| Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood. | Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood.
Bertrand-Gaday C, Letheule M, Blanchet E, Vernus B, Pessemesse L, Bonnet-Garnier A, Bonnieu A, Casas F., Free PMC Article | 02/27/2021 |
| Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells. | Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells.
Ranasinghe ADCU, Lee DD, Schwarz MA., Free PMC Article | 01/9/2021 |
| The Role of the AIMP1 Pathway in Diabetic Retinopathy: AIMP1-Targeted Intervention Study in Diabetic Retinopathy. | The Role of the AIMP1 Pathway in Diabetic Retinopathy: AIMP1-Targeted Intervention Study in Diabetic Retinopathy.
Zou C, Gu C, Zhao M, Zhu D, Wang N, Yu J, Yao Y, Chen Y, Shi M, Gu Q, Qian Y, Qiu Q, Zheng Z. | 01/9/2021 |
| Influence of aminoacyl-tRNA synthetase complex-interacting multifunctional protein 1 on epithelial differentiation and organization during lung development. | Influence of aminoacyl-tRNA synthetase complex-interacting multifunctional protein 1 on epithelial differentiation and organization during lung development.
Lee DD, Hochstetler A, Sah E, Xu H, Lowe CW, Santiaguel S, Thornton JL, Pajakowski A, Schwarz MA., Free PMC Article | 11/21/2020 |
| AIMP1 regulates TCR signaling and induces differentiation of regulatory T cells by interfering with lipid raft association. | AIMP1 regulates TCR signaling and induces differentiation of regulatory T cells by interfering with lipid raft association.
Kim MS, Lee A, Cho D, Kim TS. | 06/20/2020 |
| results show that AIMP1 induces antitumor responses by NK cell activation mainly via macrophages | Aminoacyl tRNA Synthetase--Interacting Multifunctional Protein 1 Activates NK Cells via Macrophages In Vitro and In Vivo.
Kim MS, Song JH, Cohen EP, Cho D, Kim TS. | 09/23/2017 |
| Blockade of EMAP II induces angiogenesis and improves cardiac function following chronic myocardial infarction. | Blockade of EMAP II protects cardiac function after chronic myocardial infarction by inducing angiogenesis.
Yuan C, Yan L, Solanki P, Vatner SF, Vatner DE, Schwarz MA., Free PMC Article | 09/26/2015 |
| findings indicate that Aimp1 might act as an important regulator to remodel the uterine endometrium and its expression might be regulated by estrogen during the estrous cycle. | The expression of aminoacyl-tRNA-synthetase-interacting multifunctional protein-1 (Aimp1) is regulated by estrogen in the mouse uterus.
Jeong JH, Park M, Park M, Lim EJ, Kim HR, Song H, Park SG, Choi EJ, Hong KH, Lee DR, Ko JJ, Choi Y. | 08/8/2015 |
| our results show that AIMP1 acts as a novel B cell-activating factor | Aminoacyl tRNA Synthetase-Interacting Multifunctional Protein 1 Acts as a Novel B Cell-Activating Factor In Vitro and In Vivo.
Kim MS, Kim TS. | 07/25/2015 |
| The data showed that AIMP1 is a negative regulator of TH2 immune responses, mainly via CD4+ T cells. | AIMP1 deficiency enhances airway hyperreactivity in mice via increased TH2 immune responses.
Hong HJ, Kim E, Jung MY, Kim S, Kim TS. | 07/21/2012 |
| In dendritic cells, AIMP1 enhances toll-like receptor 2 (TLR2)-mediated immune responses via the up-regulation of TLR2 expression. | Enhancement of toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells.
Kim E, Hong HJ, Cho D, Han JM, Kim S, Kim TS., Free PMC Article | 10/15/2011 |
| Lung-specific overexpression of EMAPII in mice caused simplification of alveolar structures, apoptosis, & macrophage accumulation. Smoking-induced upregulation involved an apoptosis-dependent feed-forward loop. | Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.
Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, Twigg HL 3rd, Presson RG, Sethi S, Petrache I., Free PMC Article | 08/20/2011 |
| Mice lacking MSC p43 exhibited axon degeneration in motor neurons, defective neuromuscular junctions, muscular atrophy, and motor dysfunction. Furthermore, MSC p43 depletion in mice caused disorganization of the axonal neurofilament network. | MSC p43 required for axonal development in motor neurons.
Zhu X, Liu Y, Yin Y, Shao A, Zhang B, Kim S, Zhou J., Free PMC Article | 01/21/2010 |
| important yet unrecognized roles of EMAP-II and adventitial inflammation in neointima formation. | EMAP-II downregulation contributes to the beneficial effects of rapamycin after vascular injury.
Nührenberg TG, Langwieser N, Schwarz JB, Hou Y, Frank P, Sorge F, Matschurat S, Seidl S, Kastrati A, Schömig A, Clauss MA, Zohlnhöfer D. | 01/21/2010 |
| AIMP1 induces the maturation and activation of dendritic cells, which skew the immune response toward a T helper type 1 (Th1) cell response. | AIMP1/p43 protein induces the maturation of bone marrow-derived dendritic cells with T helper type 1-polarizing ability.
Kim E, Kim SH, Kim S, Cho D, Kim TS. | 01/21/2010 |
| AIMP1 negatively regulates TGF-beta signaling via stabilization of Smurf2. | AIMP1/p43 downregulates TGF-beta signaling via stabilization of smurf2.
Lee YS, Han JM, Son SH, Choi JW, Jeon EJ, Bae SC, Park YI, Kim S. | 01/21/2010 |
| AIMP1 plays a glucagon-like role in glucose homeostasis. | Hormonal activity of AIMP1/p43 for glucose homeostasis.
Park SG, Kang YS, Kim JY, Lee CS, Ko YG, Lee WJ, Lee KU, Yeom YI, Kim S., Free PMC Article | 01/21/2010 |
| Results suggest that AIMP1 acts as a regulator of the ER retention of gp96 and provide a new perspective of the regulatory mechanism underlying immune stimulation by gp96. | Aminoacyl-tRNA synthetase-interacting multifunctional protein 1/p43 controls endoplasmic reticulum retention of heat shock protein gp96: its pathological implications in lupus-like autoimmune diseases.
Han JM, Park SG, Liu B, Park BJ, Kim JY, Jin CH, Song YW, Li Z, Kim S., Free PMC Article | 01/21/2010 |