| Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male. | Y-chromosome haplogroups and Azoospermia Factor (AZF) analysis in Tunisian infertile male.
Ghorbel M, Baklouti-Gargouri S, Keskes R, Sellami A, McElreavy K, Ammar-Keskes L. | 01/11/2024 |
| CXCL10 Recruitment of gammadelta T Cells into the Hypoxic Bone Marrow Environment Leads to IL17 Expression and Multiple Myeloma Progression. | CXCL10 Recruitment of γδ T Cells into the Hypoxic Bone Marrow Environment Leads to IL17 Expression and Multiple Myeloma Progression.
Wang J, Peng Z, Guo J, Wang Y, Wang S, Jiang H, Wang M, Xie Y, Li X, Hu M, Xie Y, Cheng H, Li T, Jia L, Song J, Wang Y, Hou J, Liu Z. | 10/5/2023 |
| Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis. | Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis.
Nongthombam PD, Malini SS. | 05/24/2023 |
| Partial-AZFc deletions in Chilean men with primary spermatogenic impairment: gene dosage and Y-chromosome haplogroups. | Partial-AZFc deletions in Chilean men with primary spermatogenic impairment: gene dosage and Y-chromosome haplogroups.
Lardone MC, Ortega V, Ortiz E, Flórez M, Piottante A, Ebensperger M, Flores S, Pezo P, Orellana M, Moraga M, Castro A., Free PMC Article | 07/10/2021 |
| There was an increased frequency of DAZ microdeletion in blood samples from oligozoospermic and near azoospermic patients. A high frequency of DAZ microdeletion was observed in the sperm of patients with no DAZ microdeletion in their leukocytes compared to control. The results might be indicative of DAZ microdeletion induction during spermatogenesis. | High frequency of de novo DAZ microdeletion in sperm nuclei of subfertile men: possible involvement of genome instability in idiopathic male infertility.
Mozdarani H, Ghoraeian P, Mozdarani S, Fallahi P, Mohseni-Meybodi A. | 11/3/2018 |
| We investigated partial deletion of AZFc region and DAZ copy number in a population of Iranian infertile men and normozoospermic controls. | Analysis of partial azoospermia factor c deletion and DAZ copy number in azoospermia and severe oligozoospermia.
Alimardanian L, Saliminejad K, Razi S, Ahani A. | 02/18/2017 |
| Susceptibility of gr/gr rearrangements to azoospermia or oligozoospermia is dependent on DAZ and CDY1 gene copy deletions. | Susceptibility of gr/gr rearrangements to azoospermia or oligozoospermia is dependent on DAZ and CDY1 gene copy deletions.
Sen S, Ambulkar P, Hinduja I, Zaveri K, Gokral J, Pal A, Modi D., Free PMC Article | 04/30/2016 |
| Overexpression of DAZ1 is associated with breast tumors. | Transcriptome analysis of the cancer/testis genes, DAZ1, AURKC, and TEX101, in breast tumors and six breast cancer cell lines.
Mobasheri MB, Shirkoohi R, Zendehdel K, Jahanzad I, Talebi S, Afsharpad M, Modarressi MH. | 01/30/2016 |
| Studies indicate that partial RNA-binding proteins DAZ1/2 deletion was associated wih male infertility, but partial RNA-binding proteins DAZ3/4 deletion was not associated with male infertility. | Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.
Zhang Y, Li M, Xiao F, Teng R, Zhang C, Lan A, Gu K, Li J, Wang D, Li H, Jiang L, Zeng S, He M, Huang Y, Guo P, Zhang X, Yang X. | 11/28/2015 |
| We did not found any statistically significant genetic association between DAZ alleles and idiopathic male infertility | [The association between DAZ T > C polymorphism and idiopathic male infertility risk in north of Iran].
Hadiyan SP, Mashayekhi F, Salehi Z. | 05/30/2015 |
| genetic association study in Chinese population: Data suggest that combined patterns of copy number abnormality in DAZ1 (deleted in azoospermia 1) and/or BPY2 (basic charge Y-linked protein 2) are associated with spermatogenic impairment/azoospermia. | Gene copy number alterations in the azoospermia-associated AZFc region and their effect on spermatogenic impairment.
Lu C, Jiang J, Zhang R, Wang Y, Xu M, Qin Y, Lin Y, Guo X, Ni B, Zhao Y, Diao N, Chen F, Shen H, Sha J, Xia Y, Hu Z, Wang X. | 04/4/2015 |
| There appears to be an asociation of DAZ1/DAZ2 deletion with spermatogenic impairment and male infertility in the South Chinese population. | Association of DAZ1/DAZ2 deletion with spermatogenic impairment and male infertility in the South Chinese population.
Li Q, Qiao D, Song NH, Ding Y, Wang ZJ, Yang J, Wang W, Yin CJ. | 10/4/2014 |
| Report the prevalence of variations in the AZFc region of the human Y chromosome in infertile men. | Analysis of DAZ gene expression in a partial AZFc deletion of the human Y chromosome.
Kim B, Lee W, Rhee K, Kim SW, Paick JS. | 09/6/2014 |
| genetic association studies in Han population in China: Data suggest that AZF1/DAZ1 duplications underlie genetic predisposition of Y-chromosome haplogroup K* to spermatogenic impairment (azoospermia/oligospermia) in the population studied. | DAZ duplications confer the predisposition of Y chromosome haplogroup K* to non-obstructive azoospermia in Han Chinese populations.
Lu C, Wang Y, Zhang F, Lu F, Xu M, Qin Y, Wu W, Li S, Song L, Yang S, Wu D, Jin L, Shen H, Sha J, Xia Y, Hu Z, Wang X. | 03/22/2014 |
| The methylation patterns of CpG island (CGI) in the DAZ gene promoter region were different between somatic cells and spermatic cells | Lack of association between DAZ gene methylation patterns and spermatogenic failure.
Wu W, Lu C, Xia Y, Shen O, Ji G, Gu A, Song L, Wang X. | 05/31/2010 |
| human DAZL (deleted in azoospermia-like) functions in primordial germ-cell formation, whereas closely related genes DAZ and BOULE (also called BOLL) promote later stages of meiosis and development of haploid gametes | Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation.
Kee K, Angeles VT, Flores M, Nguyen HN, Reijo Pera RA., Free PMC Article | 01/21/2010 |
| All four DAZ genes are expressed in the human testis, and their products are highly polymorphic among men | Polymorphic expression of DAZ proteins in the human testis.
Kim B, Lee Y, Kim Y, Lee KH, Chun S, Rhee K, Seo JT, Kim SW, Paick JS. | 01/21/2010 |
| PCR and FISH demonstrated tandem duplication/multiplication of the SRY and DAZ genes in the two Turner Syndrome patients having intact Y chromosome in >85% cells | Startling mosaicism of the Y-chromosome and tandem duplication of the SRY and DAZ genes in patients with Turner Syndrome.
Premi S, Srivastava J, Panneer G, Ali S., Free PMC Article | 01/21/2010 |
| complete DAZ deletion is a frequent genetic cause of severe oligozoospermia, and DAZ1/DAZ2 deletion is a high risk factor for the disease | [Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].
A ZC, Yang Y, Zhang SZ, Lin L. | 01/21/2010 |
| Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) | A frequent partial AZFc deletion does not render an increased risk of spermatogenic impairment in East Asians.
Zhang F, Li Z, Wen B, Jiang J, Shao M, Zhao Y, He Y, Song X, Qian J, Lu D, Jin L. | 03/18/2009 |
| AZFc subdeletions do not seem to cause severe impairment of spermatogenesis in Chilean men. | AZFc partial deletions in Chilean men with severe spermatogenic failure.
Lardone MC, Parodi DA, Ebensperger M, Peñaloza P, Cornejo V, Valdevenito R, Pommer R, Castro A. | 01/21/2010 |
| The data show no relationship between 'gr/gr' AZC gene deletion and cryptorchidism. | Partial AZFc deletions in infertile men with cryptorchidism.
Giachini C, Nuti F, Marinari E, Forti G, Krausz C. | 01/21/2010 |
| AZFc rearrangements/polymorphisms are transmitted to sons and may represent a risk factor for decreased testis function and male subfertility, which needs confirmation in further studies in larger cohorts | Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.
Mau Kai C, Juul A, McElreavey K, Ottesen AM, Garn ID, Main KM, Loft A, Jørgensen N, Skakkebaek NE, Andersen AN, Rajpert-De Meyts E, Mau Kai C, Juul A, McElreavey K, Ottesen AM, Garn ID, Main KM, Loft A, Jørgensen N, Skakkebaek NE, Andersen AN, Rajpert-De Meyts E. | 01/21/2010 |
| The frequency of partial copy deletion of DAZ gene in Chinese idiopathic azoospermia or severe oligozoospermia patients is much higher, suggesting that the deletion of DAZ1/DAZ2 may be one of the important factors of spermatogenesis damage. | [Idiopathic male infertility and partial copy deletion of DAZ gene family].
Yang Y, Xiao C, Zhang S, Lin L, Wei W. | 01/21/2010 |
| deletions of two DAZ gene copies are compatible with normal spermatogenesis and fertility. | Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number.
Mau Kai C, Juul A, McElreavey K, Ottesen AM, Garn ID, Main KM, Loft A, Jørgensen N, Skakkebaek NE, Andersen AN, Rajpert-De Meyts E, Mau Kai C, Juul A, McElreavey K, Ottesen AM, Garn ID, Main KM, Loft A, Jørgensen N, Skakkebaek NE, Andersen AN, Rajpert-De Meyts E. | 01/21/2010 |