| Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage abeta pathology. | Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology.
Yook Y, Lee KY, Kim E, Lizarazo S, Yu X, Tsai NP., Free PMC Article | 03/15/2024 |
| Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment. | Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment.
Fadahunsi N, Petersen J, Metz S, Jakobsen A, Vad Mathiesen C, Silke Buch-Rasmussen A, Kurgan N, Kjærgaard Larsen J, Andersen RC, Topilko T, Svendsen C, Apuschkin M, Skovbjerg G, Hendrik Schmidt J, Houser G, Elgaard Jager S, Bach A, Deshmukh AS, Kilpeläinen TO, Strømgaard K, Madsen KL, Clemmensen C., Free PMC Article | 03/7/2024 |
| A PSD-95 peptidomimetic mitigates neurological deficits in a mouse model of Angelman syndrome. | A PSD-95 peptidomimetic mitigates neurological deficits in a mouse model of Angelman syndrome.
Lau KA, Yang X, Rioult-Pedotti MS, Tang S, Appleman M, Zhang J, Tian Y, Marino C, Yao M, Jiang Q, Tsuda AC, Huang YA, Cao C, Marshall J. | 09/21/2023 |
| Downregulation of Preso protects against ischemic/reperfusion-mediated neuronal injury through regulating PSD95-nNOS/YAP pathways. | Downregulation of Preso protects against ischemic/reperfusion-mediated neuronal injury through regulating PSD95-nNOS/YAP pathways.
Chen R, Qian L, Fu J, Qin J, Chen X, Xu X. | 08/25/2023 |
| Environmental enrichment alters LPS-induced changes in BDNF and PSD-95 expressions during puberty. | Environmental enrichment alters LPS-induced changes in BDNF and PSD-95 expressions during puberty.
Murack M, Smith KB, Traynor OH, Pirwani AF, Gostlin SK, Mohamed T, Tata DA, Messier C, Ismail N. | 03/20/2023 |
| Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice via Canonical NO-mediated Protein Kinase-G Signaling. | Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice via Canonical NO-mediated Protein Kinase-G Signaling.
Agarwal S, Schaefer ML, Krall C, Johns RA., Free PMC Article | 07/23/2022 |
| POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function. | POSH regulates assembly of the NMDAR/PSD-95/Shank complex and synaptic function.
Yao M, Meng M, Yang X, Wang S, Zhang H, Zhang F, Shi L, Zhang Y, Zhang X, Xu Z. | 04/23/2022 |
| PSD-95 protects synapses from beta-amyloid. | PSD-95 protects synapses from β-amyloid.
Dore K, Carrico Z, Alfonso S, Marino M, Koymans K, Kessels HW, Malinow R., Free PMC Article | 02/12/2022 |
| Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits. | Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits.
Zhou Y, Lu H, Liu Y, Zhao Z, Zhang Q, Xue C, Zou Y, Cao Z, Luo W., Free PMC Article | 02/5/2022 |
| Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway. | Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway.
Karadayian AG, Bustamante J, Lores-Arnaiz S. | 01/22/2022 |
| Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density. | Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density.
Zarate N, Intihar TA, Yu D, Sawyer J, Tsai W, Syed M, Carlson L, Gomez-Pastor R., Free PMC Article | 01/8/2022 |
| Disrupting nNOS-PSD95 Interaction Improves Neurological and Cognitive Recoveries after Traumatic Brain Injury. | Disrupting nNOS-PSD95 Interaction Improves Neurological and Cognitive Recoveries after Traumatic Brain Injury.
Qu W, Liu NK, Wu X, Wang Y, Xia Y, Sun Y, Lai Y, Li R, Shekhar A, Xu XM., Free PMC Article | 12/18/2021 |
| MAGUKs are essential, but redundant, in long-term potentiation. | MAGUKs are essential, but redundant, in long-term potentiation.
Chen X, Fukata Y, Fukata M, Nicoll RA., Free PMC Article | 12/4/2021 |
| PSD-95 protects the pancreas against pathological damage through p38 MAPK signaling pathway in acute pancreatitis. | PSD-95 protects the pancreas against pathological damage through p38 MAPK signaling pathway in acute pancreatitis.
Guo Y, Hu W, Wang X, Li C, Cui T, Liu R, He J, Yin C., Free PMC Article | 11/22/2021 |
| PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex. | PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex.
McEachern EP, Coley AA, Yang SS, Gao WJ., Free PMC Article | 08/28/2021 |
| Spine dynamics of PSD-95-deficient neurons in the visual cortex link silent synapses to structural cortical plasticity. | Spine dynamics of PSD-95-deficient neurons in the visual cortex link silent synapses to structural cortical plasticity.
Yusifov R, Tippmann A, Staiger JF, Schlüter OM, Löwel S., Free PMC Article | 08/21/2021 |
| A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke. | A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke.
Ayuso-Dolado S, Esteban-Ortega GM, Vidaurre ÓG, Díaz-Guerra M., Free PMC Article | 08/7/2021 |
| A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and alpha2-containning GABAARs. | A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABA(A)Rs.
Li J, Zhang L, Xu C, Shen YY, Lin YH, Zhang Y, Wu HY, Chang L, Zhang YD, Chen R, Zhang ZP, Luo CX, Li F, Zhu DY., Free PMC Article | 07/31/2021 |
| PSD-95 in CA1 Area Regulates Spatial Choice Depending on Age. | PSD-95 in CA1 Area Regulates Spatial Choice Depending on Age.
Cały A, Śliwińska MA, Ziółkowska M, Łukasiewicz K, Pagano R, Dzik JM, Kalita K, Bernaś T, Stewart MG, Giese KP, Radwanska K., Free PMC Article | 06/12/2021 |
| NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95. | NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95.
Compans B, Camus C, Kallergi E, Sposini S, Martineau M, Butler C, Kechkar A, Klaassen RV, Retailleau N, Sejnowski TJ, Smit AB, Sibarita JB, Bartol TM Jr, Perrais D, Nikoletopoulou V, Choquet D, Hosy E., Free PMC Article | 06/5/2021 |
| PSD-95 deficiency disrupts PFC-associated function and behavior during neurodevelopment. | PSD-95 deficiency disrupts PFC-associated function and behavior during neurodevelopment.
Coley AA, Gao WJ., Free PMC Article | 10/24/2020 |
| PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus. | PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus.
Mardones MD, Jorquera PV, Herrera-Soto A, Ampuero E, Bustos FJ, van Zundert B, Varela-Nallar L. | 08/22/2020 |
| Uncoupling the linkage between Preso and PSD-95 attenuated the stability of this complex and suppressed the regulatory effect of Preso on the NO response. In addition, phosphorylation of NMDAR by cyclin-dependent kinase 5 (CDK5) was shown to be responsible for the Preso-mediated Ca(2+) response, which was dependent on the interaction between Preso and CDK5. | Preso regulates NMDA receptor-mediated excitotoxicity via modulating nitric oxide and calcium responses after traumatic brain injury.
Luo P, Li X, Wu X, Dai S, Yang Y, Xu H, Jing D, Rao W, Xu H, Gao X, Fei Z, Lu H., Free PMC Article | 07/18/2020 |
| The association between PSD-95 and KIF5A was dose-dependent on Staufen protein. | Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions.
Yoo KS, Lee K, Oh JY, Lee H, Park H, Park YS, Kim HK., Free PMC Article | 06/13/2020 |
| Disrupting nNOS-postsynaptic density-95 (PSD-95) coupling in the anterior cingulate cortex decreased the expression of Histone deacetylase 2 (HDAC2), and inhibited contextual fear generalization at a remote time point. | Uncoupling nNOS-PSD-95 in the ACC can inhibit contextual fear generalization.
Qin C, Bian XL, Cai CY, Chen C, Zhou Y, Lin YH, Tao Y, Wu HY, Chang L, Luo CX, Zhu DY. | 04/11/2020 |