| Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex. | Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex.
Liu X, Blazejewski SM, Bennison SA, Toyo-Oka K., Free PMC Article | 10/9/2021 |
| GSTP1/2 are a critical regulators of hepatocyte proliferation in the initial phases of liver regeneration. | Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration.
Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, Aninat C, Loyer P, Morel F, Corlu A., Free PMC Article | 09/26/2015 |
| Matrin 3 interacts specifically with the heat shock proteins glucose-regulated protein 78, GRP75 and glutathione S-transferase pi isoform 2. | Matrin 3 co-immunoprecipitates with the heat shock proteins glucose-regulated protein 78 (GRP78), GRP75 and glutathione S-transferase π isoform 2 (GSTπ2) in thymoma cells.
Osman AM, van Loveren H. | 12/20/2014 |
| Apc(Min/+)Gstp1/p2(-/-) (Gstp-null Apc(Min)) mice had a 6-fold increase in colon adenoma incidence, and a 50-fold increase in colorectal adenoma multiplicity, relative to Gstp-wt Apc(Min). | Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi.
Ritchie KJ, Walsh S, Sansom OJ, Henderson CJ, Wolf CR., Free PMC Article | 09/13/2010 |
| GSTP protects against the endothelial dysfunction induced by tobacco smoke exposure and that this protection may be related to the detoxification of acrolein or other related cigarette smoke constituents. | Glutathione-S-transferase P protects against endothelial dysfunction induced by exposure to tobacco smoke.
Conklin DJ, Haberzettl P, Prough RA, Bhatnagar A., Free PMC Article | 01/21/2010 |
| The downregulation of Gstp2 may induce an increase of oxidative damage in the pyramidal cells of the CA1 and CA3 regions and granular layer of the dentate gyrus, leading to structural and functional damage. | Chronic restraint stress decreases the expression of glutathione S-transferase pi2 in the mouse hippocampus.
Ejchel-Cohen TF, Wood GE, Wang JF, Barlow K, Nobrega JN, S McEwen B, Trevor Young L. | 01/21/2010 |
| The glutathione S-transferase, pi 2 was represented by two EST clones with similar levels of downregulation. | Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins.
Bakin AV, Stourman NV, Sekhar KR, Rinehart C, Yan X, Meredith MJ, Arteaga CL, Freeman ML. | 01/21/2010 |
| critical role of allyl groups and disulfide chain in induction by diallyl disulfide, a naturally occurring chemopreventive agent in garlic | Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic.
Bose C, Guo J, Zimniak L, Srivastava SK, Singh SP, Zimniak P, Singh SV. | 01/21/2010 |
| These results suggest that GSTpi may play a protective role in the development of spontaneous tumors. | Influence of glutathione S-transferase pi and p53 expression on tumor frequency and spectrum in mice.
Gate L, Majumdar RS, Lunk A, Tew KD. | 01/21/2010 |
| role as a direct inhibitor of JNK in vivo and in regulating the constitutive expression of specific downstream molecular targets of the JNK signaling pathway | Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi.
Elsby R, Kitteringham NR, Goldring CE, Lovatt CA, Chamberlain M, Henderson CJ, Wolf CR, Park BK. | 01/21/2010 |
| Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells. | Nrf2 transactivator-independent GSTP1-1 expression in "GSTP1-1 positive" single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells.
Satoh K, Itoh K, Yamamoto M, Tanaka M, Hayakari M, Ookawa K, Yamazaki T, Sato T, Tsuchida S, Hatayama I. | 01/21/2010 |