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    Fabp5 fatty acid binding protein 5, epidermal [ Mus musculus (house mouse) ]

    Gene ID: 16592, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome.

    High levels of fatty acid-binding protein 5 excessively enhances fatty acid synthesis and proliferation of granulosa cells in polycystic ovary syndrome.
    Liu J, Li J, Wu X, Zhang M, Yan G, Sun H, Li D., Free PMC Article

    03/4/2024
    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis.

    Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis.
    Hao J, Yu J, Yorek MS, Yu CL, Pope RM, Chimenti MS, Xiong Y, Klingelhutz A, Jabbari A, Li B., Free PMC Article

    12/6/2023
    FABP5 is important for cognitive function and is an important regulator of the physiological effects and pharmacokinetics of acute Delta9 tetrahydrocannabinol inhalation in mice.

    FABP5 is important for cognitive function and is an important regulator of the physiological effects and pharmacokinetics of acute Δ9 tetrahydrocannabinol inhalation in mice.
    Penman SL, Roeder NM, Berthold EC, Senetra AS, Marion M, Richardson BJ, White O, Fearby NL, McCurdy CR, Hamilton J, Sharma A, Thanos PK.

    10/2/2023
    Polypyrimidine tract binding protein 1 exacerbates cardiac fibrosis by regulating fatty acid-binding protein 5.

    Polypyrimidine tract binding protein 1 exacerbates cardiac fibrosis by regulating fatty acid-binding protein 5.
    Chen Z, He C, Gao Z, Li Y, He Q, Wang Y, Cai C., Free PMC Article

    05/20/2023
    Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons.

    Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons.
    Guo Q, Kawahata I, Cheng A, Wang H, Jia W, Yoshino H, Fukunaga K., Free PMC Article

    01/21/2023
    FABP5 Deficiency Impaired Macrophage Inflammation by Regulating AMPK/NF-kappaB Signaling Pathway.

    FABP5 Deficiency Impaired Macrophage Inflammation by Regulating AMPK/NF-κB Signaling Pathway.
    Hou Y, Wei D, Bossila EA, Zhang Z, Li S, Bao J, Xu H, Zhang L, Zhao Y.

    12/24/2022
    FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism.

    FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism.
    Hou Y, Wei D, Zhang Z, Guo H, Li S, Zhang J, Zhang P, Zhang L, Zhao Y.

    11/26/2022
    Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/beta-catenin pathway.

    Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
    Lei Q, Yu Z, Li H, Cheng J, Wang Y., Free PMC Article

    10/1/2022
    Epidermal Fatty AcidBinding Protein Mediates Depilatory-Induced Acute Skin Inflammation.

    Epidermal Fatty Acid‒Binding Protein Mediates Depilatory-Induced Acute Skin Inflammation.
    Yin D, Hao J, Jin R, Yi Y, Bodduluri SR, Hua Y, Anand A, Deng Y, Haribabu B, Egilmez NK, Sauter ER, Li B., Free PMC Article

    06/25/2022
    Environmental enrichment sex-dependently rescues memory impairment in FABP5 KO mice not mediated by brain-derived neurotrophic factor.

    Environmental enrichment sex-dependently rescues memory impairment in FABP5 KO mice not mediated by brain-derived neurotrophic factor.
    Marion M, Hamilton J, Richardson B, Roeder N, Figueiredo A, Nubelo A, Hetelekides E, Penman S, Owada Y, Kagawa Y, Thanos PK.

    05/7/2022
    Salivary and Lacrimal Gland Alterations of the Epidermal Fatty Acid-Binding Protein (E-FABP) in Non-Obese Diabetic Mice.

    Salivary and Lacrimal Gland Alterations of the Epidermal Fatty Acid-Binding Protein (E-FABP) in Non-Obese Diabetic Mice.
    Dogru M, Kojima T, Simsek C, Nagata T, Tsubota K., Free PMC Article

    04/23/2022
    FABP5 Deficiency Impairs Mitochondrial Function and Aggravates Pathological Cardiac Remodeling and Dysfunction.

    FABP5 Deficiency Impairs Mitochondrial Function and Aggravates Pathological Cardiac Remodeling and Dysfunction.
    Gao S, Li G, Shao Y, Wei Z, Huang S, Qi F, Jiao Y, Li Y, Zhang C, Du J.

    02/12/2022
    A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models.

    A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models.
    Cheng A, Jia W, Kawahata I, Fukunaga K., Free PMC Article

    02/12/2022
    Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages.

    Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages.
    Guo Y, Liu Y, Zhao S, Xu W, Li Y, Zhao P, Wang D, Cheng H, Ke Y, Zhang X., Free PMC Article

    01/1/2022
    Fatty acid-binding protein 5 limits the generation of Foxp3(+) regulatory T cells through regulating plasmacytoid dendritic cell function in the tumor microenvironment.

    Fatty acid-binding protein 5 limits the generation of Foxp3(+) regulatory T cells through regulating plasmacytoid dendritic cell function in the tumor microenvironment.
    Kobayashi S, Wannakul T, Sekino K, Takahashi Y, Kagawa Y, Miyazaki H, Umaru BA, Yang S, Yamamoto Y, Owada Y.

    12/25/2021
    Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae.

    Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae.
    Bando Y, Tokuda N, Ogasawara Y, Onozawa G, Nagasaka A, Sakiyama K, Owada Y, Amano O., Free PMC Article

    08/28/2021
    Downregulation of FABP5 Suppresses the Proliferation and Induces the Apoptosis of Gastric Cancer Cells Through the Hippo Signaling Pathway.

    Downregulation of FABP5 Suppresses the Proliferation and Induces the Apoptosis of Gastric Cancer Cells Through the Hippo Signaling Pathway.
    Wang W, Liu Z, Chen X, Lu Y, Wang B, Li F, Lu S, Zhou X.

    08/14/2021
    Fatty acid-binding protein 5 controls lung tumor metastasis by regulating the maturation of natural killer cells in the lung.

    Fatty acid-binding protein 5 controls lung tumor metastasis by regulating the maturation of natural killer cells in the lung.
    Yang S, Kobayashi S, Sekino K, Kagawa Y, Miyazaki H, Kumar Shil S, Abdulaziz Umaru B, Wannakul T, Owada Y.

    07/17/2021
    FABP5 Is a Sensitive Marker for Lipid-Rich Macrophages in the Luminal Side of Atherosclerotic Lesions.

    FABP5 Is a Sensitive Marker for Lipid-Rich Macrophages in the Luminal Side of Atherosclerotic Lesions.
    Umbarawan Y, Enoura A, Ogura H, Sato T, Horikawa M, Ishii T, Sunaga H, Matsui H, Yokoyama T, Kawakami R, Maeno T, Setou M, Kurabayashi M, Iso T.

    06/12/2021
    The Fabp5/calnexin complex is a prerequisite for sensitization of mice to experimental autoimmune encephalomyelitis.

    The Fabp5/calnexin complex is a prerequisite for sensitization of mice to experimental autoimmune encephalomyelitis.
    Paskevicius T, Jung J, Pujol M, Eggleton P, Qin W, Robinson A, Gutowski N, Holley J, Smallwood M, Newcombe J, Zochodne D, Chen XZ, Tang J, Kraus A, Michalak M, Agellon LB.

    04/24/2021
    Fabp4/5 knockout mice demonstrate that glucose is preferentially utilized for biomass synthesis rather than ATP production during pressure-overload-induced cardiac hypertrophy and that the efficient supplementation of energy substrates may restore cardiac dysfunction caused by energy insufficiency.

    Glucose is preferentially utilized for biomass synthesis in pressure-overloaded hearts: evidence from fatty acid-binding protein-4 and -5 knockout mice.
    Umbarawan Y, Syamsunarno MRAA, Koitabashi N, Yamaguchi A, Hanaoka H, Hishiki T, Nagahata-Naito Y, Obinata H, Sano M, Sunaga H, Matsui H, Tsushima Y, Suematsu M, Kurabayashi M, Iso T., Free PMC Article

    08/17/2019
    The findings of this study suggest that genetic deletion, but not pharmacological inhibiton, of FABP5 affects sucrose intake and antidepressant-related behavior.

    Fatty acid-binding proteins 5 and 7 gene deletion increases sucrose consumption and diminishes forced swim immobility time.
    Hamilton J, Koumas C, Clavin BH, Marion M, Figueiredo A, Gonzalez S, O'Rourke JR, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK., Free PMC Article

    08/3/2019
    FABP4/5 have crucial roles in nutrient homeostasis during prolonged fasting for maintaining exercise endurance capacity.

    Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice.
    Iso T, Haruyama H, Sunaga H, Matsui M, Matsui H, Tanaka R, Umbarawan Y, Syamsunarno MRAA, Yokoyama T, Kurabayashi M., Free PMC Article

    06/22/2019
    our data suggest an unknown function of E-FABP in prevention of skin tumor development, and offer E-FABP as a therapeutic target for improving skin innate immunity in chemical-induced skin tumor prevention.

    Epidermal FABP Prevents Chemical-Induced Skin Tumorigenesis by Regulation of TPA-Induced IFN/p53/SOX2 Pathway in Keratinocytes.
    Zhang Y, Hao J, Zeng J, Li Q, Rao E, Sun Y, Liu L, Mandal A, Landers VD, Morris RJ, Cleary MP, Suttles J, Li B., Free PMC Article

    06/15/2019
    This study demonstrated the role of FABPs may play an important role in drug-seeking behavior under stressful conditions.

    Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels.
    Hamilton J, Marion M, Figueiredo A, Clavin BH, Deutsch D, Kaczocha M, Haj-Dahmane S, Thanos PK., Free PMC Article

    11/24/2018
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