Modulation of Alzheimer's disease brain pathology in mice by gut bacterial depletion: the role of IL-17a. | Modulation of Alzheimer's disease brain pathology in mice by gut bacterial depletion: the role of IL-17a. Hao W, Luo Q, Tomic I, Quan W, Hartmann T, Menger MD, Fassbender K, Liu Y., Free PMC Article | 10/29/2024 |
Shifting phenotype and differentiation of CD11b[+]Gr.1[+] immature heterogeneous myeloid derived adjuster cells support inflammation and induce regulators of IL17A in imiquimod induced psoriasis. | Shifting phenotype and differentiation of CD11b(+)Gr.1(+) immature heterogeneous myeloid derived adjuster cells support inflammation and induce regulators of IL17A in imiquimod induced psoriasis. Sarkar D, Pramanik A, Das D, Bhattacharyya S. | 09/4/2024 |
Impact of IL-1beta on lung pathology caused by Mycobacterium abscessus infection and its association with IL-17 production. | Impact of IL-1β on lung pathology caused by Mycobacterium abscessus infection and its association with IL-17 production. Ahn JH, Jung DH, Kim DY, Lee TS, Kim YJ, Lee YJ, Seo IS, Kim WG, Cho YJ, Shin SJ, Park JH. | 07/31/2024 |
Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs. | Combinatorial actions of IL-22 and IL-17 drive optimal immunity to oral candidiasis through SPRRs. Aggor FEY, Bertolini M, Coleman BM, Taylor TC, Ponde NO, Gaffen SL., Free PMC Article | 07/11/2024 |
The impact of IL-10 and IL-17 on myeloid-derived suppressor cells in vitro and in vivo in a murine model of asthma. | The impact of IL-10 and IL-17 on myeloid-derived suppressor cells in vitro and in vivo in a murine model of asthma. Vetter C, Schieb J, Vedder N, Lange T, Brunn T, van Geffen C, Gercke P, Kolahian S. | 07/9/2024 |
Haematopoietic innate interleukin 17A production drives immunopathology in female mouse genital Chlamydia muridarum infection. | Haematopoietic innate interleukin 17A production drives immunopathology in female mouse genital Chlamydia muridarum infection. Armitage CW, Bryan ER, Trim L, Palframan E, Wager L, Beagley KW, Carey AJ. | 04/29/2024 |
Dual blockade of interleukin-17A and interleukin-17F as a therapeutic strategy for liver fibrosis: Investigating the potential effect and mechanism of brodalumab. | Dual blockade of interleukin-17A and interleukin-17F as a therapeutic strategy for liver fibrosis: Investigating the potential effect and mechanism of brodalumab. Matsuda KM, Kotani H, Hisamoto T, Kuzumi A, Fukasawa T, Yoshizaki-Ogawa A, Sato S, Yoshizaki A. | 04/25/2024 |
Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection. | Disruption of IL-17-mediated immunosurveillance in the respiratory mucosa results in invasive Streptococcus pyogenes infection. Mills JL, Lepletier A, Ozberk V, Dooley J, Kaden J, Calcutt A, Huo Y, Hicks A, Zaid A, Good MF, Pandey M., Free PMC Article | 04/12/2024 |
MicroRNA-150 Deletion Reduces the Occurrence and Severity of Rheumatoid Arthritis by Inhibiting IL-17. | MicroRNA-150 Deletion Reduces the Occurrence and Severity of Rheumatoid Arthritis by Inhibiting IL-17. Zhang A, Zheng Q. | 03/13/2024 |
[Mechanism of IL-17 Signaling Pathway in Spleen Inflammatory Response Induced by Altitude Hypoxia in Mice]. | [Mechanism of IL-17 Signaling Pathway in Spleen Inflammatory Response Induced by Altitude Hypoxia in Mice]. Yong S, Guo Y, Chen X, Xu Y, Hu Y., Free PMC Article | 03/12/2024 |
IL-17A deficiency alleviates cerebral ischemia-reperfusion injury via activating ERK/MAPK pathway in hippocampal CA1 region. | IL-17A deficiency alleviates cerebral ischemia-reperfusion injury via activating ERK/MAPK pathway in hippocampal CA1 region. Li Y, Zhang Q, Wang X, Xu F, Niu J, Zhao J, Wang Q. | 03/5/2024 |
Distinct cross talk of IL-17 & TGF-beta with the immature CD11c[+] TRAF6[(-/-)] -null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo. | Distinct cross talk of IL-17 & TGF-β with the immature CD11c(+) TRAF6((-/-)) -null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo. Liu YCG, Teng AY., Free PMC Article | 02/29/2024 |
The m[6] A modification of Il17a in CD4[+] T cells promotes inflammation in psoriasis. | The m(6) A modification of Il17a in CD4(+) T cells promotes inflammation in psoriasis. Yuan L, Chen S, Ding K, Wang X, Lv W, Liu Y, He S, Yu Y, Yang B, Huang T. | 02/7/2024 |
Exogenous IL-17A Alleviates Social Behavior Deficits and Increases Neurogenesis in a Murine Model of Autism Spectrum Disorders. | Exogenous IL-17A Alleviates Social Behavior Deficits and Increases Neurogenesis in a Murine Model of Autism Spectrum Disorders. Willinger Y, Friedland Cohen DR, Turgeman G., Free PMC Article | 01/16/2024 |
Comparing HD knockin pigs and mice reveals the pathological role of IL-17. | Comparing HD knockin pigs and mice reveals the pathological role of IL-17. Jia Q, Bai D, Zheng X, Zhu L, Ou K, Wang X, Tong H, Zhang Y, Wang J, Zeng J, Yan S, Li S, Li XJ, Yin P. | 01/5/2024 |
Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium. | Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium. Chen Y, Bounds SE, Ma X, Karmoker JR, Liu Y, Ma JX, Cai J., Free PMC Article | 12/20/2023 |
Molecular mechanism of interleukin-17A regulating airway epithelial cell ferroptosis based on allergic asthma airway inflammation. | Molecular mechanism of interleukin-17A regulating airway epithelial cell ferroptosis based on allergic asthma airway inflammation. Song J, Zhang H, Tong Y, Wang Y, Xiang Q, Dai H, Weng C, Wang L, Fan J, Shuai Y, Lai C, Fang X, Chen M, Bao J, Zhang W., Free PMC Article | 12/20/2023 |
RORgammat[+] c-Maf[+] Vgamma4[+] gammadelta T cells are generated in the adult thymus but do not reach the periphery. | RORγt(+) c-Maf(+) Vγ4(+) γδ T cells are generated in the adult thymus but do not reach the periphery. Yang T, Barros-Martins J, Wang Z, Wencker M, Zhang J, Smout J, Gambhir P, Janssen A, Schimrock A, Georgiev H, León-Lara X, Weiss S, Huehn J, Prinz I, Krueger A, Foerster R, Walzer T, Ravens S. | 12/5/2023 |
Protective role of IL-17-producing gammadelta T cells in a laser-induced choroidal neovascularization mouse model. | Protective role of IL-17-producing γδ T cells in a laser-induced choroidal neovascularization mouse model. Chang YH, Hsing CH, Chiu CJ, Wu YR, Hsu SM, Hsu YH., Free PMC Article | 11/29/2023 |
Modulating asthma-COPD overlap responses with IL-17 inhibition. | Modulating asthma-COPD overlap responses with IL-17 inhibition. Camargo LDN, Righetti RF, de Almeida FM, Dos Santos TM, Fukuzaki S, Martins NAB, Barbeiro MC, Saraiva-Romanholo BM, Lopes FDTQDS, Leick EA, Prado CM, Tibério IFLC., Free PMC Article | 11/20/2023 |
Impact of IL-17-producing gammadelta T cells on chronic otitis media induced by nontypeable Haemophilus influenzae in a mouse model. | Impact of IL-17-producing γδ T cells on chronic otitis media induced by nontypeable Haemophilus influenzae in a mouse model. Hirano T, Kawano T, Kadowaki Y, Moriyama M, Umemoto S, Yoshinaga K, Matsunaga T, Suzuki M. | 11/14/2023 |
Interleukin-17A plays a key role in pulmonary fibrosis following Propionibacterium acnes-induced sarcoidosis-like inflammation. | Interleukin-17A plays a key role in pulmonary fibrosis following Propionibacterium acnes-induced sarcoidosis-like inflammation. Jiang D, Xiao H, Zheng X, Dong R, Zhang H, Dai H., Free PMC Article | 11/3/2023 |
Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica. | Exercise training inhibits macrophage-derived IL-17A-CXCL5-CXCR2 inflammatory axis to attenuate pulmonary fibrosis in mice exposed to silica. Jin F, Li Y, Gao X, Yang X, Li T, Liu S, Wei Z, Li S, Mao N, Liu H, Cai W, Xu H, Zhang H. | 10/30/2023 |
IL-4 receptor alpha blockade dampens allergic inflammation and upregulates IL-17A expression to promote Saureus clearance in antigen sensitized mouse skin. | IL-4 receptor alpha blockade dampens allergic inflammation and upregulates IL-17A expression to promote Saureus clearance in antigen sensitized mouse skin. Leyva-Castillo JM, McGurk A, Strakosha M, Vega-Mendoza D, Smith SEM, Stafstrom K, Elkins M, Chou J, Wang YH, Geha RS., Free PMC Article | 10/10/2023 |
IL-17a-producing gammadeltaT cells and NKG2D signaling mediate bacterial endotoxin-induced neonatal lung injury: implications for bronchopulmonary dysplasia. | IL-17a-producing γδT cells and NKG2D signaling mediate bacterial endotoxin-induced neonatal lung injury: implications for bronchopulmonary dysplasia. Cui TX, Brady AE, Zhang YJ, Anderson C, Popova AP., Free PMC Article | 09/29/2023 |