Z, Liu K, Zhou B, Wang Y, Peng J, Zhu W, Wang J. | 02/22/2024 |
| Through a combination of sequencing studies on eighteen North Carolina macular dystrophy families, two novel overlapping duplications at the MCDR3 locus, in a gene desert downstream of IRX1 and upstream of ADAMTS16, have been reported. | Duplication events downstream of IRX1 cause North Carolina macular dystrophy at the MCDR3 locus.
Cipriani V, Silva RS, Arno G, Pontikos N, Kalhoro A, Valeina S, Inashkina I, Audere M, Rutka K, Puech B, Michaelides M, van Heyningen V, Lace B, Webster AR, Moore AT., Free PMC Article | 02/23/2019 |
| ADAMTS16 is novel gene with cancer-specific promoter hypermethylation in colorectal cancer, lung cancer and oral squamous cell carcinoma patients implicating ADAMTS16 as potential biomarker for these tumors. | Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers.
Kordowski F, Kolarova J, Schafmayer C, Buch S, Goldmann T, Marwitz S, Kugler C, Scheufele S, Gassling V, Németh CG, Brosch M, Hampe J, Lucius R, Röder C, Kalthoff H, Siebert R, Ammerpohl O, Reiss K., Free PMC Article | 01/12/2019 |
| The pregnancy loss rate seems to be affected by both ADAMTS-3 and ADAMTS-16. | ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.
Pekcan MK, Sarıkaya E, Tokmak A, Alışık M, Alkan A, Özakşit G, Erel Ö. | 04/29/2017 |
| Epistasis between single nucleotide polymorphisms within the TSHB and ADAMTS16 genes may increase the risk of premature ovarian failure in Korean women. | Epistasis between polymorphisms in TSHB and ADAMTS16 is associated with premature ovarian failure.
Pyun JA, Kim S, Cha DH, Kwack K. | 04/18/2015 |
| Data show that the expression of ADAMTS4, 9, 16 and was up-regulated during chondrogenesis, ADAMTS1 and 5 were down-regulated. | Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.
Boeuf S, Graf F, Fischer J, Moradi B, Little CB, Richter W. | 08/11/2012 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Results describe the distribution, regulation and function of human ADAMTS-16. | Characterization and regulation of ADAMTS-16.
Surridge AK, Rodgers UR, Swingler TE, Davidson RK, Kevorkian L, Norton R, Waters JG, Goldring MB, Parker AE, Clark IM., Free PMC Article | 01/21/2010 |
| Blood pressure is associated with SNPs of ADAMTS16 in human. | Positional identification of variants of Adamts16 linked to inherited hypertension.
Joe B, Saad Y, Dhindaw S, Lee NH, Frank BC, Achinike OH, Luu TV, Gopalakrishnan K, Toland EJ, Farms P, Yerga-Woolwine S, Manickavasagam E, Rapp JP, Garrett MR, Coe D, Apte SS, Rankinen T, Pérusse L, Ehret GB, Ganesh SK, Cooper RS, O'Connor A, Rice T, Weder AB, Chakravarti A, Rao DC, Bouchard C., Free PMC Article | 01/21/2010 |
| These studies provide the first evidence that ADAMTS-16 is an active protease and suggest a physiological role of ADAMTS-16 in ovarian follicles, at least during the pre-ovulatory phase. | FSH stimulates the expression of the ADAMTS-16 protease in mature human ovarian follicles.
Gao S, De Geyter C, Kossowska K, Zhang H. | 01/21/2010 |
| comparison of the effects of C-terminal truncation on the GAG-binding properties and aggrecanase activity of ADAMTS-5 relative to three other ADAMTS family members, ADAMTS-9, ADAMTS-16 and ADAMTS-18 | Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.
Zeng W, Corcoran C, Collins-Racie LA, Lavallie ER, Morris EA, Flannery CR. | 01/21/2010 |