| The effects of ROMO1 on cervical cancer progression. | The effects of ROMO1 on cervical cancer progression.
Tsoneva E, Dimitrova PD, Metodiev M, Shivarov V, Vasileva-Slaveva M, Yordanov A. | 08/20/2023 |
| Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer. | Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer.
Chen WY, Thuy Dung PV, Yeh HL, Chen WH, Jiang KC, Li HR, Chen ZQ, Hsiao M, Huang J, Wen YC, Liu YN., Free PMC Article | 05/28/2023 |
| Network models of prostate cancer immune microenvironments identify ROMO1 as heterogeneity and prognostic marker. | Network models of prostate cancer immune microenvironments identify ROMO1 as heterogeneity and prognostic marker.
Wang L, Liu X, Liu Z, Wang Y, Fan M, Yin J, Zhang Y, Ma Y, Luo J, Li R, Zhao X, Zhang P, Zhao L, Fan J, Chen Y, Lu W, Song X., Free PMC Article | 02/26/2022 |
| Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer. | Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer.
Ghasemi H, Amini MA, Pegah A, Azizi E, Tayebinia H, Khanverdilou S, Mousavibahar SH, Alizamir A., Free PMC Article | 05/29/2021 |
| The C allele of the reactive oxygen species modulator 1 (ROMO1) polymorphism rs6060566 is a biomarker predicting coronary artery stenosis in Slovenian subjects with type 2 diabetes mellitus. | The C allele of the reactive oxygen species modulator 1 (ROMO1) polymorphism rs6060566 is a biomarker predicting coronary artery stenosis in Slovenian subjects with type 2 diabetes mellitus.
Tibaut M, Mankoč Ramuš S, Petrovič D., Free PMC Article | 05/8/2021 |
| Overexpression of ROMO1 and OMA1 are Potentially Biomarkers and Predict Unfavorable Prognosis in Gastric Cancer. | Overexpression of ROMO1 and OMA1 are Potentially Biomarkers and Predict Unfavorable Prognosis in Gastric Cancer.
Amini MA, Karimi J, Khodadadi I, Tavilani H, Talebi SS, Afshar B. | 03/27/2021 |
| Long noncoding RNA LINC00319 regulates ROMO1 expression and promotes bladder cancer progression via miR-4492/ROMO1 axis. | Long noncoding RNA LINC00319 regulates ROMO1 expression and promotes bladder cancer progression via miR-4492/ROMO1 axis.
Yang Y, Zhang F, Huang H, Xie Z, Huang W, Xie H, Wang F. | 02/6/2021 |
| Reactive oxygen species modulator 1 expression predicts lymph node metastasis and survival in early-stage non-small cell lung cancer. | Reactive oxygen species modulator 1 expression predicts lymph node metastasis and survival in early-stage non-small cell lung cancer.
Kim T, Cha YJ, Park JH, Kim A, Choi YJ, Park HJ., Free PMC Article | 01/16/2021 |
| Clinical value of combined detection of reactive oxygen species modulator 1 and adenosine deaminase in pleural effusion in the identification of NSCLC associated malignant pleural effusion. | Clinical value of combined detection of reactive oxygen species modulator 1 and adenosine deaminase in pleural effusion in the identification of NSCLC associated malignant pleural effusion.
Zhang F, Wang J, Fu J, Hu L, Zheng X, Wang Y, Chen B., Free PMC Article | 12/19/2020 |
| serum Romo1 levels increase in COPD patients and these levels are associated with lung function, inflammation, and oxidative stress in COPD. | Increased Serum Romo1 Was Correlated with Lung Function, Inflammation, and Oxidative Stress in Chronic Obstructive Pulmonary Disease.
Ye L, Mao S, Fang S, Zhang J, Tan Y, Gu W. | 02/22/2020 |
| These results showed that mitochondrial reactiveo xygen species (mtROS) production was also enhanced by the SRA dependent ERK activation through upregulation and activation of reactive oxygen species modulator 1(ROMO1), a mitochondrial membrane protein and a key mediator of mtROS. | Stimulation of the class-A scavenger receptor induces neutrophil extracellular traps (NETs) by ERK dependent NOX2 and ROMO1 activation.
Zhu Y, Yang Y, Li F, Fan S, Chen X, Lu Y, Wei Y, Chen Q, Xia L, Tang J, Huang Q, Zhu Q, Zheng J, Liu X. | 01/18/2020 |
| in the absence of ROMO1, mitochondria lose the inner membrane YME1L protease, which participates in OPA1 processing and ROMO1 turnover. While ROMO1 is dispensable for general protein import along the presequence pathway, we show that it participates in the dynamics of TIM21 during respiratory chain biogenesis and is specifically required for import of YME1L. | ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.
Richter F, Dennerlein S, Nikolov M, Jans DC, Naumenko N, Aich A, MacVicar T, Linden A, Jakobs S, Urlaub H, Langer T, Rehling P., Free PMC Article | 12/14/2019 |
| Romo1 establishes a new category of viroporin-like nonselective cation channel in eukaryotes. | Romo1 is a mitochondrial nonselective cation channel with viroporin-like characteristics.
Lee GY, You DG, Lee HR, Hwang SW, Lee CJ, Yoo YD., Free PMC Article | 05/18/2019 |
| the increase of serum Romo1 in obstructive sleep apnea syndrome (OSAS) patients was positively correlated with disease severity; serum Romo1 may be an important parameter for monitoring the severity of OSAS and treatment efficiency | Serum Romo1 is significantly associated with disease severity in patients with obstructive sleep apnea syndrome.
Ye L, Qian Y, Li Q, Fang S, Yang Z, Tan Y, Gu W. | 05/4/2019 |
| Romo1 overexpression was associated with poor response to treatment and shorter survival in advanced NSCLC patients treated with platinum-based chemotherapy. Romo1 could be a potential adverse predictive marker in this setting. | Reactive Oxygen Species Modulator 1 (Romo1) Predicts Poor Outcomes in Advanced Non-small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy.
Lee SH, Choi SI, Lee JS, Kim CH, Jung WJ, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Lee SY, Shin C, Shim JJ, Kang KH, In KH., Free PMC Article | 02/10/2018 |
| Increased Romo1 expression was found to be associated with high lymph node ratio. Cancer invasiveness appeared to be a key reason for the poor survival related to highly expressed Romo1 | Reactive oxygen species modulator-1 (Romo1) predicts unfavorable prognosis in colorectal cancer patients.
Kim HJ, Jo MJ, Kim BR, Kim JL, Jeong YA, Na YJ, Park SH, Lee SY, Lee DH, Lee HS, Kim BH, Lee SI, Min BW, Yoo YD, Oh SC., Free PMC Article | 09/16/2017 |
| the diagnostic sensitivity and specificity of serum reactive oxygen species modulator 1 were only 41.38% and 86.21%, respectively, with the cutoff value of 27.22 ng/mL. The sensitivity and specificity of pleural fluid carcinoembryonic antigen were 69.23% and 88.00%, respectively, at the cutoff value of 3.05 ng/mL, while serum carcinoembryonic antigen were 80.77% and 72.00% at the cutoff value of 2.60 ng/mL. | Reactive oxygen species modulator 1, a novel protein, combined with carcinoembryonic antigen in differentiating malignant from benign pleural effusion.
Chen X, Zhang N, Dong J, Sun G. | 06/10/2017 |
| elevated in pleural effusion when lung cancer present | Reactive oxygen species modulator 1 (Romo1) as a novel diagnostic marker for lung cancer-related malignant effusion.
Lee SH, Park MJ, Choi SI, Lee EJ, Lee SY, In KH., Free PMC Article | 02/25/2017 |
| The rs6060566 polymorphism of the Romo-1 gene was found to be an independent risk factor for DR in Caucasians with T2DM. | The rs6060566 of the reactive oxygen species modulator 1 (Romo-1) gene affects Romo-1 expression and the development of diabetic retinopathy in Caucasians with type 2 diabetes.
Petrovic MG, Kruzliak P, Petrovic D. | 08/27/2016 |
| Genetic polymorphisms of Romo1 gene were associated with significant risk of gastric cancer. | Association of Romo1 gene genetic polymorphisms with risk of gastric cancer in northwestern Chinese population.
Wu H, Gu YH, Wei L, Guo TK, Zhao Y, Su G, Li J, Xie XD. | 03/5/2016 |
| These results demonstrate that tumor cell invasion in response to oxidative stress is associated with Romo1 expression and the NF-kappaB signaling pathway. | Romo1 and the NF-κB pathway are involved in oxidative stress-induced tumor cell invasion.
Lee S, Park YH, Chung JS, Yoo YD. | 02/6/2016 |
| Results demonstrate that expression of Romo1 is frequently upregulated in human glioblastomas and its elevation promotes malignant tumor progression by promoting cell cycle progression and by enhancing tumorigenicity | Romo1 is associated with ROS production and cellular growth in human gliomas.
Yu MO, Song NH, Park KJ, Park DH, Kim SH, Chae YS, Chung YG, Chi SG, Kang SH. | 09/26/2015 |
| Increased Romo1 expression in surgically resected NSCLC was found to be significantly associated with early recurrence and poor survival. Romo1 overexpression could be a potential adverse prognostic marker in this setting. | Reactive oxygen species modulator 1 (Romo1) overexpression is an independent predictor of poor survival in NSCLC patients who undergo surgical resection.
Lee SH, Min JW, Lee JS, Kim CH, Yoo YD, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Lee SY, Shin C, Shim JJ, Kang KH, In KH. | 08/22/2015 |
| Serum Romo1 discriminated NSCLC patients from the population without cancer with considerable sensitivity and specificity. Serum Romo1 could be a potential diagnostic biomarker for NSCLC. | Serum reactive oxygen species modulator 1 (Romo1) as a potential diagnostic biomarker for non-small cell lung cancer.
Lee SH, Lee JS, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Lee SY, Shin C, Shim JJ, Kang KH, In KH. | 07/25/2015 |
| High ROMO1 expression is associated with Fanconi anemia. | ROMO1 regulates RedOx states and serves as an inducer of NF-κB-driven EMT factors in Fanconi anemia.
Shyamsunder P, Verma RS, Lyakhovich A. | 05/23/2015 |