| Connexins 30 and 43 expression changes in relation to age-related hearing loss. | Connexins 30 and 43 expression changes in relation to age-related hearing loss.
Pineros J, Zhu X, Ding B, Frisina RD., | 08/2/2024 |
| Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice. | Levels and Modifications of Both Lens Fiber Cell Connexins Are Affected in Connexin Mutant Mice.
Jara O, Minogue PJ, Berthoud VM, Beyer EC., Free PMC Article | 10/8/2022 |
| Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens? | Do Connexin Mutants Cause Cataracts by Perturbing Glutathione Levels and Redox Metabolism in the Lens?
Jara O, Minogue PJ, Berthoud VM, Beyer EC., Free PMC Article | 09/11/2021 |
| that expression and phosphorylation of connexin 46 and connexin 45 are complementary in seminiferous tubules | Complementary expression and phosphorylation of Cx46 and Cx50 during development and following gene deletion in mouse and in normal and orchitic mink testes.
Pelletier RM, Akpovi CD, Chen L, Kumar NM, Vitale ML., Free PMC Article | 10/17/2015 |
| The localization and sizes of Cx50 gap junction plaques in DKO fibers were unaffected, suggesting that Cx46 and Cx50 form homomeric channels | Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells.
Cheng C, Nowak RB, Gao J, Sun X, Biswas SK, Lo WK, Mathias RT, Fowler VM., Free PMC Article | 07/25/2015 |
| Data indicate that connexin 46 (cx46) is essential for the maintenance of adequate levels of glutathione (GSH) in the lens nucleus. | Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleus.
Slavi N, Rubinos C, Li L, Sellitto C, White TW, Mathias R, Srinivas M., Free PMC Article | 02/14/2015 |
| Cx46 was severely reduced in both heterozygous and homozygous Cx46fs380 lenses at 1 month of age, whereas immunoreactive connexin50 (Cx50) was moderately decreased. | Connexin46fs380 causes progressive cataracts.
Berthoud VM, Minogue PJ, Yu H, Snabb JI, Beyer EC., Free PMC Article | 12/27/2014 |
| Results suggest that Cx46 hemichannels may contribute to the sodium leak conductance in lens fiber cells. | Cx46 hemichannels contribute to the sodium leak conductance in lens fiber cells.
Ebihara L, Korzyukov Y, Kothari S, Tong JJ., Free PMC Article | 04/26/2014 |
| Data show that Ca(V) 1.2 and 1.3 channels are expressed in lens, regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins 50 and 46. | L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins.
Maddala R, Nagendran T, de Ridder GG, Schey KL, Rao PV., Free PMC Article | 01/11/2014 |
| These results provide further evidence that Cx43 and Cx46 form both heterotypic and heteromeric channels when co-expressed. | Functional analysis of hemichannels and gap-junctional channels formed by connexins 43 and 46.
Hoang QV, Qian H, Ripps H., Free PMC Article | 11/13/2010 |
| There were no observed changes in gene expression as a result of the lack of alpha3Cx46 in the different mouse strains. | Global gene expression analysis of lenses from different mouse strains and in the alpha3Cx46 knockout mouse.
Tang Y, Crowley TE, Kumar NM., Free PMC Article | 03/15/2010 |
| Results indicates connexin 46 expressed alone are recruited into different lipid environments and interaction of connexins and MP26 contributes to the overall organization of the fiber cells. | Structural and immunocytochemical alterations in eye lens fiber cells from Cx46 and Cx50 knockout mice.
Dunia I, Cibert C, Gong X, Xia CH, Recouvreur M, Levy E, Kumar N, Bloemendal H, Benedetti EL. | 01/21/2010 |
| Transient decrease in gap junction expression during compensatory renal growth in mice | Transient decrease in gap junction expression during compensatory renal growth in mice.
Li S, Nomata K, Hayashi T, Noguchi M, Kanda S, Kanetake H. | 01/21/2010 |
| nonspecific restoration of communication by Cx46 maintained differentiation of lens cells | Unique and redundant connexin contributions to lens development.
White TW. | 01/21/2010 |