| Effects of E2 on the IDO1-mediated metabolic KYN pathway in OVX female mice. | Effects of E2 on the IDO1-mediated metabolic KYN pathway in OVX female mice.
Jiang X, Yu X, Hu S, Dai H, Zhang H, Hang Y, Xie X, Yang Y, Wu F., Free PMC Article | 11/6/2024 |
| Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma gondii infection. | Decidual natural killer cells dysfunction is caused by IDO downregulation in dMDSCs with Toxoplasma gondii infection.
Wang Y, Zhao X, Li Z, Wang W, Jiang Y, Zhang H, Liu X, Ren Y, Xu X, Hu X., Free PMC Article | 06/7/2024 |
| Indoleamine 2, 3-dioxygenase 1 activation in macrophage exacerbates hepatic ischemia-reperfusion injury by triggering hepatocyte ferroptosis. | Indoleamine 2, 3-dioxygenase 1 activation in macrophage exacerbates hepatic ischemia-reperfusion injury by triggering hepatocyte ferroptosis.
Ma S, Li J, Ye H, Wu C, Zhang J, Xu S, Song Y, Gu Y, Gao L. | 03/27/2024 |
| Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis. | Indoleamine 2,3-dioxygenase 1-mediated iron metabolism in macrophages contributes to lipid deposition in nonalcoholic steatohepatitis.
Wu C, Li J, Jia H, Zhao J, Qin M, Shi H, Liu C, Lin J, Cai M, Gu Y, Liu B, Gao L. | 03/26/2024 |
| Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1alpha overexpression or ablation of IDO1 or CD38. | Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.
Johnson EE, Southern WM, Doud B, Steiger B, Razzoli M, Bartolomucci A, Ervasti JM., | 03/25/2024 |
| Upregulation of IDO gene expression reduces the immunogenicity of epidermal cells and strengthens the immune protection of epidermal cells during transplantation treatment of wounds. | Upregulation of IDO gene expression reduces the immunogenicity of epidermal cells and strengthens the immune protection of epidermal cells during transplantation treatment of wounds.
Zhang K, Liu X, Luo P, Li Z, Zhao H, Li D, Liu Z, Zhang B, Shen C. | 02/4/2024 |
| Interactions of Indoleamine 2,3-dioxygenase-expressing LAMP3[+] dendritic cells with CD4[+] regulatory T cells and CD8[+] exhausted T cells: synergistically remodeling of the immunosuppressive microenvironment in cervical cancer and therapeutic implications. | Interactions of Indoleamine 2,3-dioxygenase-expressing LAMP3(+) dendritic cells with CD4(+) regulatory T cells and CD8(+) exhausted T cells: synergistically remodeling of the immunosuppressive microenvironment in cervical cancer and therapeutic implications.
Qu X, Wang Y, Jiang Q, Ren T, Guo C, Hua K, Qiu J., Free PMC Article | 11/14/2023 |
| Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency Inhibits Pathological Cardiac Hypertrophy. | Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency Inhibits Pathological Cardiac Hypertrophy.
Wang Y, Song J, Yu K, Nie D, Zhao C, Jiao L, Wang Z, Zhou L, Wang F, Yu Q, Zhang S, Wen Z, Wu J, Wang CY, Wang DW, Cheng J, Zhao C. | 09/27/2023 |
| IDO Regulates Macrophage Functions by Inhibiting the CCL2/CCR2 Signaling Pathway in Fungal Keratitis. | IDO Regulates Macrophage Functions by Inhibiting the CCL2/CCR2 Signaling Pathway in Fungal Keratitis.
Yu F, Jiang W, Zhang L, Jiang N. | 07/4/2023 |
| Dendritic cell-expressed IDO alleviates atherosclerosis by expanding CD4[+]CD25[+]Foxp3[+]Tregs through IDO-Kyn-AHR axis. | Dendritic cell-expressed IDO alleviates atherosclerosis by expanding CD4(+)CD25(+)Foxp3(+)Tregs through IDO-Kyn-AHR axis.
Wang F, Liu M, Ma D, Cai Z, Liu L, Wang J, Zhang W, Zhao L, Zhai C, Xu Y. | 03/8/2023 |
| The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma. | The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma.
Orecchini E, Belladonna ML, Pallotta MT, Volpi C, Zizi L, Panfili E, Gargaro M, Fallarino F, Rossini S, Suvieri C, Macchiarulo A, Bicciato S, Mondanelli G, Orabona C., Free PMC Article | 02/10/2023 |
| Effects of Ozone on Sickness and Depressive-like Behavioral and Biochemical Phenotypes and Their Regulation by Serum Amyloid A in Mice. | Effects of Ozone on Sickness and Depressive-like Behavioral and Biochemical Phenotypes and Their Regulation by Serum Amyloid A in Mice.
Baumann KK, Liang WS, Quaranta DV, Wilson ML, Asrat HS, Thysell JA, Sarchi AV, Banks WA, Erickson MA., Free PMC Article | 02/4/2023 |
| The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression. | The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
Nguyen DT, Kleczko EK, Dwivedi N, Monaghan MT, Gitomer BY, Chonchol MB, Clambey ET, Nemenoff RA, Klawitter J, Hopp K., Free PMC Article | 01/21/2023 |
| Indoleamine 2,3-dioxygenase 1 signaling orchestrates immune tolerance in Echinococcus multilocularis-infected mice. | Indoleamine 2,3-dioxygenase 1 signaling orchestrates immune tolerance in Echinococcus multilocularis-infected mice.
Meng R, Fu Y, Zhang Y, Mou Y, Liu G, Fan H., Free PMC Article | 12/3/2022 |
| USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer. | USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer.
Shi D, Wu X, Jian Y, Wang J, Huang C, Mo S, Li Y, Li F, Zhang C, Zhang D, Zhang H, Huang H, Chen X, Wang YA, Lin C, Liu G, Song L, Liao W., Free PMC Article | 10/8/2022 |
| Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication. | Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.
Gargaro M, Scalisi G, Manni G, Briseño CG, Bagadia P, Durai V, Theisen DJ, Kim S, Castelli M, Xu CA, Meyer Zu Hörste G, Servillo G, Della Fazia MA, Mencarelli G, Ricciuti D, Padiglioni E, Giacchè N, Colliva C, Pellicciari R, Calvitti M, Zelante T, Fuchs D, Orabona C, Boon L, Bessede A, Colonna M, Puccetti P, Murphy TL, Murphy KM, Fallarino F., Free PMC Article | 07/2/2022 |
| Genetic Deficiency of Indoleamine 2,3-dioxygenase Aggravates Vascular but Not Liver Disease in a Nonalcoholic Steatohepatitis and Atherosclerosis Comorbidity Model. | Genetic Deficiency of Indoleamine 2,3-dioxygenase Aggravates Vascular but Not Liver Disease in a Nonalcoholic Steatohepatitis and Atherosclerosis Comorbidity Model.
Arora A, Tripodi GL, Kareinen I, Berg M, Forteza MJ, Gisterå A, Griepke S, Casagrande FB, Martins JO, Abdalla DSP, Cole J, Monaco C, Ketelhuth DFJ., Free PMC Article | 05/21/2022 |
| Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses. | Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses.
Lightman SM, Peresie JL, Carlson LM, Holling GA, Honikel MM, Chavel CA, Nemeth MJ, Olejniczak SH, Lee KP., Free PMC Article | 02/19/2022 |
| Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway. | Hypoxic preconditioning protects against ischemic kidney injury through the IDO1/kynurenine pathway.
Torosyan R, Huang S, Bommi PV, Tiwari R, An SY, Schonfeld M, Rajendran G, Kavanaugh MA, Gibbs B, Truax AD, Bohney S, Calcutt MW, Kerr EW, Leonardi R, Gao P, Chandel NS, Kapitsinou PP., Free PMC Article | 02/12/2022 |
| The Role of Indoleamine 2,3-Dioxygenase in Renal Tubular Epithelial Cells Senescence under Anoxia or Reoxygenation. | The Role of Indoleamine 2,3-Dioxygenase in Renal Tubular Epithelial Cells Senescence under Anoxia or Reoxygenation.
Eleftheriadis T, Pissas G, Filippidis G, Liakopoulos V, Stefanidis I., Free PMC Article | 01/22/2022 |
| IDO1 Signaling through GCN2 in a Subpopulation of Gr-1(+) Cells Shifts the IFNgamma/IL6 Balance to Promote Neovascularization. | IDO1 Signaling through GCN2 in a Subpopulation of Gr-1(+) Cells Shifts the IFNγ/IL6 Balance to Promote Neovascularization.
Dey S, Mondal A, DuHadaway JB, Sutanto-Ward E, Laury-Kleintop LD, Thomas S, Prendergast GC, Mandik-Nayak L, Muller AJ. | 01/8/2022 |
| Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells. | Characterizing the distributions of IDO-1 expressing macrophages/microglia in human and murine brains and evaluating the immunological and physiological roles of IDO-1 in RAW264.7/BV-2 cells.
Ji R, Ma L, Chen X, Sun R, Zhang L, Saiyin H, Wei W., Free PMC Article | 12/25/2021 |
| Indoleamine-2,3-Dioxygenase Activates Wnt/beta-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury. | Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.
Pan B, Zhang H, Hong Y, Ma M, Wan X, Cao C. | 11/27/2021 |
| Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma. | Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Ladomersky E, Zhai L, Lauing KL, Bell A, Xu J, Kocherginsky M, Zhang B, Wu JD, Podojil JR, Platanias LC, Mochizuki AY, Prins RM, Kumthekar P, Raizer JJ, Dixit K, Lukas RV, Horbinski C, Wei M, Zhou C, Pawelec G, Campisi J, Grohmann U, Prendergast GC, Munn DH, Wainwright DA., Free PMC Article | 11/27/2021 |
| Murine endometrial-derived mesenchymal stem cells suppress experimental autoimmune encephalomyelitis depending on indoleamine-2,3-dioxygenase expression. | Murine endometrial-derived mesenchymal stem cells suppress experimental autoimmune encephalomyelitis depending on indoleamine-2,3-dioxygenase expression.
Manganeli Polonio C, Longo de Freitas C, Garcia de Oliveira M, Rossato C, Nogueira Brandão W, Ghabdan Zanluqui N, Gomes de Oliveira L, Ayumi Nishiyama Mimura L, Braga Barros Silva M, Lúcia Garcia Calich V, Gil Nisenbaum M, Halpern S, Evangelista L, Maluf M, Perin P, Eduardo Czeresnia C, Schatzmann Peron JP. | 11/22/2021 |