Characterization of erythroferrone oligomerization and its impact on BMP antagonism. | Characterization of erythroferrone oligomerization and its impact on BMP antagonism. Mast JF, Leach EAE, Thompson TB., Free PMC Article | 02/6/2024 |
Characterization of erythroferrone structural domains relevant to its iron-regulatory function. | Characterization of erythroferrone structural domains relevant to its iron-regulatory function. Srole DN, Jung G, Waring AJ, Nemeth E, Ganz T., Free PMC Article | 01/11/2024 |
Placental Erythroferrone and Erythropoietin mRNA Expression is not Associated with Maternal or Neonatal Iron Status in Adolescents Carrying Singletons and Adult Women Carrying Multiples. | Placental Erythroferrone and Erythropoietin mRNA Expression is not Associated with Maternal or Neonatal Iron Status in Adolescents Carrying Singletons and Adult Women Carrying Multiples. Delaney KM, Barad A, Castillo LF, Hasund CM, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O'Brien KO., Free PMC Article | 07/12/2023 |
In Silico Pan-Cancer Analysis Reveals Prognostic Role of the Erythroferrone (ERFE) Gene in Human Malignancies. | In Silico Pan-Cancer Analysis Reveals Prognostic Role of the Erythroferrone (ERFE) Gene in Human Malignancies. Xu Q, Altrock E, Schmitt N, Streuer A, Rapp F, Nowak V, Obländer J, Weimer N, Palme I, Göl M, Hofmann WK, Nowak D, Riabov V., Free PMC Article | 01/28/2023 |
Plasma Complement C1q/tumor necrosis factor-related protein 15 concentration is associated with polycystic ovary syndrome. | Plasma Complement C1q/tumor necrosis factor-related protein 15 concentration is associated with polycystic ovary syndrome. Vatannejad A, Fadaei R, Salimi F, Fouani FZ, Habibi B, Shapourizadeh S, Eivazi S, Eivazi S, Sadeghi A, Moradi N., Free PMC Article | 07/2/2022 |
Serum erythroferrone levels during the first month of life in premature infants. | Serum erythroferrone levels during the first month of life in premature infants. Lenhartová N, Ochiai M, Sawano T, Yasuoka K, Fujiyoshi J, Inoue H, Ohga S. | 05/7/2022 |
Higher serum level of CTRP15 in patients with coronary artery disease is associated with disease severity, body mass index and insulin resistance. | Higher serum level of CTRP15 in patients with coronary artery disease is associated with disease severity, body mass index and insulin resistance. Shokoohi Nahrkhalaji A, Ahmadi R, Fadaei R, Panahi G, Razzaghi M, Fallah S. | 02/19/2022 |
Umbilical Cord Erythroferrone Is Inversely Associated with Hepcidin, but Does Not Capture the Most Variability in Iron Status of Neonates Born to Teens Carrying Singletons and Women Carrying Multiples. | Umbilical Cord Erythroferrone Is Inversely Associated with Hepcidin, but Does Not Capture the Most Variability in Iron Status of Neonates Born to Teens Carrying Singletons and Women Carrying Multiples. Delaney KM, Guillet R, Pressman EK, Ganz T, Nemeth E, O'Brien KO., Free PMC Article | 02/5/2022 |
The impacts of C1q/TNF-related protein-15 and adiponectin on Interleukin-6 and tumor necrosis factor-alpha in primary macrophages of patients with coronary artery diseases. | The impacts of C1q/TNF-related protein-15 and adiponectin on Interleukin-6 and tumor necrosis factor-α in primary macrophages of patients with coronary artery diseases. Ahmadi R, Fadaei R, Shokoohi Nahrkhalaji A, Panahi G, Fallah S. | 01/22/2022 |
Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone. | Differentiating iron-loading anemias using a newly developed and analytically validated ELISA for human serum erythroferrone. Diepeveen L, Roelofs R, Grebenchtchikov N, van Swelm R, Kautz L, Swinkels D., Free PMC Article | 11/13/2021 |
Erythroferrone structure, function, and physiology: Iron homeostasis and beyond. | Erythroferrone structure, function, and physiology: Iron homeostasis and beyond. Srole DN, Ganz T., Free PMC Article | 10/16/2021 |
Erythroferrone and hepcidin as mediators between erythropoiesis and iron metabolism during allogeneic hematopoietic stem cell transplant. | Erythroferrone and hepcidin as mediators between erythropoiesis and iron metabolism during allogeneic hematopoietic stem cell transplant. Pirotte M, Fillet M, Seidel L, Jaspers A, Baron F, Beguin Y., Free PMC Article | 10/2/2021 |
Association of decreased myonectin levels with metabolic and hormonal disturbance in polycystic ovary syndrome. | Association of decreased myonectin levels with metabolic and hormonal disturbance in polycystic ovary syndrome. Demir İ, Guler A. | 08/28/2021 |
High erythroferrone expression in CD71(+) erythroid progenitors predicts superior survival in myelodysplastic syndromes. | High erythroferrone expression in CD71(+) erythroid progenitors predicts superior survival in myelodysplastic syndromes. Riabov V, Mossner M, Stöhr A, Jann JC, Streuer A, Schmitt N, Knaflic A, Nowak V, Weimer N, Obländer J, Palme I, Schumann C, Baldus CD, Schulze TJ, Wuchter P, Röhl H, Jawhar A, Weiss C, Boch T, Metzgeroth G, Neumann M, Hofmann WK, Nolte F, Nowak D. | 08/14/2021 |
Disordered serum erythroferrone and hepcidin levels as indicators of the spontaneous abortion occurrence during early pregnancy in humans. | Disordered serum erythroferrone and hepcidin levels as indicators of the spontaneous abortion occurrence during early pregnancy in humans. Wei S, Liu W, Qi Y, Guo Y, Zhang S, Wang L, Zhuang T, Zhang N, Liu S. | 06/26/2021 |
Interplay of erythropoietin, fibroblast growth factor 23, and erythroferrone in patients with hereditary hemolytic anemia. | Interplay of erythropoietin, fibroblast growth factor 23, and erythroferrone in patients with hereditary hemolytic anemia. van Vuren AJ, Eisenga MF, van Straaten S, Glenthøj A, Gaillard CAJM, Bakker SJL, de Borst MH, van Wijk R, van Beers EJ., Free PMC Article | 06/19/2021 |
Implications of C1q/TNF-related protein superfamily in patients with coronary artery disease. | Implications of C1q/TNF-related protein superfamily in patients with coronary artery disease. Zhang Y, Liu C, Liu J, Guo R, Yan Z, Liu W, Lau WB, Jiao X, Cao J, Xu K, Jia Y, Ma X, Wang Y., Free PMC Article | 12/19/2020 |
The expression of the variant ERFE transcript that was restricted to SF3B1-mutated erythroblasts decreased in lenalidomide-responsive anemic patients, identifying variant ERFE as a specific biomarker of clonal erythropoiesis. | A variant erythroferrone disrupts iron homeostasis in SF3B1-mutated myelodysplastic syndrome. Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, Droin N, Cagnard N, Kaltenbach S, Winter S, Kubasch AS, Bouscary D, Santini V, Toma A, Hunault M, Stamatoullas A, Gyan E, Cluzeau T, Platzbecker U, Adès L, Puy H, Stern MH, Karim Z, Mayeux P, Nemeth E, Park S, Ganz T, Kautz L, Kosmider O, Fontenay M., Free PMC Article | 07/25/2020 |
A recurrent low-frequency variant, A260S, in the ERFE gene was found in 12.5% of congenital dyserythropoietic anemia type II patients with a severe phenotype. This variant leads to increased levels of ERFE, with subsequently marked impairment of iron regulation pathways at the hepatic level. It modified iron overload by impairing the BMP/SMAD pathway. | The BMP-SMAD pathway mediates the impaired hepatic iron metabolism associated with the ERFE-A260S variant. Andolfo I, Rosato BE, Marra R, De Rosa G, Manna F, Gambale A, Iolascon A, Russo R. | 03/28/2020 |
using the ERFE gene expression, combined with serum hepcidin estimation, can substantiate the role of estimated TS% as a promising tool in screening for iron overload in beta-TM patients. | Erythroferrone, the new iron regulator: evaluation of its levels in Egyptian patients with beta thalassemia. El-Gamal RAE, Abdel-Messih IY, Habashy DM, Zaiema SEG, Pessar SA. | 01/18/2020 |
serum ERFE levels acutely increase in response to EPO in the setting of normal or impaired kidney function | Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease. Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E., Free PMC Article | 07/20/2019 |
Serum CTRP15 concentrations were associated with the key components of MetS and insulin resistance. | Circulating C1q/TNF-related protein isoform 15 is a marker for the presence of metabolic syndrome. Mi Q, Li Y, Wang M, Yang G, Zhao X, Liu H, Zheng H, Li L. | 06/1/2019 |
From a clinical point of view, erythroferrone could become a useful biological marker of iron metabolism and a therapeutic target. [review] | [The role of erythroferrone in iron metabolism: From experimental results to pathogenesis]. Vallet N, Club du Globule Rouge et du Fer. | 10/27/2018 |
FAM132b expression is upregulated in Congenital Dyserythropoietic Anemia type II. | Increased levels of ERFE-encoding FAM132B in patients with congenital dyserythropoietic anemia type II. Russo R, Andolfo I, Manna F, De Rosa G, De Falco L, Gambale A, Bruno M, Mattè A, Ricchi P, Girelli D, De Franceschi L, Iolascon A. | 02/10/2018 |
Data suggest hepcidin is the master regulator of systemic iron homeostasis; hepcidin levels are suppressed when erythropoiesis is stimulated; the erythroid-derived hormone erythroferrone appears to be a convincing candidate for link between increased erythropoiesis and hepcidin suppression. [REVIEW] | Regulation of Hepcidin by Erythropoiesis: The Story So Far. Pasricha SR, McHugh K, Drakesmith H. | 07/22/2017 |