| A susceptibility gene signature for ERBB2-driven mammary tumour development and metastasis in collaborative cross mice. | A susceptibility gene signature for ERBB2-driven mammary tumour development and metastasis in collaborative cross mice.
Yang H, Wang X, Blanco-Gómez A, He L, García-Sancha N, Corchado-Cobos R, Pérez-Baena MJ, Jiménez-Navas A, Wang P, Inman JL, Snijders AM, Threadgill DW, Balmain A, Chang H, Perez-Losada J, Mao JH., Free PMC Article | 09/25/2024 |
| ERBB2 Targeting Reveals a Significant Suppression of Tumorigenesis in Murine Endometrial Cancer with Pten Mutation. | ERBB2 Targeting Reveals a Significant Suppression of Tumorigenesis in Murine Endometrial Cancer with Pten Mutation.
Dunston K, Hunter MI, Johannesen E, Jung JS, Kim TH, Yoo JY, Jeong JW. | 09/9/2024 |
| EGFR and HER-2 oncogenes expression in an experimental model of two-stage chemically induced carcinogenesis in mouse skin. | EGFR and HER-2 oncogenes expression in an experimental model of two-stage chemically induced carcinogenesis in mouse skin.
Diamantopoulou S, Yapijakis C, Papakosta V, Ebeling M, Lazaris AC, Derka S, Vylliotis A, Diamantopoulos P, Vairaktari G, Vassiliou S. | 05/20/2024 |
| HER2 phosphorylation induced by TGF-beta promotes mammary morphogenesis and breast cancer progression. | HER2 phosphorylation induced by TGF-β promotes mammary morphogenesis and breast cancer progression.
Shi Q, Huang F, Wang Y, Liu H, Deng H, Chen YG., Free PMC Article | 02/28/2024 |
| HER2Delta16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer. | HER2Δ16 Engages ENPP1 to Promote an Immune-Cold Microenvironment in Breast Cancer.
Attalla SS, Boucher J, Proud H, Taifour T, Zuo D, Sanguin-Gendreau V, Ling C, Johnson G, Li V, Luo RB, Kuasne H, Papavasiliou V, Walsh LA, Barok M, Joensuu H, Park M, Roux PP, Muller WJ. | 09/6/2023 |
| Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential. | Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential.
Cordero A, Santamaría PG, González-Suárez E., Free PMC Article | 06/23/2023 |
| Loss of MIG-6 results in endometrial progesterone resistance via ERBB2. | Loss of MIG-6 results in endometrial progesterone resistance via ERBB2.
Yoo JY, Kim TH, Shin JH, Marquardt RM, Müller U, Fazleabas AT, Young SL, Lessey BA, Yoon HG, Jeong JW., Free PMC Article | 04/23/2022 |
| Smad7 effects on TGF-beta and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. | Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure.
Humeres C, Shinde AV, Hanna A, Alex L, Hernández SC, Li R, Chen B, Conway SJ, Frangogiannis NG., Free PMC Article | 04/2/2022 |
| HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium. | HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium.
Murray E, Cheng X, Krishna A, Jin X, Ohara TE, Stappenbeck TS, Bose R., Free PMC Article | 03/12/2022 |
| Reproductive history determines Erbb2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model. | Reproductive history determines Erbb2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model.
Ordonez LD, Melchor L, Greenow KR, Kendrick H, Tornillo G, Bradford J, Giles P, Smalley MJ., Free PMC Article | 02/26/2022 |
| HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase. | HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase.
Ginzel JD, Acharya CR, Lubkov V, Mori H, Boone PG, Rochelle LK, Roberts WL, Everitt JI, Hartman ZC, Crosby EJ, Barak LS, Caron MG, Chen JQ, Hubbard NE, Cardiff RD, Borowsky AD, Lyerly HK, Snyder JC., Free PMC Article | 02/19/2022 |
| Dendritic Cells Pulsed with Cytokine-Adjuvanted Tumor Membrane Vesicles Inhibit Tumor Growth in HER2-Positive and Triple Negative Breast Cancer Models. | Dendritic Cells Pulsed with Cytokine-Adjuvanted Tumor Membrane Vesicles Inhibit Tumor Growth in HER2-Positive and Triple Negative Breast Cancer Models.
Munoz LE, Monterroza L, Bommireddy R, Shafizadeh Y, Pack CD, Ramachandiran S, Reddy SJC, Selvaraj P., Free PMC Article | 09/25/2021 |
| Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach. | Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach.
Atalay Şahar E, Döşkaya M, Karakavuk M, Can H, Gül A, Gürüz AY, Değirmenci Döşkaya A, Yeniay L. | 09/4/2021 |
| NRG/ErbB signaling regulates neonatal muscle growth but not neuromuscular contractures in neonatal brachial plexus injury. | NRG/ErbB signaling regulates neonatal muscle growth but not neuromuscular contractures in neonatal brachial plexus injury.
Ho BL, Goh Q, Nikolaou S, Hu L, Shay-Winkler K, Cornwall R., Free PMC Article | 07/31/2021 |
| Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice. | Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice.
Hedegger K, Algül H, Lesina M, Blutke A, Schmid RM, Schneider MR, Dahlhoff M., Free PMC Article | 07/3/2021 |
| ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration. | ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration.
Aharonov A, Shakked A, Umansky KB, Savidor A, Genzelinakh A, Kain D, Lendengolts D, Revach OY, Morikawa Y, Dong J, Levin Y, Geiger B, Martin JF, Tzahor E. | 02/2/2021 |
| Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma. | Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma.
Meyers N, Gérard C, Lemaigre FP, Jacquemin P., Free PMC Article | 12/19/2020 |
| Upregulation of HER2 in tubular epithelial cell drives fibroblast activation and renal fibrosis. | Upregulation of HER2 in tubular epithelial cell drives fibroblast activation and renal fibrosis.
Li H, Shao F, Qian B, Sun Y, Huang Z, Ding Z, Dong L, Chen J, Zhang J, Zang Y. | 10/24/2020 |
| Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells. | Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells.
Candas-Green D, Xie B, Huang J, Fan M, Wang A, Menaa C, Zhang Y, Zhang L, Jing D, Azghadi S, Zhou W, Liu L, Jiang N, Li T, Gao T, Sweeney C, Shen R, Lin TY, Pan CX, Ozpiskin OM, Woloschak G, Grdina DJ, Vaughan AT, Wang JM, Xia S, Monjazeb AM, Murphy WJ, Sun LQ, Chen HW, Lam KS, Weichselbaum RR, Li JJ., Free PMC Article | 09/26/2020 |
| Regulation of the translation activity of antigen-specific mRNA is responsible for antigen loss and tumor immune escape in a HER2-expressing tumor model. | Regulation of the translation activity of antigen-specific mRNA is responsible for antigen loss and tumor immune escape in a HER2-expressing tumor model.
Han BS, Ji S, Woo S, Lee JH, Sin JI., Free PMC Article | 09/12/2020 |
| A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure. | A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.
Shawer H, Aiyelaagbe E, Clowes C, Lean SC, Lu Y, Kadler KE, Kerby A, Dilworth MR, Hentges KE, Heazell AEP., Free PMC Article | 08/29/2020 |
| Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. | Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
Honkoop H, de Bakker DE, Aharonov A, Kruse F, Shakked A, Nguyen PD, de Heus C, Garric L, Muraro MJ, Shoffner A, Tessadori F, Peterson JC, Noort W, Bertozzi A, Weidinger G, Posthuma G, Grün D, van der Laarse WJ, Klumperman J, Jaspers RT, Poss KD, van Oudenaarden A, Tzahor E, Bakkers J., Free PMC Article | 06/20/2020 |
| Her2, MUC1, and a novel fusion structure were expressed in the seeds and hairy roots of transgenic plants appropriately. | Immunogenicity Evaluation of Recombinant Edible Vaccine Candidate Containing HER2-MUC1 against Breast Cancer.
Mehrab Mohseni M, Amani J, Fasihi Ramandi M, Mahjoubi F, Jafaria M, Salmanian AH. | 05/30/2020 |
| For the development of new therapeutics against HER2-overexpressing cancers. | Immunological Responses against HER2-targeted Idarubicin-ZHER2 Conjugate in BALB/c Mice.
Siavoshinia L, Jamalan M, Zeinali M, Mohammadzadeh G. | 05/30/2020 |
| Male FBV/N mice with intramuscularly transplanted HER2-positive mammary gland tumor from a female mouse of the same strain have been given toremifene. | Enchancement of Toremifene Anti-Tumor Action by Metformin and Unusual Side Effect of Toremifene in Male Transgenic Mice with HER2-Positive Breast Tumor.
Stukov AN, Osipov MA, Semiglazova TY, Filatova LV, Alexandrov VA, Bespalov VG, Semenov AL, Tyndyk ML, Yurova MN, Panchenko AV, Baranenko DA. | 04/11/2020 |